Guest: Scott Newsome, DO, MSCS, FAAN 


The complexity and heterogeneity of multiple sclerosis (MS) pathogenesis renders its clinical course and response to therapy highly variable, particularly among special populations. This includes patients considering pregnancy or minority patients. This necessitates optimal strategies to personalize therapy and monitor disease activity and progression in special populations. This educational activity will review cutting-edge research on the unique considerations for prognosis, monitoring, and treatment response in special populations of MS patients. Focused attention will be given to translating research into optimized therapeutic strategies tailored to patient-specific characteristics with the goal of slowing disease progression. A compelling case study will be presented to illustrate clinically relevant challenges in disease management. Fee Information &amp; Refund/Cancellation Policy:There is no fee for this educational activity. To download the slide handouts for this presentation, please click here.

Case Challenges in MS: Tailoring Therapy to Patient-Specific Characteristics

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Host: Marc E. Agronin, MD 


  Guest: Richard S. Isaacson, MD 



  
    This series of bite-sized episodes contains important information you need to navigate the evolving world of Alzheimer’s disease (AD) research. Dr. Marc Agronin and Dr. Richard Isaacson discuss the recent advances in AD and provide practical approaches for prevention, diagnosis, and treatment.

Importance & Benefits of Early Diagnosis

Host: Barry A. Singer, MD 



  Patients living with MS can experience hidden or invisible symptoms that may not be apparent to others but can affect how they feel and function. In this podcast, Dr. Barry Singer, the Director at the Multiple Sclerosis Center for Innovations in Care, and Rosario, a patient who has been living with MS for 10 years, discuss their clinical and personal experiences with MS, and the impact that MS can have on a patient's QoL. In the 2-year AFFIRM pivotal trial: Relapsing MS patients received 300 mg TYSABRI every 28 days (n=627) or placebo (n=315). Patients with PPMS, SPMS, and PRMS were excluded.2,3 83% of patients taking TYSABRI had no sustained disability progression for 12 weeks vs 71% with placebo (primary endpoint: 17% vs 29%; p<0.001).2,3 Dr. Singer reviews the results of a recent publication from Hersh et al, which describes the effect of TYSABRI® (natalizumab) on various aspects of a patient’s QoL. In the study, 164 patients reported their experience after starting TYSABRI using a standard Quality of Life in Neurological Disorders (Neuro-QoL) assessment of 12 domains, which included anxiety, depression, positive affect and well-being, emotional and behavioral dyscontrol, stigma, cognitive function, sleep disturbance, fatigue, participation and satisfaction with social …

M.S. Perceptions: Candid HCP/Patient Clinical Conversations About MS

Host: Richard S. Isaacson, MD 


  Guest: Michael Weiner, MD 



  
    Are you familiar with available and developing tools for assessing Alzheimer’s disease (AD)? Correctly using these tools can lead to a vital earlier diagnosis which can improve outcomes for our patients. Tune in to hear Dr. Richard Isaacson and Dr. Michael Weiner take us through some of these assessment tools and they ways in which they can help us reach a true diagnosis of AD.

Alzheimer’s Disease: Tools for Early Diagnosis

Host: Jacqueline Nicholas, MD, MPH 



  Ever had a multiple sclerosis (MS) patient who needed to start a DMT? Listen to Dr. Jacqueline Nicholas, System Chief of Neuroimmunology and Director of MS Research at Ohio Health, and Kim, a patient who has been living with MS for seven years, share their experiences with the treatment decision process, including benefit-risk considerations, treatment goals, and patient preferences. They talk about the process for starting and continuing treatment with TYSABRI® (natalizumab) and how Biogen Support Services can help. Please see Important Safety Information, including Boxed Warning for PML, below.  

MSperceptions: Candid HCP/Patient Clinical Conversations about MS

Guest: Caroline Hastings, MD 


Guest: Raymond Y. Wang, MD 



  Niemann-Pick disease type C (NPC) is an ultra-rare, inherited, neurodegenerative disease with life-threatening complications. Due to its highly variable onset of neurological symptoms throughout one’s lifespan, recognizing and establishing diagnosis for NPC can be challenging for any clinician. That’s why Drs. Caroline Hastings and Raymond Y. Wang join Dr. Jennifer Caudle to help address those challenges with a detailed look at this genetic condition, the factors underlying its variable onset and course, and strategies to improve recognition, cross-specialty communications, and time to diagnosis.  Copyright ©2021 Orphazyme A/S. All rights reserved.NP-USA-1492-v1ORPHAZYME is a trademark or registered trademark of Orphazyme A/S.

Case Challenges in MS: Tailoring Therapy to Patient-Specific Characteristics

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