The Human Cell Atlas is a project that has 3000 researchers in over 94 countries working to collect samples of every single cell in the human body. The idea is that an interactive map of the body will be created. It will be a reference for what every kind of normal human cell should look like. But that will also vary depending on who you are and where you live. It will give doctors a tool to measure illness and disease and make diagnosis and treatment much quicker. The database will enable any doctor, anywhere in the world, with the right kind of interface, to access the information. It could be ground-breaking for the treatment of disease and the democratisation of healthcare.  Contributors: 
Dr Aviv Regev, one of the co-chairs of the Human Cell Atlas
Dr Sarah Teichmann from the Wellcome Sanger Institute and the University of Cambridge
Dr Piero Carninci, Geneticist, Transcriptome Technology and RIKEN Centre
Sean Bendall, Associate Professor of pathology and immunology at Stanford University Presented by Tanya Beckett
Produced by Louise Clarke
Researched by Anoushka Mutanda-Dougherty 
Edited by Tara McDermott
Technical Producer is Richard Hannaford
Production Co-ordinator is Jordan King Image: Medical Technology Stock Photo by Kentoh via Getty Images

What is the Human Cell Atlas?

The Inquiry gets beyond the headlines to explore the trends, forces and ideas shaping the world.

News

Last year the US state of Texas introduced a controversial law designed to control the huge number of undocumented migrants crossing its southern border with Mexico.   The law known as Senate Bill 4 or SB4, allows local and state police the power to arrest and charge people with a newly created state crime - ‘illegal entry’.     Immigration law has historically been handled by the federal government.  Crossing the border is a federal crime and addressed by immigration courts that fall under the justice department. Now Texas is embroiled in a legal battle and SB4 has been paused.  But it’s just the latest measure that Texas has taken to stop hundreds of thousands of migrants entering the US on its border.    Back in 2021 the state’s Governor, Greg Abbott launched a multi-billion   dollar border security programme known as Operation Lone Star.   Along with his Republican lawmakers, the Governor’s argument is that Texas has a legal right to defend itself and they allege that Democrat President Joe Biden has failed to secure the US southern border in violation of the law.
But with a Presidential election this November, it remains to be seen if Texas will have a more sympathetic ally in the White House in the future.  So, on this week’s Inquiry, we’re asking ‘Can Texas go it alone on border control?’  Contributors:  Dr. Ernesto Castañeda, Director of the Centre for Latin American and Latino Studies and it’s Immigration Lab, American University, Washington DC, USA  Dr James Henson, Director, Texas Politics Project, Department of Government, The University of Texas at Austin, USA. Denise Gilman, Clinical Professor, Co-Director Immigration Clinic, The University of Texas at Austin, School of Law, USA  Julia Gelatt, Associate Director, US Immigration Policy Programme, Migration Policy Institute, Washington DC, USA  Presenter: Charmaine Cozier 
Producer:  Jill Collins 
Researcher: Matt Toulson 
Editor: Tara McDermott 
Technical Producer:  Craig Boardman  
Production Co-ordinator:  Liam Morrey Image credit: Adam Davis via BBC Images

Can Texas go it alone on border control?

Beyonce has released an album that has gone straight to the top of the country music charts.   The 27 tracks include the work of many collaborators from the world of country music, including Black country artist Linda Martell and Dolly Parton’s 1974 song Jolene. It has been so well received it has become the fastest selling album of the year.   Beyonce is usually known for her pop and RnB. Her success in the country music genre has opened up a wider debate about where country music originates from, who it belongs to and its political associations.   This week on the Inquiry we are asking, who is country ? Contributors:  William Nash, Professor of American Studies and English at Middleburgh College
Francesca Inglese, assistant professor in the Department of Music at Northeastern University
Taylor Crumpton, music critic and culture writer from Dallas, Texas
Charles Hughes, associate professor at Rhodes College in Memphis, Tennessee and co-founder of the No Fences Review Presenter: Tanya Beckett
Producers: Louise Clarke and Lorna Reader
Editor: Tara McDermott
Technical Producer: Cameron Ward
Production Co-ordinator: Liam Morrey Image credit: Reuters

Who is country?

