Ep #66: Histamines and Perimenopause and Menopause with Dr. Tania Dempsey

Dr. Tania Dempsey is our special guest for this interview. Dr. Dempsey is an expert in chronic disease, autoimmune disorders, and mast cell activation syndrome. She talks about PCOS, histamine intolerance, mast cells, and mast cell activation syndrome. 1:09 Introduction to Dr. Tania Dempsey, MD 1:26 Histamines-What they are? How Histamines affect perimenopause and menopause 3:30 Mast cell activation and methylation metabolism of histamines and why that is important 5:15 Mast cells and the link to hormones and inflammation 9:18 Women are more prone to mast cell syndrome and Dr. Dempsey explains this 11:14 Things to keep in mind with hormone therapy and mast cell activation 12:20 Is this a new thing that could be happening or exacerbated during perimenopause and menopause? 15:20 The lightbulb moment for Dr. Dempsey and mast cells 17:10 The good news 18:19 How diet is important to mast cell activation and inflammation, support methylation, support liver detox pathways, support the immune system 19:20 Immune dysregulation in perimenopause and menopause and how this differs from auto-immune conditions 23:02 How would someone know if they have mast cell syndrome? 26:20 Relationship to heavy periods 27:40 What is suggested for women with histamine intolerance or mast cell syndrome? 30:00 Nutritional suggestions and a low histamine diet (link to her blog) and figuring out what works for you. Why you need to be aware of leftover foods and restricting foods so much that you end up with nutritional deficiencies. 32:40 Supplement suggestions DAO Enzyme, Vitamin C, and Quercitin. The importance of knowing your COMT enzymes when taking Quercetin. 36:26 Vitamin D is an essential hormone we don't make and key to immune function 39:35 The symptoms your might be experiencing and the overlap between signs and symptoms in perimenopause and menopause  43:56 Foods that are high in histamines or foods that cause an increase a release in histamines 46:50 Is there a recovery process where you are more tolerant or stabilization of mast cells?

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