The Stem Cell Podcast

The Stem Cell Podcast episodes:

• 06.11.2024

  Ep. 269: “iPSC Technology” Featuring Dr. Sebastian Diecke

  Guest: Dr. Sebastian Diecke is a Group Leader and Stem Cell Core Director at the Max Delbrück Center, where his research focuses on iPSCs and organoid models. He talks about the early days of iPSC research, developing organoids from endangered rhinoceros,...

  
• 05.28.2024

  Ep. 268: “Tissue Formation” Featuring Dr. Shukry Habib

  Guest: Dr. Shukry Habib is an Associate Professor in the Department of Biomedical Sciences at the Université de Lausanne. His lab works at the intersection of stem cell biology, biophysics, and tissue engineering to investigate how tissues form. He talks about...

  
• 05.14.2024

  Ep. 267: “Embryo Morphogenesis” Featuring Dr. Shankar Srinivas

  Guest: Dr. Shankar Srinivas is a Professor of Developmental Biology in the Department of Physiology Anatomy and Genetics based in the Institute for Developmental and Regenerative Medicine at the University of Oxford. He is also a Zeitlyn Fellow and Tutor in...

  
• 04.30.2024

  Ep. 266: “From Stem Cells to Cortical Circuits” Featuring Dr. Pierre Vanderhaeghen

  Guest: Dr. Pierre Vanderhaeghen is a Professor and Principal Investigator at VIB-KU Leuven Center for Brain & Disease Research. His lab studies the mechanisms of cortical development and brain evolution. He talks about species-specific neuronal development, human neuron excitability, and playing in a...

  
• 04.16.2024

  Ep. 265: “RNA Glycosylation” Featuring Dr. Ryan Flynn

  Guest: Dr. Ryan Flynn is a Principal Investigator at Boston Children’s Hospital and an Assistant Professor in the Stem Cell and Regenerative Biology Department at Harvard University. His lab explores the interface between RNA and glycans. He talks about the discovery...

  
• 04.02.2024

  Ep. 264: “Planarian Regeneration” Featuring Dr. Blair Benham-Pyle

  Guest: Dr. Blair Benham-Pyle is an Assistant Professor at Baylor College of Medicine. She talks about how multipotent cells in Schmidtea mediterranea enable whole-body regeneration. She also discusses the effects of the mechanical environment on stem cell fate. Featured Products and Resources: Register for ISSCR 2024! Get...

  
• 03.19.2024

  Ep. 263: “ISSCR 2024: The Global Stem Cell Event” Featuring Drs. Amander Clark, Agnete Kirkeby, and Malin Parmar

  Guests: Dr. Amander Clark is the President of the International Society for Stem Cell Research (ISSCR) and Founding Director of the Center for Reproductive Science, Health, and Education at the University of California, Los Angeles. Dr. Agnete Kirkeby is a Program...

  
• 03.05.2024

  Ep. 262: “Glia in the Gut” Featuring Dr. Marissa Scavuzzo

  Guest: Dr. Marissa Scavuzzo is an HHMI Hanna H. Gray Fellow at Case Western Reserve University School of Medicine. Her research focuses on enteric glia regulation in the healthy and diseased gut. She talks about how glial cell subtypes affect intestinal...

  
• 02.20.2024

  Ep. 261: “Building Neuromuscular Tissues” Featuring Dr. Ritu Raman

  Guest: Dr. Ritu Raman is the d’Arbeloff Career Development Assistant Professor of Mechanical Engineering at MIT, where her lab uses robotics and tissue engineering to treat muscle loss. She talks about light-activated muscle grafts, magnetic microparticles to control forces exerted on cells, and...

  
• 02.06.2024

  Ep. 260: “Synchronized Tissue Regeneration” Featuring Dr. Shiri Gur-Cohen

  Guest: Dr. Shiri Gur-Cohen is an Assistant Professor of Medicine in the Division of Regenerative Medicine at UC San Diego. Her lab studies epithelial stem cells throughout their lifetimes. She talks about lymphatics in the intestinal stem cell niche, 3D imaging techniques,...

  
• 01.23.2024

  Ep. 259: “Regenerative Neurobiology” Featuring Dr. Malin Parmar

  Dr. Malin Parmar is a Professor at Lund University and a New York Stem Cell Foundation – Robertson Investigator. Her research aims to understand cell fate specification in the developing brain and in human neural progenitor cells using cell-based models...

  
• 01.09.2024

  Ep. 258: “The Musculo-Skeletal Axis” Featuring Dr. Olivier Pourquié

  Dr. Olivier Pourquié is the Frank Burr Mallory Professor of Pathology and Professor in the Department of Genetics at Harvard Medical School. His work focuses on the segmentation clock and the development of muscles and vertebrae. He talks about studying...

