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Gastrointestinal - Portal Hypertension
In this episode, we break down portal hypertension with a clear, clinically focused approach. We review the hemodynamic basis of elevated portal pressure, the development of portosystemic collateral circulation, and the classic signs such as splenomegaly, ascites, and varices. The discussion highlights diagnostic strategies, including Doppler ultrasound and endoscopic screening, and emphasizes evidence-based management to prevent variceal bleeding and treat complications.
References
1) Bushardt RL, Colomb-Lippa DM, Klinger AM, Reed H. The JAAPA QRS Review for PAs: Study Plan and Guide for PANCE and PANRE. 1st ed. LWW; 2021. ISBN: 9781975143817.
2) García-Pagán JC, Gracia-Sancho J, Bosch J. Functional aspects on the pathophysiology of portal hypertension in cirrhosis. J Hepatol. 2012 Aug;57(2):458-61. doi: 10.1016/j.jhep.2012.03.007. Epub 2012 Apr 12. PMID: 22504334.
3) Berzigotti A, Seijo S, Reverter E, Bosch J. Assessing portal hypertension in liver diseases. Expert Rev Gastroenterol Hepatol. 2013 Feb;7(2):141-55. doi: 10.1586/egh.12.83. PMID: 23363263.
4) Tapper EB, Parikh ND. Diagnosis and Management of Cirrhosis and Its Complications: A Review. JAMA. 2023 May 9;329(18):1589-1602. doi: 10.1001/jama.2023.5997. PMID: 37159031; PMCID: PMC10843851.
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By Kristopher Maday, PA-C, DFAAPAIn this episode, we break down portal hypertension with a clear, clinically focused approach. We review the hemodynamic basis of elevated portal pressure, the development of portosystemic collateral circulation, and the classic signs such as splenomegaly, ascites, and varices. The discussion highlights diagnostic strategies, including Doppler ultrasound and endoscopic screening, and emphasizes evidence-based management to prevent variceal bleeding and treat complications.
References
1) Bushardt RL, Colomb-Lippa DM, Klinger AM, Reed H. The JAAPA QRS Review for PAs: Study Plan and Guide for PANCE and PANRE. 1st ed. LWW; 2021. ISBN: 9781975143817.
2) García-Pagán JC, Gracia-Sancho J, Bosch J. Functional aspects on the pathophysiology of portal hypertension in cirrhosis. J Hepatol. 2012 Aug;57(2):458-61. doi: 10.1016/j.jhep.2012.03.007. Epub 2012 Apr 12. PMID: 22504334.
3) Berzigotti A, Seijo S, Reverter E, Bosch J. Assessing portal hypertension in liver diseases. Expert Rev Gastroenterol Hepatol. 2013 Feb;7(2):141-55. doi: 10.1586/egh.12.83. PMID: 23363263.
4) Tapper EB, Parikh ND. Diagnosis and Management of Cirrhosis and Its Complications: A Review. JAMA. 2023 May 9;329(18):1589-1602. doi: 10.1001/jama.2023.5997. PMID: 37159031; PMCID: PMC10843851.