This 2019 episode notes that the Catacombs contain the bones of an estimated 6 to 7 million people, and explains that their history is really two interconnected stories of mines and human remains. See omnystudio.com/listener for privacy information.

SYMHC Classics: Paris Catacombs

Join Holly and Tracy as they bring you the greatest and strangest Stuff You Missed In History Class in this podcast by iHeartRadio.

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Once Dr. Ray Damadian had the idea to create a machine that used nuclear magnetic resonance to capture diagnostic data by scanning a human body, he still had to build it. And though he did, other scientists got credit for inventing the MRI.  
Research:

Bashir U, Rock P, Murphy A, et al. T2 relaxation. Reference article, Radiopaedia.org. https://doi.org/10.53347/rID-16494
Bellis, Mary. "A Guide to Magnetic Resonance Imaging (MRI)." ThoughtCo, Apr. 5, 2023, thoughtco.com/magnetic-resonance-imaging-mri-1992133
Bloch, Felix. “The Principle of Nuclear Induction.” Nobel Lecture. Dec. 11, 1952. https://www.nobelprize.org/uploads/2018/06/bloch-lecture-1.pdf
Bloembergen, Nicolas. “Edward M. Purcell (1912-97).” Nature. April 17, 1997. https://www.nature.com/articles/386662a0.pdf
Britannica, The Editors of Encyclopaedia. "Isidor Isaac Rabi". Encyclopedia Britannica, 3 Apr. 2024, https://www.britannica.com/biography/Isidor-Isaac-Rabi
Britannica, The Editors of Encyclopaedia. "Paul Lauterbur". Encyclopedia Britannica, 2 May. 2024, https://www.britannica.com/biography/Paul-Lauterbur
Britannica, The Editors of Encyclopaedia. "nuclear magnetic resonance". Encyclopedia Britannica, 25 Apr. 2024, https://www.britannica.com/science/nuclear-magnetic-resonance
Damadian, Raymond, and Jeff Kinley. “Gifted Mind: The Dr. Raymond Damadian Story.” Master Books. 2015.
Damadian R. “Tumor detection by nuclear magnetic resonance.” Science. 1971 Mar 19;171(3976):1151-3. doi: 10.1126/science.171.3976.1151
Deutsch, Claudia H. “Patent Fights Aplenty for MRI Pioneer.” New York Times. July 12, 1997. https://www.nytimes.com/1997/07/12/business/patent-fights-aplenty-for-mri-pioneer.html
“Dr. Edward Purcell, 84, Dies; Shared Nobel Prize in Physics.” New York Times. March 10, 1997. https://www.nytimes.com/1997/03/10/us/dr-edward-purcell-84-dies-shared-nobel-prize-in-physics.html
Drew Z, Jones J, Murphy A, et al. Longitudinal and transverse magnetization. Reference article, Radiopaedia.org (Accessed on 03 Jun 2024) https://doi.org/10.53347/rID-60738
"Edward Mills Purcell." National Academy of Sciences. 2000. Biographical Memoirs: Volume 78. Washington, DC: The National Academies Press. doi: 10.17226/9977
:"Felix Bloch." National Academy of Sciences. 1994. Biographical Memoirs: Volume 64. Washington, DC: The National Academies Press. doi: 10.17226/4547
LAUTERBUR, P. Image Formation by Induced Local Interactions: Examples Employing Nuclear Magnetic Resonance. Nature242, 190–191 (1973). https://doi.org/10.1038/242190a0
National Academies of Sciences, Engineering, and Medicine. 1994. Biographical Memoirs: Volume 64. Washington, DC: The National Academies Press. https://doi.org/10.17226/4547.
