An overview of organic chemistry, beginning with a discussion of the nature of organic compounds, the history of vitalism and its influence on the development of organic chemistry, and what makes carbon so special. I then discuss some important concepts in organic chemistry, including IUPAC nomenclature, functional groups, aromaticity, fullerenes, polymers, and organic synthesis. Recommended prelistening is Episode 15: Chemical Bonding, and Episode 23: Chemical Reactions.