Gene therapy holds the promise to permanently cure diseases that have been considered life-long challenges. But the complexity of rewriting DNA is truly huge and lives in its own special kind of big-data world. On this episode, you'll meet David Born, a computational biologist who uses Python to help automate genetics research and helps move that work to production.

#335: Gene Editing with Python

Talk Python to Me is a weekly podcast hosted by developer and entrepreneur Michael Kennedy. We dive deep into the popular packages and software developers, data scientists, and incredible hobbyists doing amazing things with Python. If you're new to Python, you'll quickly learn the ins and outs of the community by hearing from the leaders. And if you've been Pythoning for years, you'll learn about your favorite packages and the hot new ones coming out of open source.

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Do you know what custom GPTs are? They're configurable and shareable chat experiences with a name, logo, custom instructions, conversation starters, access to OpenAI tools, and custom API actions. And, you can build them with Python! Ian Maurer has been doing just that and is here to share his experience building them.

#456: Building GPT Actions with FastAPI and Pydantic

Interested in data science but you're not quite working in it yet? In software, getting that very first job can truly be the hardest one to land. On this episode, we have Avery Smith from Data Career Jumpstart here to share his advice for getting your first data job.

#455: Land Your First Data Job

Do you have data that you pull from external sources or is generated and appears at your digital doorstep? I bet that data needs processed, filtered, transformed, distributed, and much more. One of the biggest tools to create these data pipelines with Python is Dagster. And we are fortunate to have Pedram Navid on the show this episode. Pedram is the Head of Data Engineering and DevRel at Dagster Labs. And we're talking data pipelines this week at Talk Python.

#454: Data Pipelines with Dagster

Have you ever been wait around for pip to do its thing while installing packages or syncing a virtual environment or through some higher level tool such as pip-tools? Then you'll be very excited to hear about the tool just announced from Astral called uv. It's like pip, but 100x faster. Charlie Marsh from Ruff fame and founder of Astral is here to dive in. Let's go.

#453: uv - The Next Evolution in Python Packages?

Have you heard of Quart? It's the fully-async version of Flask created by Philip Jones who is working closely with the Flask team on these parallel projects. The TL;DR; version is that if you want to take advantage of async and await and you're using Flask, you want to give Quart a solid look. We've spoken to Philip previously about Quart. This time around here's here to share his top Quart extensions and libraries you can adopt today.

#335: Gene Editing with Python

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