the bioinformatics chat

#20 B cell receptor substitution profile prediction and SPURF with Kristian Davidsen and Amrit Dhar

04.30.2018 - By Roman CheplyakaPlay

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In this episode

Kristian Davidsen

and

Amrit Dhar

present their project called SPURF.

SPURF can predict the B cell receptor (BCR) substitution profile of a given clonal

family based on a single representative sequence from that family.

SPURF works by fitting a tensor regression model to publicly available

Rep-seq data.

Links:

Preprint: Predicting B Cell Receptor Substitution Profiles Using Public Repertoire Data

Blog post about SPURF by Erick Matsen

SPURF on GitHub

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