C16 Biosciences wants to replace palm oil, a major contributor to deforestation and climate change, with a lab-grown substitute. Should the synthetic biology startup start small in the personal care market or dive into booming lab-grown food market?

How to Launch a New Biosciences Product: Start Small or Dive in?

Cold Call distills Harvard Business School's legendary case studies into podcast form. Hosted by Brian Kenny, the podcast airs every two weeks and features Harvard Business School faculty discussing cases they've written and the lessons they impart.

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In March 2020, Twiddy & Company, a family-owned vacation rental company known for hospitality rooted in personal interactions, needed to adjust to contactless, remote customer service. With the upcoming vacation season thrown into chaos by the COVID-19 pandemic, president Clark Twiddy had a responsibility to the company’s network of homeowners who rented their homes through the company, to guests who had booked vacations, and to employees who had been recruited by Twiddy’s reputation for treating staff well. Who, if anyone, could he afford to make whole and keep happy?

The Importance of Trust for Managing Through a Crisis

Ferran Adrià, chef at legendary Barcelona-based restaurant elBulli, was facing two related decisions. First, he and his team must continue to develop new and different dishes for elBulli to guarantee a continuous stream of innovation, the cornerstone of the restaurant's success. But they also need to focus on growing the restaurant’s business. Can the team balance both objectives?

Lessons in Business Innovation from Legendary Restaurant elBulli

In 2020, Amazon built a shelter for women and families experiencing houselessness on its campus in Seattle, Washington. The shelter was operated in partnership with a nonprofit organization known as Mary’s Place and was designed to address what had become an urgent problem for Seattle and many other wealthy American cities, where communities were being displaced by a lack of affordable housing. Amazon’s partnership with Mary’s Place was an experiment in addressing this problem at its core, using some of the firm’s own resources to fund living space for unhoused families. But critics argued that Amazon’s apparent charity was misplaced because the company and other tech giants were actually making the problem worse. Instead, they argued, government and nonprofits should solve these societal issues. Harvard Business School professors Debora Spar and Paul Healy explore the role business plays in causing and addressing the larger problem of unhoused communities in American cities in the case, “Hitting Home: Amazon and Mary’s Place.”

Amazon in Seattle: The Role of Business in Causing and Solving a Housing Crisis

Özyeğin Social Investments was founded by Hüsnü Özyeğin, one of Turkey's most successful entrepreneurs, with a focus on education, health, gender equality, rural development, and disaster relief in Turkey. Harvard Business School senior lecturer Christina Wing and Murat Özyeğin (MBA 2003) discuss how the company is a model for making a significant impact across multiple sectors of society through giving and how that legacy can be sustained in the future.

Sustaining a Legacy of Giving in Turkey

In the spring of 2021, Raymond Jefferson (MBA 2000) applied for a job in President Joseph Biden’s administration. Ten years earlier, false allegations had been used to force him to resign from his prior U.S. government position as assistant secretary of labor for veterans’ employment and training in the U.S. Department of Labor. Jefferson filed a federal lawsuit against the U.S. government to clear his name and used his entire life savings to pursue the case for eight years. Why, after such a traumatic and humiliating experience, would Jefferson want to work in government again?

How to Launch a New Biosciences Product: Start Small or Dive in?

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