Startup and Nation

From Scientist to Startup Founder: Building the Virtual Cell for Drug Discovery | Natalie Ma, Deep Origin


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In this episode of Startup & Nation, we dive deep with Natalie Ma, co-founder and head of business development at Deep Origin. Natalie's journey from environmental science undergraduate to co-founding a startup is a fascinating tale of curiosity-driven transitions. We explore her path through a PhD in synthetic biology, frustrations with the slow application of academic research, and a fortuitous meeting that led her to startups. Natalie explains how Deep Origin aims to build a 'virtual cell' to reduce failures in drug discovery and development, discusses market validation for biotech startups, and elaborates on the importance of industry-academic collaboration. This insightful conversation covers the challenges of translating academic research to practical applications, the nuances of market needs, and the role AI could play in regulatory processes. Tune in to understand the dynamic world of biotech innovation and the human-centric approaches driving it forward.

00:00 Introduction to Natalie Ma and Deep Origin

01:30 Natalie's Journey from Academia to Industry

05:43 Challenges and Insights in Biotech Startups

11:56 Deep Origin's Mission and Innovations

19:33 Balancing Social Impact and Profit

23:44 Cultural and Practical Differences Between Academia and Industry

33:33 The Challenge of Valuing Research

34:39 Practical Problem-Solving in Academia

36:51 Bridging the Gap Between Academia and Industry

37:32 Teaching Open-Ended Questioning

40:35 The Role of AI in Research and Regulation

50:14 How to think about Public-Private Partnerships

53:35 Networking and Overcoming Social Anxiety

59:22 Final Thoughts and Call to Action

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Startup and NationBy Meng Fei Shen