Episode Highlights With Thomas Seyfried

• What cancer actually is and why it isn’t just genetic
• How mitochondria function is a big factor in the cancer equation
• What the Warburg study is and what it shows us about how cancer happens
• Why cyanide kills healthy cells but not tumor cells
• Cancer cells don’t use oxygen for energy, and what they use instead
• Warburg: cancer cells replace oxygen energy with fermentation energy
• How cancer cells use oxygen, not for energy but to create reactive oxygen species
• The only two fuels cancer cells use: glucose and the amino acid glutamine (both fermentable)
• His opinion: target the glucose and the glutamine simultaneously while transitioning the body to ketones
• The biggest cancer breakthrough in the last few decades? Reduction in smoking
• What are the root causes of cancer as a metabolic disease
• Provocative agents that increase the risk of cancer: chronic inflammation, age, carcinogenic chemicals, viruses, age, genes (like BRCA1)
• How to keep your mitochondria healthy to reduce the risk of cancer “Our genes are supremely capable of preventing cancer”
• Why he recommends periodic water fasting for mitochondria health
• How exercise helps support mitochondria
• What ketones are and why they are a super fuel for the body
• How to address the glutamine side of cancer cells
• What glutamine-targeting drugs are
• Why his approach is getting rid of cancer without the toxicity
• The reason that traditional cancer treatment like chemo and radiation can be more effective when used with metabolic therapies
• What he would do if he had cancer

“We can reduce the death rate by 50% if you view the tumor as a metabolic problem rather than a genetic problem” – Thomas Seyfried

Resources We Mention

• Cancer as a metabolic disease: On the origin, management and prevention of cancer by Thomas Seyfried
• Keto for Cancer: Ketogenic Metabolic Therapy as a Targeted Nutritional Strategy by Miriam Kalamian EdM MS CNS
• The Origin (and future) of the Ketogenic Diet - by Dr. Dominic D'Agostino and Travis Christofferson: Charity Publication: In support of Dr. Thomas Seyfrieds cancer research by Johnny Rockermeier, with Dr. Dominic D'Agostino
• Ravenous: Otto Warburg, the Nazis, and the Search for the Cancer-Diet Connection by Sam Apple