What Is Adrafinil?

Adrafinil (brand name Olmifon) is a stimulant commonly used to increase alertness and promote wakefulness. It is considered a nootropic medication; this means that it is intended to improve cognitive function, boost memory, and ultimately bring about increased productivity. It was developed in 1974 by two scientists who were working for a French pharmaceutical company called Laboratoire L. Lafon. It was formerly used in France to elevate mood, improve attention, promote wakefulness, and increase alertness, mostly in seniors [1].

Adrafinil works by increasing the levels of serotonin, histamine, and some other neurotransmitters in the brain. It does this by blocking their respective transporters, which in turn prevents their reuptake. High levels of these chemicals are known to impact wakefulness, mood, and alertness.

At this point, it is worth noting that although adrafinil is said to provide several cognitive-enhancing benefits, there is limited evidence that supports some of its effects. The drug may not be safe for repeated or long-term use. It is not approved by the US Food and Drug Administration (FDA). Also, France’s FDA withdrew its marketing permission in 2011. If you decide to take it, be sure to first seek advice from your doctor or healthcare provider.

The Normal Nootropic Dose

Adrafinil dosage requirements may vary from individual to individual. Although it is mostly available in dose strengths of 150 mg and 300 mg, people consider anywhere between 600 mg to 1200 mg as typical. However, many have reported achieving the expected results with doses as low as 150 mg.