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EMCrit 261 – Thrombolysis during Cardiac Arrest

12.12.2019 - By Scott D. Weingart, MD FCCMPlay

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Do you administer thrombolytics during cardiac arrest? Or maybe you don't believe in thrombolytics, but are totally down with fibrinolytics during arrest. Who do you administer them to and which one do you use? I give you my own circuitous ramblings on the topic in this episode.

Who Should Get Lysed?

SR/MA

* Wang et al.

RCT Mentioned

* TROICA (19092151)

Studies not Included in that SR/MA

* PEAPETT (27422214) (RebelM Review)

* French Registry Trial (31381884)

What Lytic?

Full Dose Tenecteplase via Manufacturer Recs or 50 mg of Alteplase by IV Push over ~60 seconds (29880524)

How Long Should You Keep Going?

* 30-60 minutes after lytic administration

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Thanks again!Fred and JF

Update

Evidence on the lack of utility of the RV during arrest to dx PE

Now on to the Podcast...

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