We've heard a lot about the immune system during the COVID-19 pandemic, but of course our immune system fights off much more than the coronavirus. And while the immune system protects us brilliantly from countless pathogens every day, sometimes it can also attack our own bodies, causing harmful and even deadly inflammation. In this episode, host Steven Strogatz speaks with Shruti Naik, an immunologist and assistant professor of biological sciences at NYU's Langone Medical Center, to learn why the immune system works so well - and how that effectiveness can backfire.

Why Is Inflammation a Dangerous Necessity?

“The Joy of Why” is a Quanta Magazine podcast about curiosity and the pursuit of knowledge. The mathematician and author Steven Strogatz and the cosmologist and author Janna Levin take turns interviewing leading researchers about the great scientific and mathematical questions of our time. New episodes are released every other Wednesday.

Quanta Magazine is a Pulitzer Prize–winning, editorially independent online publication launched and supported by the Simons Foundation to illuminate big ideas in science and math through public service journalism.  Quanta’s reporters and editors focus on developments in mathematics, theoretical physics, theoretical computer science and the basic life sciences, emphasizing timely, accurate, in-depth and well-crafted articles for its broad discerning audience. In 2023, Steven Strogatz received a National Academies Eric and Wendy Schmidt Award for Excellence in Science Communications partly for his work on “The Joy of Why.”

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If superconductors — materials that conduct electricity without any resistance — worked at temperatures and pressures close to what we would consider normal, they would be world-changing. They could dramatically amplify power grids, levitate high-speed trains and enable more affordable medical technologies. For more than a century, physicists have tinkered with different compounds and environmental conditions in pursuit of this elusive property, but while success has sometimes been claimed, the reports were always debunked or withdrawn. What makes this challenge so tricky?

In this episode, Siddharth Shanker Saxena, a condensed-matter physicist at the University of Cambridge, gives co-host Janna Levin the details about why high-temperature superconductors remain so stubbornly out of reach.

Will Better Superconductors Transform the World?

Milk is more than just a food for babies. Breast milk has evolved to deliver thousands of diverse molecules including growth factors, hormones and antibodies, as well as microbes.

Elizabeth Johnson, a molecular nutritionist at Cornell University, studies the effects of infants’ diet on the gut microbiome. These studies could hold clues to hard questions in public health for children and adults alike. In this episode of “The Joy of Why” podcast, co-host Steven Strogatz interviews Johnson about the microbial components that make breast milk one of the most wondrous biofluids found in nature.

You can read the transcript for this episode and see the image of the micrograph Johnson references on our website.

What Does Milk Do for Babies?

Nothing escapes a black hole… or does it? In the 1970s, Stephen Hawking described a subtle process by which black holes can “evaporate,” with some particles evading gravitational oblivion. This phenomenon, now dubbed “Hawking radiation,” seems inherently at odds with general relativity, but it gets weirder still: If particles can escape, do they preserve some information about the matter that was obliterated? Leonard Susskind, a physicist at Stanford University, found himself at odds with Hawking when it came to answering this question. In this episode, co-host Janna Levin speaks with Susskind about the “black hole war” that ensued and the powerful scientific lessons that have radiated from one of the most famous paradoxes in physics.

Can Information Escape a Black Hole?

Birds flock. Locusts swarm. Fish school. In these chaotic assemblies, order somehow emerges. Collective behaviors differ in their details from one species to another, but they largely adhere to principles of collective motion that physicists have worked out over centuries. Now, using technologies that only recently became available, researchers have been able to study these patterns of collective animal behavior more closely than ever before. These new insights are unlocking some of the secret fitness advantages of living as part of a group rather than as an individual. The improved understanding of swarming pests such as locusts could also help to protect global food security.

In this episode, co-host Steven Strogatz interviews the evolutionary ecologist Iain Couzin about  how and why animals exhibit collective behaviors, and the secret advantages that arise from them.

How Is Flocking Like Computing?

Quantum teleportation isn’t just science fiction; it’s entirely real and happening in laboratories today. But teleporting quantum particles and information is a far cry from beaming people through space. In some ways, it’s even more astonishing. John Preskill, a theoretical physicist at the California Institute of Technology, is one of the leading theoreticians of quantum computing and information. In this episode, co-host Janna Levin interviews him about entanglement, teleporting bits from coast to coast, and the revolutionary promise of quantum technology.

Why Is Inflammation a Dangerous Necessity?

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