Sep 01 2023 This Week in Cardiology

ESC Wrap-up 1: Obesity, heart failure with preserved EF and reduced EF, AF, frailty, evidence translation, and catheter ablation are the topics John Mandrola, MD, discusses in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. FRAIL AF    -FRAIL-AF Study    https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.123.066485    -The Most Important Study From ESC: FRAIL-AF    https://www.medscape.com/viewarticle/996063 II. STEP-HFpEF Wegovy Scores HFpEF Benefits in People With Obesity https://www.medscape.com/viewarticle/995844 GLP-1 Agonist Semaglutide in HFpEF Cleared Low Bar https://www.medscape.com/viewarticle/995872 Semaglutide’s Big Step in HFpEF With Obesity: Investigator Inteview https://www.medscape.com/viewarticle/995673    -Semaglutide in Obese Patients With  HFpEF    https://www.nejm.org/doi/full/10.1056/NEJMoa2306963 III. NOAH AFNET 6 Anticoagulation No Benefit in Presumed AF Detected by Cardiac Devices https://www.medscape.com/viewarticle/995861 How Much AF Warrants Anticoagulation? NOAH-AFNET 6 Provides Clues https://www.medscape.com/viewarticle/995871    -NOAH AFNET-6 – NEJM    https://www.nejm.org/doi/full/10.1056/NEJMoa2303062 IV. ADVENT Pulsed Field Ablation Challenges Conventional Devices in AF https://www.medscape.com/viewarticle/995884 Pulsed Field Ablation Noninferior but Underwhelming in ADVENT https://www.medscape.com/viewarticle/995898    -PPFA vs Thermal Ablation for PAF    https://www.nejm.org/doi/10.1056/NEJMoa2307291 V. BUDAPEST CRT Impact of RV Pacing in Heart Failure, CRT Benefit Shown in BUDAPEST-CRT https://www.medscape.com/viewarticle/996035 Supporting Evidence for a Common Practice: BUDAPEST CRT https://www.medscape.com/viewarticle/995880    -BUDAPEST CRT Study: European Heart Journal    https://doi.org/10.1093/eurheartj/ehad591 VI. CASTLE HTx Advanced HF No Obstacle to AF Ablation Success: CASTLE-HTx https://www.medscape.com/viewarticle/995897 AF Ablation in End-Stage HF: Is CASTLE-HTx Too Good to Be True? https://www.medscape.com/viewarticle/995974    -CASTLE AF (2018)    https://www.nejm.org/doi/full/10.1056/nejmoa1707855    -CASTLE HTx    https://www.nejm.org/doi/full/10.1056/NEJMoa2306037 You may also like: Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine https://www.medscape.com/features/public/machine The Bob Harrington Show with Stanford University Chair of Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact [email protected]