The endocannabinoid system can seem like a magical engine sometimes and, as cannabis enthusiasts, it's good to dig in and learn how it actually functions. On this episode of Shaping Fire, host Shango Los talks with cannabinoid scientist Miyabe Shields PhD about the chemical mechanics at the basis of our endocannabinoid system, including how cannabinoid receptors function, how cannabinoids take action, why we develop THC tolerance and how to manage it, and the effectiveness of whole plant versus single molecule cannabis medicine.

Endocannabinoid Mechanics Part One with guest Miyabe Shields PhD

Shaping Fire host Shango Los interviews the most knowledgable and insightful people in cannabis and entheogens. With topics ranging from cannabis cultivation, medicine and hashmaking, to healing humans with psychedelics.

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Nature

Some of the most potent psilocybin mushrooms have proven very difficult to cultivate indoors. These mushrooms love growing on hardwoods. On episode 113 of Shaping Fire, host Shango Los talks with mycologist Christian Kaelin about the attributes and personalities of wood-loving hallucinogenic mushrooms, how to find and wildcraft them, and how to build your own inoculated hardwood chip beds to cultivate them outdoors at home.

EP113 Wood Loving Psilocybin Mushrooms

Incredible cannabis plants start with soil diversity and thriving microbiology. During this episode of Shaping Fire, host Shango Los talks with microbiologist Michael DiLegge about natural biostimulants, the care and feeding of microbe life in your soil, choosing companion plants to encourage root zone diversity, and an indictment of the 24-hour light cycle theory.

EP112 Super-Charging Soil Microbiology with guest Michael DiLegge

Long Live Landraces! In this delightful introduction to cannabis landrace plant varieties, Shaping Fire host Shango Los talks with Santa Cruz landrace specialist Jade Nectar aka Jeff Nordahl about the differences between landrace, wild and feral varieties of cannabis, their unique attributes that attract connoisseurs, and the importance of conscious landrace breeding techniques and preservation.

EP111 Cannabis Landraces in Practice with guest Jade Nectar

Delta-8 THC is everywhere, but the scientific understanding of it is not. On this episode of Shaping Fire, host Shango Los welcomes back neuroscientist and renown cannabis researcher Dr. Ethan Russo to discuss the medicinal benefits of Delta-8 THC, its history, the challenges of synthesizing clean Delta-8 THC, and the negative impacts that synthetic Delta-8 THC is having throughout the cannabis community.

EP110 Delta-8 THC: The Troublesome Cannabinoid with guest Dr. Ethan Russo

Brain cells die, and our body has the ability to make new ones. But as we age, the ability to make new brain cells slows, and sometimes even slows so much that dementia arises. On this episode of Shaping Fire, host Shango Los, talks with cannabinoid researcher Staton Laws about the mechanics of neurogenesis, how cannabis medicine can stimulate the creation of vital neurons, and specific nootropic dosing protocols for those interested in sustaining their brain health and longevity, as well as cannabis patients who are already facing dementia and Alzheimer's disease.

Endocannabinoid Mechanics Part One with guest Miyabe Shields PhD

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