Agent Nick Fury is asked to fight the menace of Hydra after exiling himself in the Yukon since the end of the Cold War. The children of the former Hydra head, Baron Von Stucker, have taken charge of the terrorist organisation, and under the lead of his vicious daughter, Viper, Hydra has seized a deadly virus and threatens the destruction of America. The covert agency SHIELD brings Fury out of retirement to fight the terrorist.