National Academies of Sciences, Engineering, and Medicine. 2000. Biographical Memoirs: Volume 78. Washington, DC: The National Academies Press. https://doi.org/10.17226/9977.
Hofstadter, Robert. “Felix Bloch.” National Academies of Sciences, Engineering, and Medicine. 1994. Biographical Memoirs: Volume 64. Washington, DC: The National Academies Press. https://doi.org/10.17226/4547.
Isidor Isaac Rabi – Biographical. NobelPrize.org. Nobel Prize Outreach AB 2024. Tue. 4 Jun 2024. https://www.nobelprize.org/prizes/physics/1944/rabi/biographical/
Jones J, Howden W, Rock P, et al. T1 relaxation time. Reference article, Radiopaedia.org (Accessed on 03 Jun 2024) https://doi.org/10.53347/rID-6315
Luiten, A.L. (1999). Magnetic Resonance Imaging: A Historical Introduction. In: Magnetic Resonance Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-03800-0_1
MacWilliams, B. Russian claims first in magnetic imaging. Nature426, 375 (2003). https://doi.org/10.1038/426375a
“Magnetic Resonance Imaging (MRI).” National Institute of Biomedical Imaging and BioEngineering. https://www.nibib.nih.gov/science-education/science-topics/magnetic-resonance-imaging-mri
“The Man Who Did Not Win.” Sydney Morning Herald. October 17, 2003. https://www.smh.com.au/national/the-man-who-did-not-win-20031017-gdhlpn.html
Odeblad E, Lindström G. Some preliminary observations on the proton magnetic resonance in biologic samples. Acta Radiol Suppl (Stockholm). 2008 Aug;434:57-61. doi: 10.1080/02841850802133337
Paul C. Lauterbur – Biographical. NobelPrize.org. Nobel Prize Outreach AB 2024. Tue. 4 Jun 2024. https://www.nobelprize.org/prizes/medicine/2003/lauterbur/biographical/
Plewes, Donald B., PhD, and Walter Kucharczyk, PhD. “Physics of MRI: A Primer.” MR Physics for Clinicians. April 12, 2012. https://doi.org/10.1002/jmri.23642
Prasad, Amit. “The (Amorphous) Anatomy of an Invention: The Case of Magnetic Resonance Imaging (MRI).” Social Studies of Science, vol. 37, no. 4, 2007, pp. 533–60. JSTOR, http://www.jstor.org/stable/25474534
Purcell, E.M. et al. “Resonance Absorption by Nuclear Magnetic Moments in a Solid.” Physics Review. January 1, 1946. https://journals.aps.org/pr/pdf/10.1103/PhysRev.69.37
“Raymond Damadian.” Lemelson-MIT. https://lemelson.mit.edu/award-winners/raymond-damadian
Sandomir, Richard. “Raymond Damadian, Creator of the First M.R.I. Scanner, Dies at 86.” New York Times. Aug. 17, 2022. https://www.nytimes.com/2022/08/17/science/raymond-damadian-dead.html
Serai, Suraj, PhD, and Tony Dandino. “Why are MRI scans so loud?” Cincinnati Children’s Radiology Department Blog. October 13, 2016. https://radiologyblog.cincinnatichildrens.org/whats-with-all-the-noise/
Sullivan, Walter. “Five Named as Winners of Lasker Medical Research Awards.” New York Times. Nov. 15, 1984. https://www.nytimes.com/1984/11/15/us/five-named-as-winners-of-lasker-medical-research-awards.html
National Academies of Sciences, Engineering, and Medicine. 2000. Biographical Memoirs: Volume 78. Washington, DC: The National Academies Press. https://doi.org/10.17226/9977.
Wakefield, Julie. “The ‘Indomitable’ MRI.” Smithsonian. June 2000. https://www.smithsonianmag.com/science-nature/the-indomitable-mri-29126670/
See omnystudio.com/listener for privacy information.