An increasing number of people are dying from misuse of synthetic opioids. In 2022, the US recorded over 70,000 overdose deaths involving synthetic opioids.  The government is spending billions to combat the effects of these super strength drugs.
Synthetic opioids, such as Fentanyl, are made in laboratories by using materials derived from the opium poppy. China is a major hub for the production of synthetic opioids, where it then makes its way to North America through Mexican drug cartels.  The lab-made drugs can be more deadly than the natural materials, but they are more easily accessible, and prevalence is rising across the world. In West Africa and the Middle East, tramadol is one of the most consumed synthetic drugs. The rise of synthetic opioids in the European market, which are being used as a substitute for a heroin shortage, is fuelling concern that these substances could lead to a rise in drug-related deaths.  This week on The Inquiry, we’re asking are synthetic opioids a global problem? Contributors 
Ric Treble, Forensic chemist and advisor to the Government’s Advisory Council on the Misuse of Drugs
Dr Angela Me, Chief of the Research and Trend Analysis Branch from the United Nations Office on Drugs and Crime
Ben Westhoff, author of Fentanyl, Inc and investigative journalist
Dr Vanda Felbab-Brown is a senior fellow in the Strobe Talbott Center for Security, Strategy, and Technology in the Foreign Policy program at Brookings Institution Production team
Presenter: Charmaine Cozier
Producers: Vicky Carter and Matt Toulson 
Researcher: Ajai Singh
Editor: Tara McDermott 
Technical Producer: Cameron Ward
Production Co-ordinator: Liam Morrey Image credit: mikroman6 via Getty Images

Are synthetic opioids a global problem?

Six months into Israel’s war in Gaza and with no sign of a ceasefire or breakthrough in securing the release of the 130 hostages, as  yet unaccounted for, pressure is mounting on Israel’s Prime Minister Benjamin Netanyahu.  There have been widespread protests in Tel Aviv and across Israel.  There have been calls both from home and abroad for an early election to be called.   And Israel’s greatest ally, the United States has sharpened its rhetoric in the past few weeks over Israel’s conduct of the war, with President Biden now saying that he believes Benjamin Netanyahu is making ‘a mistake’ in his handling of it.  For his part, the Israeli Prime Minister looks set to continue with his military offensive and has shown no indication so far that he is willing to step down or call an early election.   So, on this week’s Inquiry, we’re asking ‘How secure is Benjamin Netanyahu’s leadership?’ Contributors: 
Professor David Tal, the Yossi Harel Chair in Modern Israel Studies, University of Sussex, UK 
Natan Sachs, Director of the Centre for Middle East Policy,  The Brookings Institution, Washington DC, USA 
Aaron David Miller, Senior Fellow, Carnegie Endowment for International Peace,  Washington DC, USA 
Professor Tamar Hermann,  Senior Research Fellow, The Israel Democracy Institute, Jerusalem Presenter:  Tanya Beckett 
Producer:  Jill Collins 
Editor:  Tara McDermott 
Technical Producer:  Cameron Ward 
Production Co-ordinator:  Liam Morrey Image credit: Reuters via BBC Images

How secure is Benjamin Netanyahu’s leadership?

Multiple Sclerosis (MS) is a neurological disease which can lead to loss of mobility and vision. Almost 3 million people worldwide are affected by it. There is no cure, but attempts are being made to accelerate the healing process with treatments to restore what the disease has damaged. At the same time, scientists have recently discovered a link between MS and a common virus that the majority of us carry in our bodies. It had been known for years that there was a link between Multiple Sclerosis and Epstein-Barr virus (EBV). But then, a study finally proved the link. Now, trials are underway on potential vaccines against EBV and scientists are hopeful that this could be a gateway to preventing MS.  This week on the Inquiry we are asking: Are we close to a breakthrough for Multiple Sclerosis? Contributors: Tim Coetzee, Chief Advocacy, Services & Science Officer for the National MS Society, US
Tjalf Ziemssen, Professor of Clinical Neuroscience and Head of the Multiple Sclerosis Center and Neuroimmunological Laboratory, University Clinic Carl-Gustav Carus, Germany
Jeffrey Huang, Associate Professor of Biology, Georgetown University, US
Claire Shannon-Lowe, Associate Professor in Virology, Institute of Immunology and Immunotherapy at the University of Birmingham, UK Production team:  Presenter: Tanya Beckett
Producer: Matt Toulson
Researcher: Ajai Singh
Editor: Tara McDermott
Studio Manager: Hal Haines
Production Co-ordinator: Liam Morrey Image Credit: Shidlovski\Getty

What is the Human Cell Atlas?

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