OptiCast - The Optimization Lab Podcast

Building Systems for Physiology Optimization w/Mike White - SLU-PP-332, DNP, & Peptides


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šŸŽ“ ABOUT THIS VIDEOĀ 
In this deeply insightful episode of OptiCast, Nathan speaks with Mike White — a researcher, coach, and educator — about the complexities of mitochondrial health, gut functionality, and how a systems-based approach transforms coaching and health outcomes. Whether you're a coach or an enthusiast, the conversation challenges conventional protocols and emphasizes upstream diagnostics.

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🧠 TIMESTAMPS 
00:00:00 - Introduction and episode overview
00:02:06 - Impact and risks of nicotine for gut health & cognition
00:07:21 - Mike White’s journey from debt to coaching success
00:14:25 - Transition from academia to real-world coaching
00:19:30 - Managing health markers and unexpected effects of supplements
00:27:09 - Upstream causes of IBS and gut health diagnostics
00:33:38 - Gut-brain connection and stress influence
00:39:35 - Managing testosterone and estrogen levels via gut health
00:44:49 - The importance of foundational knowledge over protocol obsession
00:55:22 - Building mitochondrial health through phased approaches
01:02:13 - Adjusting protocols based on metabolic and cellular signals
01:06:50 - Cycling mitochondrial agents and combining therapies
01:11:36 - Handling long-term fatigue & systemic health
01:23:02 - Working with shift workers and circadian disruptions
01:27:17 - Ironman-like training volume vs. fatigue management
01:32:24 - Use of propranolol for anxiety and peak week management
01:35:04 - Gut health’s role in androgen receptor sensitivity
01:37:00 - Coaching philosophy: humility, collaboration, continual learning
01:38:42 - Episode summary

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OptiCast - The Optimization Lab PodcastBy The Optimization Lab