In honor of her 70th birthday, Rob is looking back at his 2021 conversation with the amazing Oprah Winfrey! The two friends discuss what it means to live in gratitude, the wisdom of Toni Morrison, meeting your heroes, and so much more.

Re-Release: Oprah Winfrey (2021)

This is literally a podcast where people I love, admire, and know well will be in a safe space to really let their hair down (assuming they have any). I will cover the thoughtful to the extremely random. So join me and my guests from the world of movies, TV, sports, music, and culture for fun, wide-ranging, free-wheeling conversations.

Society & Culture

Personal Journals

History

Philosophy

Places & Travel

Jeff and Rob both love performing drama AND comedy! Jeff Daniels joins Rob Lowe to discuss how working with Jim Carrey on “Dumb and Dumber” taught him fearlessness, committing to his thick accent in Netflix’s “A Man in Full,” his memories of the brilliant James Gandolfini, their experiences performing Aaron Sorkin dialogue, watching Shirley MacLaine and Debra Winger's process on "Terms of Endearment,” and why Jeff settled down in Michigan.

Got a question for Rob? Call our voicemail at (323) 570-4551. Your question could get featured on the show!

Jeff Daniels: Pitching a No-Hitter

Rob is entering his 60s and committing to a better diet…with the help of the esteemed Dr. Mark Hyman! Dr. Mark Hyman (renowned physician, medical advisor to the Clintons, and the host of “The Doctor's Farmacy” podcast) joins Rob Lowe to discuss the Ozempic revolution, the real key to longevity, the obesity statistic that shocked Rob, what foods to avoid, and the easy-to-find snacks that just might help you live longer. 

Got a question for Rob? Call our voicemail at (323) 570-4551. Your question could get featured on the show!

Dr. Mark Hyman: It's What You Eat!

Comedian, actor, and podcaster Paul Scheer joins Rob Lowe to discuss celebrity-owned restaurants, the “M*A*S*H” theme song, why the team behind “The League” decided to end the show while they were still on top, Rob’s traumatic childhood talent show memory, the greatest audition story ever, and Paul’s new memoir, “Joyful Recollections of Trauma.” Pre-order “Joyful Recollections of Trauma” now - out May 21st! 

Got a question for Rob? Call our voicemail at (323) 570-4551. Your question could get featured on the show!

Paul Scheer: Phyllis Diller’s Chili

Kelly Ripa joins Rob Lowe to discuss getting “knighted” by Disney, the joys of working with her husband, why Rob was one of Kelly’s favorite guest co-hosts, trying out the Oculus headset, Rob’s 60th birthday party, her podcast “Let's Talk Off Camera with Kelly Ripa,” and her big goal to get out of hair and makeup!

Got a question for Rob? Call our voicemail at (323) 570-4551. Your question could get featured on the show!

Kelly Ripa: Jiminy Cricket

Katey and Rob looooove talking to other sober people! Actress and musician Katey Sagal joins Rob Lowe to discuss her new podcast with husband Kurt Sutter, the joys of sobriety, the passing of her godfather Norman Lear, being a Keith Richards girl, working with the amazing John Ritter, why “Sons of Anarchy” convinced Rob to go buy a biker jacket, being of service, and much more. 

Listen to Katey’s new podcast, “PIE with Kurt Sutter and Katey Sagal!” Got a question for Rob? Call our voicemail at (323) 570-4551. Your question could get featured on the show!

Re-Release: Oprah Winfrey (2021)

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