In this episode, we break down cirrhosis using a clinically focused, high-yield framework. We review the pathophysiology of chronic liver injury leading to fibrosis, portal hypertension, and synthetic dysfunction, along with classic history and physical exam findings. The discussion highlights key laboratory and imaging clues, severity scoring with Child-Pugh and MELD, and essential management strategies for complications such as ascites, varices, hepatic encephalopathy, and spontaneous bacterial peritonitis. We also emphasize prevention, surveillance for hepatocellular carcinoma, and early transplant referral.

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