According to some, weight loss is simply 2nd grade level math. Burn more energy than you eat, and fat is lost. Eat more energy than you burn, fat is gained—easy math, right? In this new show, we review how nutrient sensing enzymes that detect “energy balance” are also influenced by a range of non-nutritive factors, like hormones, inflammation and even oxygen levels. This show is brought to you by Fitcon.com An awesome live event occurring in Salt Lake City April 12th and 13th. http://fitcon.com Use coupon code HIH to save $50 off your ticket Link to show notes: https://highintensityhealth.com/261 Key Takeaways from this chat: 07:40: Hormones and energy balance are interconnected 08:30 mTOR as a primary energy sensor 09:51 How hormones influence & regulate energy switches 10:13 The anabolic vs catabolic balance (energy surpluses vs deficits) 10:52 How mTOR gets activated 11:51 Catabolic states, exercise and AMPK 12:40 Insulin, glucagon and malonyl-CoA: the triad that regulates fat synthesis and oxidation 14:10 The big picture of energy balance in the context of lifestyle change Link to show notes: https://highintensityhealth.com/261