  
• 12.12.2023

  Ep. 257: “Retinal Regeneration” Featuring Drs. Hwee Goon Tay and Beau Fenner

  Dr. Hwee Goon Tay is an Assistant Professor at the Duke-National University of Singapore Medical School and Dr. Beau Fenner is an Ophthalmologist at the Singapore National Eye Centre. Their work focuses on cell therapy for degenerative retinal diseases. They...

  
• 11.28.2023

  Ep. 256: “Epigenetics and Reprogramming” Featuring Dr. Jose Polo

  Dr. Jose Polo is a Professor of Epigenetics and the Director of the Centre for Epigenetics at the University of Adelaide. He is also a Professor in the Department of Anatomy and Developmental Biology at Monash University. His lab studies the...

  
• 11.14.2023

  Ep. 255: “Pathway to the Clinic” Featuring Drs. Stefan Irion and Viviane Tabar

  Dr. Stefan Irion is the Chief Scientific Officer of BlueRock Therapeutics and Dr. Viviane Tabar is the Chair of the Department of Neurosurgery at Memorial Sloan Kettering Cancer Center.  In this special episode, recorded in front of a live audience...

  
• 10.31.2023

  Ep. 254: “Muscle Regeneration” Featuring Dr. Helen Blau

  Dr. Helen Blau is the Donald E. and Delia B. Baxter Foundation Professor and Director of the Baxter Laboratory for Stem Cell Biology at Stanford University. Dr. Blau’s research focuses on the basic molecular mechanisms of stem cells and muscle...

  
• 10.17.2023

  Ep. 253: “Heart Failure Genes” Featuring Dr. Roger Foo

  Dr. Roger Foo is the Zayed bin Sultan Al Nahyan Professor of Medicine and Head of the Cardiovascular Research Institute at the National University of Singapore. His lab investigates the molecular mechanisms that regulate cardiac biology and disease. He talks...

  
• 10.03.2023

  Ep. 252: “Organ-on-a-Chip” Featuring Dr. Bas Trietsch

  Dr. Bas Trietsch is the Chief Technology Officer and Co-Founder at Mimetas, a company working to contribute to groundbreaking therapies with their screenable, physiologically relevant 3D human disease models. He talks about tissue-relevant models for drug discovery, and how organ-on-a-chip...

  
• 09.19.2023

  Ep. 251: “Post-Implantation Blastoids” Featuring Drs. Thorold Theunissen and Rowan Karvas

  Dr. Thorold Theunissen is an Assistant Professor of Developmental Biology at Washington University in St. Louis investigating the molecular basis of pluripotency, the mechanisms of trophoblast development, and the generation of stem cell-based embryo models.

  
• 09.05.2023

  Ep. 250: “Blastoid Development and Implantation” Featuring Dr. Nicolas Rivron

  Dr. Nicolas Rivron is a Principal Investigator at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences in Vienna. His group recreates embryonic development using mammalian stem cells in a dish to better understand the encoded principles of...

  
• 08.22.2023

  Ep. 249: “Live at NYSCF: Overcoming Obstacles in Stem Cell Research” Featuring Drs. Laura Andres-Martin, Daniel Paull, and Raeka Aiyar

  Dr. Laura Andres-Martin is a Research Investigator, Oncology, Dr. Daniel Paul is the Senior VP, Discovery & Platform Development, and Dr. Raeka Aiyar is the VP, Scientific & DEIB Outreach at the New York Stem Cell Foundation (NYSCF). This episode...

  
• 08.08.2023

  Ep. 248: “Biomaterials and Tissue Engineering” Featuring Dr. Nathaniel Huebsch

  Dr. Nathaniel Huebsch is an Assistant Professor of Biomedical Engineering at Washington University in St. Louis. His lab focuses on understanding how mechanical cues originating at cell-cell and cell-extracellular matrix contacts influence signaling and fate. They are especially interested in...

  
• 07.25.2023

  Ep. 247: “Neurological Disorders” Featuring Dr. Thomas Durcan

  Dr. Thomas Durcan is an Associate Professor and Director of the Early Drug Discovery Unit at the Montreal Neurological Institute. He oversees a team of 40+ research staff and students, committed to applying patient-derived stem cells towards the development of...

  
• 07.11.2023

  ISSCR 2023: On the Ground

  In June 2023, we attended ISSCR 2023, the annual meeting of the International Society for Stem Cell Research, in Boston. We spoke with delegates about their research and impressions of the meeting, including their reasons for attending, what they were...