Magnetic Resonance Imaging, Part 2

Who invented the MRI? Well, that's actually tricky to say, and it is a topic that still opens debate. In this first part, we'll talk about the various developments in physics that led to the idea of an MRI machine even existing.
Research:

Bashir U, Rock P, Murphy A, et al. T2 relaxation. Reference article, Radiopaedia.org. https://doi.org/10.53347/rID-16494
Bellis, Mary. "A Guide to Magnetic Resonance Imaging (MRI)." ThoughtCo, Apr. 5, 2023, thoughtco.com/magnetic-resonance-imaging-mri-1992133
Bloch, Felix. “The Principle of Nuclear Induction.” Nobel Lecture. Dec. 11, 1952. https://www.nobelprize.org/uploads/2018/06/bloch-lecture-1.pdf
Bloembergen, Nicolas. “Edward M. Purcell (1912-97).” Nature. April 17, 1997. https://www.nature.com/articles/386662a0.pdf
Britannica, The Editors of Encyclopaedia. "Isidor Isaac Rabi". Encyclopedia Britannica, 3 Apr. 2024, https://www.britannica.com/biography/Isidor-Isaac-Rabi
Britannica, The Editors of Encyclopaedia. "Paul Lauterbur". Encyclopedia Britannica, 2 May. 2024, https://www.britannica.com/biography/Paul-Lauterbur
Britannica, The Editors of Encyclopaedia. "nuclear magnetic resonance". Encyclopedia Britannica, 25 Apr. 2024, https://www.britannica.com/science/nuclear-magnetic-resonance
Damadian, Raymond, and Jeff Kinley. “Gifted Mind: The Dr. Raymond Damadian Story.” Master Books. 2015.
Damadian R. “Tumor detection by nuclear magnetic resonance.” Science. 1971 Mar 19;171(3976):1151-3. doi: 10.1126/science.171.3976.1151
Deutsch, Claudia H. “Patent Fights Aplenty for MRI Pioneer.” New York Times. July 12, 1997. https://www.nytimes.com/1997/07/12/business/patent-fights-aplenty-for-mri-pioneer.html
“Dr. Edward Purcell, 84, Dies; Shared Nobel Prize in Physics.” New York Times. March 10, 1997. https://www.nytimes.com/1997/03/10/us/dr-edward-purcell-84-dies-shared-nobel-prize-in-physics.html
Drew Z, Jones J, Murphy A, et al. Longitudinal and transverse magnetization. Reference article, Radiopaedia.org (Accessed on 03 Jun 2024) https://doi.org/10.53347/rID-60738
"Edward Mills Purcell." National Academy of Sciences. 2000. Biographical Memoirs: Volume 78. Washington, DC: The National Academies Press. doi: 10.17226/9977
:"Felix Bloch." National Academy of Sciences. 1994. Biographical Memoirs: Volume 64. Washington, DC: The National Academies Press. doi: 10.17226/4547
LAUTERBUR, P. Image Formation by Induced Local Interactions: Examples Employing Nuclear Magnetic Resonance. Nature242, 190–191 (1973). https://doi.org/10.1038/242190a0
National Academies of Sciences, Engineering, and Medicine. 1994. Biographical Memoirs: Volume 64. Washington, DC: The National Academies Press. https://doi.org/10.17226/4547.
National Academies of Sciences, Engineering, and Medicine. 2000. Biographical Memoirs: Volume 78. Washington, DC: The National Academies Press. https://doi.org/10.17226/9977.
