Kirsty Young's castaway this week is the cardiologist Jane Somerville. Now an Emeritus Professor in her discipline at Imperial College London she's gained a worldwide reputation for her pioneering work on congenital heart disease. She began studying medicine in the early 1950s when only a very few women were admitted through the doors of medical school. Since then she's been responsible for ground-breaking advances in cardiovascular treatment and founded the World Congress of Paediatric Cardiology. She had something of a role model in her mother, a hard-working, clever, successful woman too. Her early years as a pupil at a boys' school in Wales must also have prepared her for making her way in such a heavily male-dominated profession. She has a reputation for being straight-talking, and her late husband used to urge her to be more "prudent", but, she says, "it wasn't fun to be prudent: it was much more fun to be mafioso and naughty." Producer: Cathy Drysdale.

Jane Somerville

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Kirsty Young's castaway is Chris Hadfield. He was the first Canadian commander of the International Space Station and took part in three space missions spending a total of 166 days orbiting the Earth. He has spent over 14 hours doing two space walks.  He flew his first eight day mission into space in 1995 during which he visited the Russian space station Mir. In 2001 he paid his first visit to the International Space Station to help install Canadarm2, a robot arm helping to build the station which was launched three years previously. In 2012 he began his final five month stay in space on board the ISS. It was on this mission that his videos of life in space - including a film of him singing David Bowie's Space Oddity and accompanying himself on guitar - led to him enjoying a huge following on social media.  Chris was born in 1959 in Ontario, the second of five children: his father was a pilot and the family lived on a farm. He mapped out his future career aged nine when he watched Neil Armstrong become the first person to walk on the moon in 1969. In pursuit of his dream Chris first become an Air Cadet, then attended military college, becoming a fighter pilot and then a test pilot, as well as an aeronautical engineer. He finally achieved his ambition of becoming an astronaut in 1992.  He went onto become the Chief of Robotics at the NASA Astronaut Office and Chief of International Space Station Operations at the Johnson Space Centre in Houston, Texas. Following his final space mission, Chris retired from the Canadian Space Agency in July 2013. Amongst the awards he's received are the military Meritorious Service Cross, NASA's Exceptional Service Medal and the Queen's Diamond Jubilee Medal. Producer: Cathy Drysdale.

Commander Chris Hadfield

Kirsty Young's castaway is Kylie Minogue. With seven number ones and ten million singles sold in the UK, she is the third-biggest selling female artist in Britain and has sold around 70 million records worldwide.  Born in Melbourne in 1968, Kylie and her sister Dannii began their careers as child actors on Australian television. At 17, Kylie landed the role of Charlene Mitchell in the soap opera Neighbours and her on-screen wedding to Jason Donovan's character Scott Robinson was watched by twenty million people in the UK alone.  Her recording career began after she was spotted singing at a charity event in 1987. Within months she had released a cover version of "Locomotion" which became the biggest-selling Australian single of the decade. Following the single's success, her first hit with record producers Stock, Aitken and Waterman was "I Should Be So Lucky": her debut album sold seven million copies. At the age of 21, a romance with INXS lead singer Michael Hutchence led to a change in her image. In 2000, inspired by 1970s disco and assisted by gold hot pants, her single "Spinning Around" became her first British number one for a decade. She also sang to an estimated global audience of 3.7 billion at the closing ceremony of the Sydney Olympics. In May 2005 she was diagnosed with breast cancer: following treatment she resumed the tour 18 months later.  Producer: Cathy Drysdale.

Kylie Minogue

Kirsty Young's castaway is the surgeon, author and former Reith lecturer, Atul Gawande. A general and endocrine surgeon in Boston, he is professor in both the Department of Health Policy & Management at the Harvard School of Public Health and the Department of Surgery at Harvard Medical School. Born in Brooklyn, he is the son of two doctors who came to the US to study medicine. After graduating from Stanford and studying Philosophy, Politics and Economics at Oxford, he embarked on a brief political career, working for Bill Clinton's presidential campaign and on his health and social policy in the White House following his election. When Clinton's health policy reform floundered, Atul returned to Harvard to finish the medical degree he'd started after Oxford. During his surgical residency he began writing for the online magazine Slate and he's been writing for the New Yorker since 1998. His 2009 article "The Cost Conundrum" was cited by President Barack Obama during his attempt to get the healthcare reform legislation through Congress. Atul has published four books to date about the achievements, but also the limitations, of medicine. In 2014 he presented the BBC's Reith Lectures, delivering a series of four talks titled The Future of Medicine. Producer: Cathy Drysdale.

Atul Gawande

Kirsty Young's castaway this week is Sandi Toksvig. Host of BBC Radio 4's News Quiz until June 2015, she is also a writer and comedian and recently entered the world of politics, helping to found the Women's Equality Party. Her parents were both broadcasters: her mother worked as a studio manager and announcer before she married, her Danish father's job as a foreign correspondent took the family around the world. Sandi and her siblings spent much of their childhood in the United States and when she was "asked to leave" yet another American school, her parents sent her to boarding school in England. She soon decided to lose her strong American accent and went on to Cambridge, where she performed in the Footlights. In addition to writing, her most recent acting role was in Call the Midwife and she continues to appear regularly on TV and radio shows as a panelist: she is to start as the next host of QI, taking over from Stephen Fry. She's also Chancellor of Portsmouth University.

Sandi Toksvig

Kirsty Young's castaway is filmmaker Gurinder Chadha. Writer, director and producer behind the films Bend it like Beckham, Bhaji on the Beach and Bride and Prejudice, she began her career as a BBC news reporter. She was born in Kenya to Sikh parents and grew up in Southall in West London. Her political awakening came in her teens in the 1970s against the backdrop of the National Front and race riots in the capital. The bands she listened to, including the Clash, the Jam and the Specials, were fixtures at the Rock Against Racism concerts which galvanised her desire to make a difference. Bend it Like Beckham, which launched the career of Keira Knightly, is now a hit musical on the West End stage. Her next film, Viceroy's House, tackles the Partition of India in 1947. She was awarded an OBE in the 2006 Queen's Birthday Honours List for her services to the British Film Industry. Producer: Paula McGinley.

Jane Somerville

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