Retinoids are one of the most powerful tools in skincare—but they’re also one of the most misunderstood. In this episode, Dr. Dustin Portela and PA Austin Lee break down everything you need to know: the science behind how retinoids work, the real difference between retinol and tretinoin, how to build tolerance, and why consistent use matters more than strength.

They also dive into side effects (like dryness and “the purge”), debunk myths around skin thinning, and explain who shouldn’t use retinoids (hint: rosacea and pregnancy need special care). Plus, they introduce a new medical-grade retinol serum available through Dr. Portela’s office—designed for results with minimal irritation.

Stick around for a double dose of “Did You Know” trivia, practical starter tips, and advice on when (and if) you should level up to a stronger formula.

Follow Us: Dr. Portela TikTok: @drdustinportela Instagram: @drdustinportela YouTube (Reactions): @208SkinDoc YouTube (Educational): @drdustinportela Pinterest: @DrDustinPortela

Austin LeeTikTok: @austinleepac Instagram: @austinleepac