DNA has revealed potential animal COVID carriers at the Wuhan market, but what does that tell us about the start of the pandemic? Roland talks to two of the experts behind the new analysis: Dr Florence Débarre and Professor Eddie Holmes. Also, we look into Europe’s grand new space ambitions. ESA director general Josef Aschbacher gives Roland the details of the space agency’s out-of-this-world plans. And Beethoven's last DNA: a hairy story of his family and genetic afflictions. Dr Tristan Begg shares how the composer’s tresses unlocked new information about his life and death. Image credit: Eddie Holmes Producer: Roland Pease 
Assistant producer: Sophie Ormiston

Animals at the Wuhan Market

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They were the best northern and southern lights in decades, but why? And what’s next? We hear from astrophysicist Steph Yardley about the solar maximum, geomagnetic storms and atmospheric spectaculars. Also, the impossible heatwave in the Philippines made possible by global warming – the analysis of a continent-spanning climate extreme by the World Weather Attribution collaboration. Getting close up to raging tornadoes in order to fill in the big gaps that remain in the science of their development. And the tale of the lizard’s tail, and how it could lead to safer buildings in the future.  (Photo: The aurora borealis, also known as the 'northern lights’, are seen over The Roaches near Leek, Staffordshire, Britain, May 10, 2024. Credit: Carl Recine/Reuters) Presenter: Roland Pease
Producer: Jonathan Blackwell

Aurora Bore-WOW-lis

Could future blood transfusions be made safer by mixing in a new bacterial enzyme? Every year 118 million blood donations need to be carefully sorted to ensure the correct blood types go to the right patients. Prof Martin Olsson, of Lund University in Sweden, and colleagues in Denmark have published a study that suggests an enzyme made by bacteria in our gut could edit our blood cells to effectively convert type A, B and AB to type O. This would be a step towards a universal blood type that could be given to any patient.  Papua New Guinea’s Naomi Longa is a “Sea Woman of Melanesia”. She works to train local women from the Kimbe Bay region of the Coral Triangle to dive, snorkel, navigate and use AI to monitor the coral reefs there. She is winner of this year’s Whitley Award, and tells us why it is socially and scientifically useful to get locals - specifically females - involved in conservation efforts there.   Data scientist and roboticist Prof Daniele Rus of MIT has been using Machine Learning to decipher structure in a vast swath of Sperm Whale song data from Dominica. They have discovered a set of patterns and rules of context that seem to govern the way sperm whales structure their distinctive sets of clicks. The next step? See if we can decode any semantic content…  Also, 200 years after Beethoven’s 9th symphony premiered, science says its composer couldn’t hold a beat. A cautionary tale of the hubris of genetic data miners, Laura Wesseldijk describes to Roland how she and her collaborators designed the paradoxical study to point out the limitations of finding any sort of “musical genius” genes with contemporary techniques.  Presenter: Roland Pease 
Producer: Alex Mansfield
Production Coordinator: Jana Bennett-Holesworth (Image: Two Sperm Whales, Caribbean Sea, Dominica. Credit: Reinhard Dirscherl via Getty Images)

Changing blood types and whale grammar

As bird flu is found in US farm cats fed on raw cow’s milk, chimpanzees are observed eating infected bat dung instead of vegetables. There is a constant threat of infections crossing from species to us and also from species to other species, particularly because of what we do. That is, after all, what happened to start the pandemic. We hear about the ongoing struggles of the Chinese virologist who broke his instructions in China in order to share the first COVID genetic data. And a strange tale of how tobacco growing might provide bat viruses a path into other species. Presenter: Roland Pease
Producer: Alex Mansfield
Production co-ordinator: Jana Bennett-Holesworth Image: Cows on an American cattle farm (Credit: Adam Davis/EPA-EFE/REX/Shutterstock)

Crossover infections

Friday, April 13th 2029 – mark it in your calendar. That’s the day an asteroid the size of an aircraft carrier will fly past Earth, closer than some satellites. Don’t worry – it will miss, but it’ll will pass so close to Earth that it will be visible to the naked eye of 2 billion people, particularly in North Africa and Western Europe. Roland Pease this week attended the Apophis T-5 Years conference at the European Space Research and Technology Centre (ESTEC) in the Netherlands, meeting astronomers scrambling to get missions up to the object to learn what kind of threats such asteroids might pose to us in the future and to discuss the science of planetary defence.  NASA’s OSIRIS-APEX, a follow-on to OSIRIS-REx, will study the physical changes due to the gravitational forces from the Earth as it closely passes us by. But will there be an armada of spacecraft sent to monitor Apophis? The European Space Agency hope to gather support for their own mission, RAMSES. Presenter: Roland Pease
Producer: Jonathan Blackwell Image Credit: JPL/Caltech

An armada for asteroid Apophis?

A black hole just discovered in our Milky Way galaxy, weighing 33 times the mass of the Sun, and dating back to near the time of the Big Bang, gives new clues to the origins of this dark astronomical mysteries. And dancing with a Sun-like star in our galactic neighbourhood, it offers a great opportunity for astronomers to take a detailed look in coming years, as astronomer Professor Gerry Gilmore of Cambridge University tells the programme.   Presenter Roland Pease has headed to the lab of Professor Ludovic Orlando in Toulouse, France where they are extracting ancient DNA from horses as part of a project called “Horsepower” - to reveal how our prehistoric ancestors tamed and domesticated these powerful animals (long after cattle and sheep) and in the process helped shape the extraordinary history of the first states of China and Mongolia.   
  
And a deep look into the mechanisms of addiction – showing how drugs of abuse, such as cocaine, hijack the neuronal pathways that had evolved to drive our innate needs such as eating and drinking. Roland hears from psychiatrist Eric J. Nestler of the Friedman Brain Institute at Icahn School of Medicine at Mount Sinai in New York, how this could one day improve addiction treatments.   Presenter: Roland Pease 
Producer: Jonathan Blackwell 
Production Coordinator: Jana Bennett-Holesworth  (Image: An artist's impression shows the orbits of the most massive stellar black hole in our galaxy, dubbed Gaia BH3, and a companion star. Credit: European Southern Observatory via Reuters)

Animals at the Wuhan Market

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