  
• 06.27.2023

  Ep. 245: “Cellular Diversity” Featuring Dr. Thomas Zwaka

  Dr. Thomas Zwaka is the Director of the Huffington Center for Cell-Based Research in Parkinson's Disease and a Professor of Regenerative and Developmental Biology at the Icahn School of Medicine at Mount Sinai. His research focuses on fundamental questions surrounding...

  
• 06.18.2023

  ISSCR 2023: Day 4

  In June 2023, Daylon and Arun attended the International for Stem Cell Research's (ISSCR) annual meeting in Boston, Massachusetts, and recorded daily episodes discussing highlights of the final day of the meeting.

  
• 06.17.2023

  ISSCR 2023: Day 3

  In June 2023, Daylon and Arun attended the International Society for Stem Cell Research's (ISSCR) annual meeting in Boston, Massachusetts, and recorded daily episodes discussing highlights of the third day of the meeting.

  
• 06.16.2023

  ISSCR 2023: Day 2

  In June 2023, Daylon and Arun attended the International Society for Stem Cell Research’s (ISSCR) annual meeting in Boston, Massachusetts, and recorded daily episodes discussing highlights of the second day of the meeting.

  
• 06.15.2023

  ISSCR 2023: Day 1

  In June 2023, Daylon and Arun attended the International Society for Stem Cell Research's (ISSCR) annual meeting in Boston, Massachusetts, and recorded daily episodes discussing highlights of the first day of the meeting. They discuss the pre-meeting workshops, including Arun's...

  
• 06.13.2023

  Ep. 244: “The Mammalian Lung” Featuring Dr. Emma Rawlins

  Dr. Emma Rawlins is a Senior Group Leader at the Gurdon Institute in the Department of Physiology, Development, and Neuroscience at the University of Cambridge. She talks about modeling fetal lung development using organoids, using single-cell RNA sequencing to create...

  
• 05.30.2023

  Ep. 243: “Ethics and Policy” Featuring Dr. Insoo Hyun

  Dr. Insoo Hyun is the Director of the Center for Life Sciences and Public Learning at the Museum of Science in Boston, and a Member of the Harvard Medical School Center for Bioethics. He talks about embryo models for early...

  
• 05.16.2023

  Ep. 242: “Spinal Cord Injury” Featuring Dr. Aileen Anderson

  Dr. Aileen Anderson is the Director of the Sue and Bill Gross Stem Cell Research Center at the University of California, Irvine. Her lab investigates the role of inflammatory mechanisms in degeneration and regeneration in the injured central nervous system....

  
• 05.02.2023

  Ep. 241: “The Biology of HSCs” Featuring Dr. Shannon McKinney-Freeman

  Dr. Shannon McKinney-Freeman is a Principal Investigator and Member at St. Jude Children's Research Hospital. Her lab focuses on the fundamental biology of hematopoietic stem cells (HSCs).  She talks about the role of HSCs in sickle cell disease and the...

  
• 04.18.2023

  Ep. 240: “The Human Brain” Featuring Dr. Sergiu Pașca

  Dr. Sergiu Pașca is the Kenneth T. Norris, Jr. Professor of Psychiatry and Behavioral Sciences at Stanford University and the Bonnie Uytengsu and Family Director of the Stanford Brain Organogenesis Program. His lab has pioneered and applied neural organoid and...

  
• 04.04.2023

  Ep. 239: “Academic Publishing” Featuring Dr. Stylianos Lefkopoulos

  Dr. Stylianos Lefkopoulos is an Associate Editor of Nature Cell Biology. He talks about a day in the life of an editor and what he looks for in a manuscript. He also discusses the role of preprints in publishing and promoting...

  
• 03.21.2023

  Ep. 238: “Skeletal Stem Cells” Featuring Dr. Noriaki Ono

  Dr. Noriaki Ono is an Associate Professor at the University of Texas Health Center at Houston. His research focuses on bone development and regeneration. He talks about in vivo lineage tracing techniques and how early perichondrial cells contribute to developing...

  
• 03.07.2023

  Ep. 237: “Epithelial and Organoid Systems” Featuring Dr. Ryan Conder

  Dr. Ryan Conder is the Director of Epithelial and Organoid Systems at STEMCELL Technologies.  He talks about the next phase in organoid research and what questions organoids can help answer. He also discusses his experience doing a postdoc in Vienna,...

  
• 02.21.2023

  Ep. 236: “ISSCR 2023: The Future Starts Here” Featuring Keith Alm, Dr. Haifan Lin, and Dr. David Scadden

  Keith Alm is the CEO, Dr. Haifan Lin is the President, and Dr. David Scadden is 2023 Annual Meeting Program Chair of the ISSCR. They talk about the upcoming annual meeting being held this year in Boston, a biotech hub...

