The Curbsiders Internal Medicine Podcast

#113 Gout: Uric acid targets, urate lowering therapy, and random questions from social media


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Master the management of gout with tips from expert, Tuhina Neogi MD, PhD, Professor of Medicine at Boston University School of Medicine. Topics include: how to initiate and titrate urate lowering therapy, guidelines controversy over uric acid targets, colchicine & NSAIDS for anti-inflammatory prophylaxis, uricosuric agents, febuxostat, HLA B5801, use of uric acid levels in the acute setting and more random gout facts.

Full show notes available at http://thecurbsiders.com/podcast. Join our mailing list and receive a PDF copy of our show notes every Monday. Rate us on iTunes, recommend a guest or topic and give feedback at [email protected].

Credits:

  • Written and produced by: Matthew Watto MD
  • Hosts: Paul Williams MD, Stuart Brigham MD, Matthew Watto MD
  • Guest: Tuhina Neogi MD, PhD

Time Stamps

  • 00:00 Intro and guest bio
  • 01:30 Allopurinol initiation and titration
  • 07:10 Uricosuric therapy
  • 09:10 Controversy over uric acid targets for gout
  • 17:40 Parachutes and randomized controlled trials
  • 19:15 Colchicine or NSAIDS for prophylaxis
  • 23:20 Who needs febuxostat?
  • 26:20 When to refer for gout, HLA B5801, and checking uric acid levels in the acute setting  
  • 33:29 Take home points
  • 36:15 Outro

Tags: allopurinol, uric, urate, acid, level, therapy, management, gout, flare, crystal, arthritis, titration, probenecid, febuxostat, target, acr, acp, guidelines, nsaids, colchicine, hla b5801, septic, rheumatology, assistant, care, doctor, education, family, FOAM, FOAMim, FOAMed, health, hospitalist, hospital, internal, internist, meded, medical, medicine, nurse, practitioner, professional, primary, physician, resident, student

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