HelixTalk - Rosalind Franklin University's College of Pharmacy Podcast

By Sean P. Kane, PharmD; Khyati Patel, PharmD

What's HelixTalk - Rosalind Franklin University's College of Pharmacy Podcast about?

This podcast is produced by pharmacy faculty to supplement study material and provide relevant drug and professional topics. We're hoping that our real-life clinical pearls and discussions will help you stay up-to-date and improve your pharmacy knowledge.

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HelixTalk - Rosalind Franklin University's College of Pharmacy Podcast episodes:

04.16.2024
181 - From Meds to Machine Learning: How AI is (and will) Revolutionizing Pharmacy Practice
In this episode, we discuss artificial intelligence large language models (LLMs) and how these will impact the future of the practice of pharmacy. Key Concepts Generative AI with large language models (LLMs) have already changed how healthcare is delivered...
03.26.2024
180 - The Ultimate Guide to Statins: An In-Depth Drug Class Review
In this episode, we review the pharmacology, indications, adverse effects, monitoring, and unique drug characteristics of HMG CoA reductase inhibitors (“statins”). Key Concepts Statins reduce LDL cholesterol by 20-60% (depending on the dose and statin potency). They have modest...
03.05.2024
179 - Annual Dose of Sweetness: 2024 Updates from the American Diabetes Association Guidelines
In this recurring episode, we discuss the important updates from the 2024 American Diabetes Association Guidelines! Key Concepts Tirzepatide is now recommended as one of the weight loss pharmacotherapy options along with semaglutide in patients with diabetes. The language...
02.13.2024
178 - Law & Order: Pharmacy Edition. A Concise Review of High-Yield Pharmacy Law Topics for the MPJE
In this episode, we speak with Janeen Winnike, the Associate Dean for Student Affairs at Rosalind Franklin and a co-course director for the Pharmacy Law course at the university. We review some of the key points regarding federal and Illinois...
01.23.2024
177 - The Antidote Arsenal: Exploring the Emergency Toolbox for Anticoagulant Reversals
In this episode, we review evidence-based guidelines for the emergency reversal of warfarin, dabigatran, and the oral Xa inhibitors (apixaban, edoxaban, and rivaroxaban). Key Concepts Reversal of anticoagulation is indicated in patients with major hemorrhage or when emergency surgery...
01.02.2024
176 - Hormonal Harmony: A Pharmacist’s Guide to Hormonal Contraceptives (Part 2)
In this two part episode, we review some of the most important clinical pearls in the pharmacotherapy and practice aspects of hormonal contraceptives with a brief focus on the very first FDA approved OTC hormonal contraceptive product (Opill). Key Concepts...
12.13.2023
175 - Hormonal Harmony: A Pharmacist’s Guide to Hormonal Contraceptives (Part 1)
In this two part episode, we review some of the most important clinical pearls in the pharmacotherapy and practice aspects of hormonal contraceptives with a brief focus on the very first FDA approved OTC hormonal contraceptive product (Opill). Key Concepts...
12.04.2023
174 - Finding Your Mount Rushmore: The Journey of an Industry Pharmacist
In this episode, we interview Scott Glosner, PharmD, MPH, BCPS about his extensive experience working at Pfizer in medical outcomes and as a field medical director. Dr. Glosner will share his career journey from a clinical pharmacist transitioning into the...
10.31.2023
173 - Balancing Access and Safety: The FDA's Prescription Drug Risk Mitigation Strategy (REMS)
In this episode, we will discuss the definition of REMS (Risk Evaluation and Mitigation Strategies), why they exist, the role of FDA in administering REMS, types and examples of REMS, and how they impact pharmacy practice. Key Concepts The...
10.10.2023
172 - Battle of the Clot Busters: Alteplase vs. Tenecteplase for Acute Ischemic Stroke
In this episode, we review the role and indications of thrombolytics in acute ischemic stroke. The efficacy, safety, administration considerations, and cost between alteplase and tenecteplase are compared and contrasted. Key Concepts Alteplase (Activase) is a recombinant DNA version...
09.19.2023
171 - Two Vax’s and a MAB: What’s New in RSV Prevention
In this episode, we briefly review RSV (respiratory syncytial virus) infections and focus on new data supporting the use of two different RSV vaccines (Abrysvo and Arvexy) in preventing RSV infections in older adults and in pregnant women. Key Concepts...
08.29.2023
170 - Hope and Healing: Overcoming Opioid Use Disorder Through Evidence-Based Therapies
In this episode, together with our faculty colleague, Dr. Roberta Dume, PharmD, BCPP, we discuss the pharmacologic options and evidence for the treatment of opioid use disorder (OUD) and how pharmacists play a vital role in assisting patients suffering from...
08.08.2023
169 - Introducing HelixTalk’s 2023 Drug Superlative Awards!
In this episode, we announce the second iteration of the HelixTalk Drug Superlative Awards -- awards given to medications on the market that are outstanding or notorious. In announcing these completely fictitious awards, we review key clinical pearls and pitfalls...
