Gabriel Victora joins Immune to review how high affinity antibodies are produced in the germinal centers of secondary lymphoid tissues. Hosts: Vincent Racaniello, Stephanie Langel, Cynthia Leifer, and Brianne Barker Guest:  Gabriel Victora Subscribe (free): Apple Podcasts, Google Podcasts. RSS, email Become a patron of Immune! Links for this episode  Concerto in B (TWiV 161) Visualizing antibody affinity maturation (Science) Restricted B cell clonality after boosting (Cell) Time stamps by Jolene. Thanks!  Music by Steve Neal. Immune logo image by Blausen Medical  Send your immunology questions and comments to immune@microbe.tv

Immune 52: B cell boot camp with Gabriel Victora

A podcast about the body's defenders against disease.

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Immune presents three stories: intranasal neomycin and antiviral immunity, sexual dimorphism in skin immunity, and maternal diet changes infant microbes that alter gut DC responses and respiratory health. Hosts: Stephanie Langel, Cynthia Leifer, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode  MicrobeTV Discord Server Intranasal neomycin as antiviral (PNAS) Sexual dimorphism in skin immunity (Science) Maternal diet and infant respiratory health (Immunity) Time stamps by Jolene. Thanks!  Music by Steve Neal. Immune logo image by Blausen Medical  Send your immunology questions and comments to immune@microbe.tv

Immune 80: Intranasal neomycin; sex hormones and skin immunity; and maternal diet and infant microbiomes

Immune explains how antibody-mediated depletion of myeloid-hematopoietic stem cells in aged mice restores characteristic features of a more youthful immune system, including increasing common lymphocyte progenitors, naive T cells and B cells, while decreasing age-related markers of immune decline. Hosts: Vincent Racaniello, Cynthia Leifer, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts. RSS, email Become a patron of Immune! Links for this episode  MicrobeTV Discord Server Depleting My-HSC rejuvenates aged immunity (Nature) Time stamps by Jolene. Thanks!  Music by Steve Neal. Immune logo image by Blausen Medical  Send your immunology questions and comments to immune@microbe.tv

Immune 79: Spa therapy for the immune system

Immune discusses responses in a COVID hypervaccinated individual, synthetically glycosylated antigens for the antigen-specific suppression of established immune responses,  gut bacteria–derived serotonin promotes immune tolerance in early life, and mucosal and systemic immune correlates of viral control after SARS-CoV-2 infection challenge. Hosts: Vincent Racaniello, Steph Langel, Cynthia Leifer, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts. RSS, email Become a patron of Immune! Links for this episode  MicrobeTV Discord Server Adaptive immune responses preserved in hypervaccinated individual (Lancet) Synthetically glycosylated antigens for antigen-specific suppression of established immune responses (Nat Biomed Eng) Gut bacteria–derived serotonin promotes immune tolerance in early life (Sci Immunol) Immune correlates of viral control after SARS-CoV-2 challenge in adults (Sci Immunol) Time stamps by Jolene. Thanks!  Music by Steve Neal. Immune logo image by Blausen Medical  Send your immunology questions and comments to immune@microbe.tv

Immune 78: Tolerance and tolerating many vaccines

Immune reviews research showing that the migration of neutrophils between endothelial cells activates bactericidal function via mechanosensing. Hosts: Vincent Racaniello, Steph Langel, Cynthia Leifer, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts. RSS, email Become a patron of Immune! Links for this episode  MicrobeTV Discord Server Trans endothelial migration activates neutrophil killing (Immunity) Time stamps by Jolene. Thanks!  Music by Steve Neal. Immune logo image by Blausen Medical  Send your immunology questions and comments to immune@microbe.tv

Immune 77: Squeezing the most killing out of neutrophils

Juliet Morrison joins Immune to discuss her career and the research of her laboratory showing that pleural macrophages translocate to the lung during infection to promote improved influenza outcomes. Hosts: Vincent Racaniello, Steph Langel, Cynthia Leifer, and Brianne Barker Guest: Juliet Morrison Click arrow to play Download Immune 76 (48 MB .mp3, 67 min) Subscribe (free): Apple Podcasts, Google Podcasts. RSS, email Become a patron of Immune! Links for this episode  MicrobeTV Discord Server Publishing is broken (Solving for Science) Pleural macrophages move to the lung during influenza (PNAS) Time stamps by Jolene. Thanks!  Music by Steve Neal Immune logo image by Blausen Medical  Send your immunology questions and comments to immune@microbe.tv

Immune 52: B cell boot camp with Gabriel Victora

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