Suffering from incessant fevers, muscle pain, and mysterious nodules across his body for nine years, Chuck's hope was fading. No doctor could explain his sporadic flu-like symptoms. Then, he crossed paths with Dr. Daniel Kastner, an unconventional and brilliant physician with a unique approach to disease research. Together with his colleagues at the National Institutes of Health, their groundbreaking discovery might just hold the key to Chuck's medical mystery. See omnystudio.com/listener for privacy information.

Case #10: Chuck & Dr. Kastner

How terrifying would it be to fight an unknown enemy? One you don’t recognize and didn’t see coming? What if that enemy was coming from within; a disease that even doctors couldn’t identify? Nearly half of all Americans suffer from some chronic illness and many struggle for an accurate diagnosis.
Every other week on Symptomatic, host Lauren Bright Pacheco unravels the medical mystery of a patient’s baffling symptoms and explores how their lives were turned upside down in search of answers. 
From the first signs of trouble, through a swirl of misdirection and failed treatment attempts, to the final relief at a confirmed diagnosis - these are their stories. This is Symptomatic.
And for Season 2, we want to hear from you! Tell us what you think of the show or share your own medical mystery by emailing us at Symptomatic@iHeartMedia.com.

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Lauren is a professionally trained dancer whose biggest strength has always been finding expression and connection through movement. However, as she pursued her college career, she felt her body slowing down. Simple exercises became challenging, and her flexibility turned into stiffness. Lauren’s condition worsened after having children, and she periodically had to rely on crutches to accommodate her growing immobility. She was desperate for a doctor who could help her. Without a proper diagnosis, she was being torn between maintaining her two passions: dancing and family. See omnystudio.com/listener for privacy information.

Case #16: Lauren

For decades, Eliza dismissed her GI flare-ups and irritated skin. But after the birth of her first child, her concerns escalated, fearing she might faint while caring for her baby. She turned to her sister, who had paralleling symptoms, to explore any potential connection between their experiences. Ignoring the burning pains for so long, Eliza and her doctors dive into her symptomatic past and family history. They uncover a diagnosis that would restore normalcy in her life. See omnystudio.com/listener for privacy information.

Case #15: Eliza

Maria is a neurological specialist who became a patient herself when she noticed problems with her mobility. She started to experience cramps in her hands that soon prevented her from driving or tying her shoes. As she saw her ability to care for her patients gradually decline, she faced the skepticism of her colleagues and the fear of not finding a diagnosis. Maria raced to get answers before she lost not only her profession but her whole way of life, as well. See omnystudio.com/listener for privacy information.

Case #14: Maria

At just 7 years old, Alisha was diagnosed with plaque psoriasis - a condition that manifested in overwhelming flare-ups, covering nearly 90% of her body. Enduring both the physical toll and the harsh judgment of ignorant peers and their parents, she became so self-conscious about showing her skin. She would wear long sleeves in the middle of summer, would never go to the beach, and even feared she would never again be able to feel rain on her skin again. Alisha goes on a long, desperate journey to find a treatment for this disease, seeking not only physical relief but also respite from the mental and emotional trauma of living with psoriasis. See omnystudio.com/listener for privacy information.

Case #13: Alisha

In this bonus segment, host Lauren Bright Pacheco checks in with Michele from Case #09 to share feedback from the Symptomatic community. See omnystudio.com/listener for privacy information.

Case #10: Chuck & Dr. Kastner

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