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In this episode, we review esophageal strictures, an abnormal narrowing of the esophageal lumen most commonly caused by chronic GERD. We break down the pathophysiology of inflammation leading to fibrosis and luminal narrowing, along with other important causes including caustic ingestion, radiation, eosinophilic esophagitis, and malignancy. The discussion highlights the classic presentation of progressive dysphagia to solids, appropriate use of barium swallow and endoscopy, and evidence-based management with endoscopic dilation. We also review red flags for malignancy and complications such as perforation.
References
1) Bushardt RL, Colomb-Lippa DM, Klinger AM, Reed H. The JAAPA QRS Review for PAs: Study Plan and Guide for PANCE and PANRE. 1st ed. LWW; 2021. ISBN: 9781975143817.
2) Pregun I, Hritz I, Tulassay Z, Herszényi L. Peptic esophageal stricture: medical treatment. Dig Dis. 2009;27(1):31-7. doi: 10.1159/000210101. Epub 2009 May 8. PMID: 19439958.
3) Yang F, Hu Y, Shi Z, Liu M, Hu K, Ye G, Pang Q, Hou R, Tang K, Zhu Y. The occurrence and development mechanisms of esophageal stricture: state of the art review. J Transl Med. 2024 Jan 31;22(1):123. doi: 10.1186/s12967-024-04932-2. PMID: 38297325; PMCID: PMC10832115.
4) Luedtke P, Levine MS, Rubesin SE, Weinstein DS, Laufer I. Radiologic diagnosis of benign esophageal strictures: a pattern approach. Radiographics. 2003 Jul-Aug;23(4):897-909. doi: 10.1148/rg.234025717. PMID: 12853664.
By Kristopher Maday, PA-C, DFAAPAIn this episode, we review esophageal strictures, an abnormal narrowing of the esophageal lumen most commonly caused by chronic GERD. We break down the pathophysiology of inflammation leading to fibrosis and luminal narrowing, along with other important causes including caustic ingestion, radiation, eosinophilic esophagitis, and malignancy. The discussion highlights the classic presentation of progressive dysphagia to solids, appropriate use of barium swallow and endoscopy, and evidence-based management with endoscopic dilation. We also review red flags for malignancy and complications such as perforation.
References
1) Bushardt RL, Colomb-Lippa DM, Klinger AM, Reed H. The JAAPA QRS Review for PAs: Study Plan and Guide for PANCE and PANRE. 1st ed. LWW; 2021. ISBN: 9781975143817.
2) Pregun I, Hritz I, Tulassay Z, Herszényi L. Peptic esophageal stricture: medical treatment. Dig Dis. 2009;27(1):31-7. doi: 10.1159/000210101. Epub 2009 May 8. PMID: 19439958.
3) Yang F, Hu Y, Shi Z, Liu M, Hu K, Ye G, Pang Q, Hou R, Tang K, Zhu Y. The occurrence and development mechanisms of esophageal stricture: state of the art review. J Transl Med. 2024 Jan 31;22(1):123. doi: 10.1186/s12967-024-04932-2. PMID: 38297325; PMCID: PMC10832115.
4) Luedtke P, Levine MS, Rubesin SE, Weinstein DS, Laufer I. Radiologic diagnosis of benign esophageal strictures: a pattern approach. Radiographics. 2003 Jul-Aug;23(4):897-909. doi: 10.1148/rg.234025717. PMID: 12853664.