Hofstadter, Robert. “Felix Bloch.” National Academies of Sciences, Engineering, and Medicine. 1994. Biographical Memoirs: Volume 64. Washington, DC: The National Academies Press. https://doi.org/10.17226/4547.
Isidor Isaac Rabi – Biographical. NobelPrize.org. Nobel Prize Outreach AB 2024. Tue. 4 Jun 2024. https://www.nobelprize.org/prizes/physics/1944/rabi/biographical/
Jones J, Howden W, Rock P, et al. T1 relaxation time. Reference article, Radiopaedia.org (Accessed on 03 Jun 2024) https://doi.org/10.53347/rID-6315
Luiten, A.L. (1999). Magnetic Resonance Imaging: A Historical Introduction. In: Magnetic Resonance Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-03800-0_1
MacWilliams, B. Russian claims first in magnetic imaging. Nature426, 375 (2003). https://doi.org/10.1038/426375a
“Magnetic Resonance Imaging (MRI).” National Institute of Biomedical Imaging and BioEngineering. https://www.nibib.nih.gov/science-education/science-topics/magnetic-resonance-imaging-mri
“The Man Who Did Not Win.” Sydney Morning Herald. October 17, 2003. https://www.smh.com.au/national/the-man-who-did-not-win-20031017-gdhlpn.html
Odeblad E, Lindström G. Some preliminary observations on the proton magnetic resonance in biologic samples. Acta Radiol Suppl (Stockholm). 2008 Aug;434:57-61. doi: 10.1080/02841850802133337
Paul C. Lauterbur – Biographical. NobelPrize.org. Nobel Prize Outreach AB 2024. Tue. 4 Jun 2024. https://www.nobelprize.org/prizes/medicine/2003/lauterbur/biographical/
Plewes, Donald B., PhD, and Walter Kucharczyk, PhD. “Physics of MRI: A Primer.” MR Physics for Clinicians. April 12, 2012. https://doi.org/10.1002/jmri.23642
Prasad, Amit. “The (Amorphous) Anatomy of an Invention: The Case of Magnetic Resonance Imaging (MRI).” Social Studies of Science, vol. 37, no. 4, 2007, pp. 533–60. JSTOR, http://www.jstor.org/stable/25474534
Purcell, E.M. et al. “Resonance Absorption by Nuclear Magnetic Moments in a Solid.” Physics Review. January 1, 1946. https://journals.aps.org/pr/pdf/10.1103/PhysRev.69.37
“Raymond Damadian.” Lemelson-MIT. https://lemelson.mit.edu/award-winners/raymond-damadian
Sandomir, Richard. “Raymond Damadian, Creator of the First M.R.I. Scanner, Dies at 86.” New York Times. Aug. 17, 2022. https://www.nytimes.com/2022/08/17/science/raymond-damadian-dead.html
Serai, Suraj, PhD, and Tony Dandino. “Why are MRI scans so loud?” Cincinnati Children’s Radiology Department Blog. October 13, 2016. https://radiologyblog.cincinnatichildrens.org/whats-with-all-the-noise/
Sullivan, Walter. “Five Named as Winners of Lasker Medical Research Awards.” New York Times. Nov. 15, 1984. https://www.nytimes.com/1984/11/15/us/five-named-as-winners-of-lasker-medical-research-awards.html
National Academies of Sciences, Engineering, and Medicine. 2000. Biographical Memoirs: Volume 78. Washington, DC: The National Academies Press. https://doi.org/10.17226/9977.
Wakefield, Julie. “The ‘Indomitable’ MRI.” Smithsonian. June 2000. https://www.smithsonianmag.com/science-nature/the-indomitable-mri-29126670/
See omnystudio.com/listener for privacy information.