  
• 02.07.2023

  Ep. 235: “New Therapies for Degenerative Disease” Featuring Dr. Lorenz Studer

  Dr. Lorenz Studer is the Director of the Center for Stem Cell Biology at Memorial Sloan Kettering Cancer Institute. His lab exploits recent advances in stem cell biology to develop new therapies for degenerative diseases and cancer. Their projects involve...

  
• 01.24.2023

  Ep. 234: “Engineered Tissue Assembly” Featuring Dr. Boyang Zhang

  Dr. Boyang Zhang is an Assistant Professor of Chemical Engineering at McMaster University. His lab uses advanced biofabrication techniques to build human micro-tissue models for predictive drug discovery and to construct functional macro-tissues for tissue regeneration in patients. He talks...

  
• 01.10.2023

  Ep. 233: “The Role of Podcasting in Science” Featuring Drs. Jason Goldsmith and Brenda Raud

  In this special episode, Daylon and Arun chat with Drs. Jason Goldsmith and Brenda Raud, the hosts of The Immunology Podcast. Recorded in-person and led by Dr. Nicole Quinn from STEMCELL Technologies, the four hosts discuss the impact that podcasting...

  
• 12.13.2022

  Ep. 232: “Neurodegenerative Diseases” Featuring Dr. Clive Svendsen

  Dr. Clive Svendsen is the Executive Director of the Regenerative Medicine Institute at Cedars-Sinai. His lab uses stem cells to develop models and treatments for neurodegenerative diseases. He talks about using stem cells to model spinal muscular atrophy and the...

  
• 11.29.2022

  Ep. 231: “Manipulating Stem Cell Fate” Featuring Dr. Shuibing Chen

  Dr. Shuibing Chen is the Kilts Family Professor of Surgery at Weill Cornell Medicine. Her lab uses hiPSCs and ESCs for disease modeling and drug screening, with a focus on diabetes and infectious diseases such as Zika and SARS-CoV-2. She...

  
• 11.15.2022

  Ep. 230: “Neuronal Diversity” Featuring Dr. Paola Arlotta

  Dr. Paola Arlotta is the Golub Family Professor of Stem Cell and Regenerative Biology at Harvard University. She is interested in understanding the molecular laws that govern the birth, differentiation, and assembly of the human brain’s cerebral cortex. She...

  
• 11.01.2022

  Ep. 229: “Cellular Reprogramming and Pluripotency” Featuring Dr. Jacob Hanna

  Dr. Jacob Hanna is an Associate Professor at the Weizmann Institute of Science and investigates cellular reprogramming and embryogenesis. This episode features a discussion on the challenges of growing embryo models in a roller culture system and the feasibility of...

  
• 10.18.2022

  Ep. 228: “Developing Regenerative Medicines” Featuring Dr. Stefan Irion

  Dr. Stefan Irion is the Senior Vice President of Research at BlueRock Therapeutics, a leading engineered cell therapy company with a mission to develop regenerative medicines for intractable diseases. He talks about the company's Parkinson's disease trial and the challenges...

  
• 10.04.2022

  Ep. 227: “Interspecies Chimeras” Featuring Dr. Jun Wu

  Dr. Jun Wu is an Assistant Professor at the University of Texas Southwestern. The Wu lab uses interspecies chimeras to study fundamental biology: conserved and divergent developmental programs, determination of body and organ size, species barriers, and cancer resistance. They...

  
• 09.20.2022

  Ep. 226: “The ‘Egg to Embryo’ Transition” Featuring Dr. Edward Grow

  Dr. Edward Grow is an Assistant Professor at the University of Texas, Southwestern. His lab studies reproductive biology, specifically the development of the egg and subsequently the fertilized embryo. He talks about regulating totipotency in ESCs, retroviral reactivation, and ex...

  
• 09.06.2022

  Ep. 225: “Self-Organization and Collective Behavior” Featuring Dr. Prisca Liberali

  Dr. Prisca Liberali is Senior Group Leader at the Friedrich Miescher Institute for Biomedical Research and an Assistant Professor at the University of Basel. Her research aims to understand the collective properties of organoid systems and their patterns, including how...

  
• 08.23.2022

  Ep. 224: “Standards for Stem Cell Research” Featuring Drs. Tenneille Ludwig, Peter Andrews, and Madeline Lancaster

  Drs. Tenneille Ludwig, Peter Andrews, and Madeline Lancaster are members of the ISSCR Standards Initiative for Pluripotent Stem Cell Research. They discuss the need for basic and preclinical standards to ensure rigor and reproducibility in stem cell research. They also...