05.02.2022 - By Bret Weinstein & Heather Heying
Bret speaks with Alexandros Marinos, who has analyzed the TOGETHER trial, which aims to identify effective repurposed therapies to prevent the disease progression of COVID-19. Alexandros is the Founder/CEO of http://balena.io & aspiring practical philosopher. Find him on: https://twitter.com/alexandrosm https://doyourownresearch.substack.com/ Mentioned in this episode: https://www.togethertrial.com/ https://doyourownresearch.substack.com/p/the-problem-with-the-together-trial ***** Find Bret Weinstein on Twitter: @BretWeinstein, and on Patreon. https://www.patreon.com/bretweinstein Please subscribe to this channel for more long form content like this, and subscribe to the clips channel @DarkHorse Podcast Clips for short clips of all our podcasts: https://www.youtube.com/channel/UCAWCKUrmvK5F_ynBY_CMlIA All removed videos can be found on Spotify Video and Odysee: https://open.spotify.com/show/57R7dOcs60jUfOnuNG0J1R https://odysee.com/@BretWeinstein:f Check out the DHP store! Epic tabby, digital book burning, saddle up the dire wolves, and more: http://www.store.darkhorsepodcast.org Theme Music: Thank you to Martin Molin of Wintergatan for providing us the rights to use their excellent music. *****
Sign up for the Spectator at: https://spectatorworld.com/specialoffer/ Use code: DARKHORSE Farrow SkinFood is lard-based skincare that nourishes the skin without preservatives or added chemicals. Go to http://farrow.life/darkhorse for 20% off your first purchase; additional 15% off with a recurring subscription. ***** Timestamps: (00:00) Introduction (03:11) Better Skeptics project – analyzing COVID podcasts (08:12) TOGETHER trial and its timeline (15:35) Ads (19:08) Dosage & initial TOGETHER trial design (25:29) Confusing paper and placebo group dropout? (31:23) IVM dose too low and new protocol (35:04) Trial recruitment over time and key 10-week period (43:42) Systemic errors (51:33) Placebo arm from earlier period? (57:11) Trial data not being released (01:02:27) Exclusion criteria flipped (01:06:38) Hypothesis on algorithm rebalancing arms (01:13:35) Allocation to Fluvoxamine arm (01:17:12) TOGETHER trial authors believe IVM has an effect (01:20:15) Credible intervals and Bayesian statistics (01:25:55) Will we ever get the full story? (01:30:28) Dosing and weight limit (01:34:52) Background use of IVM in Brazil (01:47:19) “Independent” committee monitoring trial (01:54:29) Cavallo study and inconsistency in response (01:57:41) Press releases and cold confusion (02:09:27) Wrap up Support the show