07.18.2023
168 - Beyond the Controversy: Exploring Efficacy and Safety of Medication Abortion
There has been a lot of news about abortion (abortifacient) medications recently. Since the overturn of Roe v. Wade in 2022, individual states passed their own laws restricting access to abortion, this includes access to abortion medications. This clearly impacts...
06.27.2023
167 - Beyond One-Size-Fits-All: Unraveling the Genetic Tapestry of CYP2D6 Drug Metabolism
In this episode, we review the science behind genetic differences in humans in the CYP2D6 hepatic enzyme responsible for drug metabolism and how these genetic variants can lead to certain drugs being metabolized far too much or far too little,...
06.06.2023
166 - Thiazide Throwdown: Hydrochlorothiazide vs. Chlorthalidone - The Ultimate Showdown for Hypertension Management
In this episode, we compare hydrochlorothiazide and chlorthalidone, but specifically from a cardiovascular outcomes perspective when used in patients with hypertension. Key Concepts Chlorthalidone, hydrochlorothiazide, and indapamide are available thiazide diuretics for treatment of hypertension; however, hydrochlorothiazide is the...
05.16.2023
165 - QT and the Beast: Managing Medications That Prolong the QT Interval
In this episode, we discuss the concerns of QTc prolongation, which can cause a fatal arrhythmia called torsades de pointes (TdP). We cover the difference between QT and QTc, how to interpret a QTc (and when it is inaccurate), common...
04.25.2023
164 - Breaking Down the Updates: Key Changes and Implications of the 2023 American Diabetes Association Guidelines
In this episode, we will discuss the most important updates from the American Diabetes Association’s 2023 Standards of Care in Diabetes. Key Concepts The first-line therapy for type II diabetes is based on whether the primary goal of therapy...
04.04.2023
163 - The Two-Drug Tango: A Concise Guide to Tacrolimus and Mycophenolate in Organ Transplantation
In this episode, we review clinical pearls and common pitfalls of immunosuppression regimens for organ transplantation with a particular focus on tacrolimus and mycophenolate. Key Concepts Most recipients of an organ transplantation will be on a two or three...
03.14.2023
162 - A1C You Later: A Concise Review of Continuous Glucose Monitors for the Practicing Pharmacist
In this first ever CE episode, we discuss the A-Zs of continuous glucose monitors (CGMs). In specific, our learning objective for the CE are: Describe commonly available types of continuous glucose monitors (CGMs) in the US market and...
02.21.2023
161 - My Loss Is Your Gain! How Drug Repository Programs Are Helping Patients Afford High-cost Medications
In this episode, we interview Dr. Shannon Rotolo and Dr. Alex Berce regarding Illinois and Wisconsin drug repository programs – these are programs that allow certain medications to be donated to participating sites and then redistributed to patients at a...
01.31.2023
160 - Dextromethorphan for Depression? Analyzing Data for Auvelity® in Major Depressive Disorder
In this episode, we discuss the evidence, safety, and place in therapy of Auvelity® (dextromethorphan-bupropion), a newly approved antidepressant with a unique mechanism of action and interesting pharmacokinetic considerations. Key Concepts Auvelity® (bupropion-dextromethorphan) was FDA approved in 2022 for...
01.10.2023
159 - A Breath of Fresh Air: Big Changes to the 2023 GOLD Guidelines for COPD
In this episode, we highlight important changes to the 2023 GOLD Guidelines for COPD. In particular, we discuss a revision to the GOLD group classification system and the preferred initial therapies in patients with COPD. Key Concepts The newest...
12.21.2022
158 - PADing Your Understanding of Peripheral Arterial Disease: A Brief Treatment Overview
In this episode, we will discuss all things peripheral arterial disease – definitions, staging, clinical presentation, risk factors, goals of therapy, and guideline-directed medication therapy recommendations including the newest evidence for the use of DOACs. Key Concepts Addressing modifiable...
11.29.2022
157 - Everything Will Be ao-K+: Potassium Formulations and Dosing for Hypokalemia
In this episode, we review the management of a patient with hypokalemia, including both inpatient and outpatient supplementation with potassium chloride supplements and what dosage forms are available for potassium repletion. Key Concepts Most diets will provide sufficient potassium...
11.08.2022
156 - There Is an App for That: Digital Health Advancements and More!
In this episode, we will define Digital Health, its categories and examples, describe how pharmacists are involved in DH practice, opportunities and limitations and future of DH. We will also discuss what implications DH has for educators, educational institutions, student...
10.18.2022
155 - Oncology 911: Tumor Lysis Syndrome as an Oncologic Emergency
In this episode, we invite Dr. Amir Ali, PharmD, BCOP to discuss with us the pathophysiology, risk factors, prevention, and treatment clinical pearls of tumor lysis syndrome TLS). Key Concepts TLS is caused by rapid cell death of cancerous...