Magnetic Resonance Imaging, Part 1

This 2019 episode examines thyroid disease through history, and the physics lecture heard by Saul Hertz in the 1930s that changed the treatment of hyperthyroidism forever.  See omnystudio.com/listener for privacy information.

SYMHC Classics: Radioiodine Therapy

Holly and Tracy discuss ways that they like to make popcorn, and historical recipes that used popcorn. They also talk about the incorrect assumption that iodized salt is the cause of an overall rise in blood pressure statistics. See omnystudio.com/listener for privacy information.

Behind the Scenes Minis: Salty Popcorn

People started adding iodine to salt because in some parts of the world serious, chronic iodine deficiency was incredibly widespread, which was causing a range of health issues. But how was that solution arrived at?
Research:

"Iodine." World of Chemistry, Gale, 2000. Gale In Context: Science, link.gale.com/apps/doc/CV2432500388/GPS?u=mlin_n_melpub&sid;=bookmark-GPS&xid;=42a73bea. Accessed 17 May 2024.
"Iodine." World of Scientific Discovery, Gale, part of Cengage Group, 2007. Gale In Context: Science, link.gale.com/apps/doc/CV1648500324/GPS?u=mlin_n_melpub&sid;=bookmark-GPS&xid;=fabf4422. Accessed 17 May 2024.
Bishai, David and Ritu Nalubola. “The History of Food Fortification in the United States: Its Relevance for Current Fortification Efforts in Developing Countries.” Economic Development and Cultural Change , Vol. 51, No. 1 (October 2002). https://www.jstor.org/stable/10.1086/345361
Cameron, A.T. “Iodine Prophylaxis and Endemic Goitre.” Canadian Public Health Journal, Vol. 21, No. 11 (NOVEMBER, 1930). Via JSTOR. https://www.jstor.org/stable/41976052
Cameron, A.T. “Iodine Prophylaxis and Endemic Goitre.” Canadian Public Health Journal, Vol. 21, No. 10 (OCTOBER, 1930). Via JSTOR. https://www.jstor.org/stable/41976030
Cavanaugh, Ray. “How the arrival of iodized salt 100 years ago changed America.” Washington Post. 5/1/2024. https://www.washingtonpost.com/history/2024/05/01/iodized-salt-100-years-deficiency/
Feyrer, James et al. “The Cognitive Effects of Micronutrient Deficiency.” Journal of the European Economic Association, April 2017. Via JSTOR. https://www.jstor.org/stable/10.2307/90023421
Goodman, Johnah. “A National Evil: Jonah Goodman on the curse of the goitre in Switzerland.” London Review of Books. 11/30/2003. https://www.lrb.co.uk/the-paper/v45/n23/jonah-goodman/a-national-evil
Kimball, O.P. “History of the Prevention of Endemic Goitre.” Bulletin of the World Health Organization. 1953.
Kohn, Lawrence. “Goiter, Iodine and George W. Goler: The Rochester Experiment.” Bulletin of the History of Medicine, Vol. 49, No. 3 (FALL, 1975). Via JSTOR. https://www.jstor.org/stable/44450239
Leung, Angela M et al. “History of U.S. iodine fortification and supplementation.” Nutrients vol. 4,11 1740-6. 13 Nov. 2012, doi:10.3390/nu4111740
Markel, H. “’When it rains it pours’: endemic goiter, iodized salt, and David Murray Cowie, MD.” American journal of public health vol. 77,2 (1987): 219-29. doi:10.2105/ajph.77.2.219
Markel, Howard. “A grain of salt.” The Milbank quarterly vol. 92,3 (2014): 407-12. doi:10.1111/1468-0009.12064
McIntire, Tracey. “Gunpowder and Seaweed: The Story of Iodine.” National Museum of Civil War Medicine. 10/19/2022. https://www.civilwarmed.org/story-of-iodine/
Newton, David E. "Iodine." Chemical Elements, edited by Kathleen J. Edgar, 2nd ed., UXL, 2010. Gale In Context: Science, link.gale.com/apps/doc/CV2640200041/GPS?u=mlin_n_melpub&sid;=bookmark-GPS&xid;=a54dec8e. Accessed 17 May 2024.
Niazi, Asfandyar Khan et al. “Thyroidology over the ages.” Indian journal of endocrinology and metabolism vol. 15,Suppl 2 (2011): S121-6. doi:10.4103/2230-8210.83347
Olsen, Robert. “Endemic Goiter in Switzerland: A Review of Recent Contributions to Its Etiology, Incidence, and Prevention.” Public Health Reports (1896-1970) , Jun. 9, 1933. Via JSTOR. https://www.jstor.org/stable/4580807
Pearce, Elizabeth N. “Is Iodine Deficiency Reemerging in the United States?” AACE Clinical Case Reports. Volume 1, Issue 1, Winter 2015. https://www.sciencedirect.com/science/article/pii/S2376060520303680
Stanbury, John, and John T. Dunn. "Iodine." Encyclopedia of Food and Culture, edited by Solomon H. Katz, vol. 2, Charles Scribner's Sons, 2003, pp. 281-283. Gale In Context: U.S. History, link.gale.com/apps/doc/CX3403400349/GPS?u=mlin_n_melpub&sid;=bookmark-GPS&xid;=12f688cc. Accessed 17 May 2024.
Zimmermann, Michael B. and Maria Andersson, GLOBAL ENDOCRINOLOGY: Global perspectives in endocrinology: coverage of iodized salt programs and iodine status in 2020, European Journal of Endocrinology, Volume 185, Issue 1, Jul 2021, Pages R13–R21, https://doi.org/10.1530/EJE-21-0171
Zoltan, Melanie Barton. "Salt." Food: In Context, edited by Brenda Wilmoth Lerner and K. Lee Lerner, vol. 2, Gale, 2011, pp. 699-702. In Context Series. Gale In Context: Global Issues, link.gale.com/apps/doc/CX1918600212/GPS?u=mlin_n_melpub&sid;=bookmark-GPS&xid;=21e3cd86. Accessed 17 May 2024.
See omnystudio.com/listener for privacy information.

SYMHC Classics: Paris Catacombs

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