09.27.2022
154 - What’s New With Paxlovid: Drug Interactions, Pharmacist Prescribing, “Paxlovid Mouth”, and a Brief Drug Review
In this episode, we review Paxlovid (nirmatrelvir/ritonavir) from the perspective of its pharmacology, efficacy, safety, pharmacists’ authority to prescribe, drug interactions, and rebound symptoms after Paxlovid therapy. Key Concepts Paxlovid is the preferred outpatient therapy for COVID-19 in patients...
09.06.2022
153 - Buy One Get One Free: Learning All about the Dual Acting GIP and GLP-1 Receptor Agonist
In this episode, we will discuss mechanism, pharmacokinetics, efficacy, safety, and possible place in therapy for tirzepatide (Mounjaro), a new treatment for type 2 diabetes. Key Concepts Tirzepatide is a novel GIP and GLP-1 receptor agonist resulting in glucose-dependent...
08.16.2022
152 - Strain-ger Things: Pneumococcal Vaccine Updates
In this episode, we will discuss the rationale behind the FDA approval of two new pneumococcal conjugate vaccines (PCV20 and PCV15), the characteristics of these vaccines, their place in therapy as recommended by the ACIP, and subsequent CDC immunization schedule...
07.26.2022
151 - Deep Dive into Diltiazem: Pharmaceutics, Medicinal Chemistry, the FDA Orange Book, and More!
In this episode, we “deep dive” into diltiazem, describing its most important drug facts, pharmacology and medicinal chemistry, pharmaceutics, AB compatibility, and important medication safety issues. Key Concepts Diltiazem is a non-dihydropyridine calcium channel blocker (CCB). This type of...
07.05.2022
150 - Keep on Going Strong: A Reflection of 150 HelixTalk Episodes Through the Years
In this episode, the hosts of the HelixTalk reflect back on the history and making of HelixTalk to commemorate the 150th episode. We review each of our three favorite episodes and with a brief reflection on the episode content. We...
06.14.2022
149 - Replenishing the Missing Element: A Complete Review of Iron Deficiency Anemia
In this episode, we will cover a complete overview of definition, diagnosis, treatment and monitoring of iron deficiency anemia (IDA). Key Concepts Iron-deficiency anemia (IDA) is the most common type of nutritional anemia. The most common risk factors are...
05.24.2022
148 - Grit, Determination, and Entrepreneurship: A Pharmacist’s Career Path to Starting an Independent Pharmacy
In this episode, we interview Hetal Patel, PharmD and RFUMS COP Alumni, regarding her career path that eventually led her to open Lebanon Family Pharmacy in TN in 2021. We discuss the challenges and opportunities of starting a new independent...
05.03.2022
147 - Key Recommendations from the 2022 AHA/ACC/HFSA Heart Failure Guidelines
In this episode, we review new updates and key concepts from the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure. This guideline is newly published (April 2022) and is a full update of the 2013 guidelines and the 2017...
04.12.2022
146 - New Drugs for Bad Bugs: Six Newer Antibiotics for Multidrug Resistant Pathogens
In this episode, we discuss six newer antibiotics that target multidrug resistant gram negative bacteria with Dr. Christie Bertram, PharmD, BCIDP. We review common resistance mechanisms, particularly to carbapenems, and highlight the current role in therapy for the following antibiotics:...
03.22.2022
145 - Advancing the Profession: Contraceptive Prescribing by Pharmacists in Illinois
In this episode, we bring in two guests to discuss the impact of professional advocacy and resulting professional advancements in the state of Illinois. These guests were the front-line agents of advocacy which resulted in pharmacists' ability to prescribe hormonal...
03.01.2022
144 - mRNA Technologies and their Implications in Therapeutics: Q&A with Dr. Martin
In this episode, we interview Dr. Danyelle Martin, a Medical Science Liaison (MSL) at Moderna, in order to learn more about the what, how, and future of mRNA-based therapeutics, and what impact it can have on healthcare and healthcare professionals...
02.08.2022
143 - The Low Down on Hypothyroidism: The Essentials of What Healthcare Providers Need to Know
In this episode, we review the diagnostic criteria and treatment strategy of hypothyroidism including the controversy surrounding brand versus generic levothyroxine and non-levothyroxine thyroid drugs. Key Concepts The most common cause of hypothyroidism is autoimmune thyroiditis - the body...
01.18.2022
142 - New Gains in Weight Loss Pharmacotherapy
In this episode, we will build up on our previous Weight loss Pharmacotherapy Episode, episode #13 to discuss updates in guidelines, prevention of obesity from comorbidity standpoint, and new treatment agents for weight-loss with a particular focus on Contrave (naltrexone/bupropion),...
12.28.2021
141 - What You Need to Know about Hepatorenal Syndrome: New Definitions, Treatments, and Clinical Pearls
In this episode, we provide a concise overview of the diagnosis and treatment of hepatorenal syndrome-acute kidney injury (HRS-AKI) with a focus on the new HRS-1 definition (now called HRS-AKI), new data with terlipressin, and the AASLD 2021 guidelines. Key...
12.07.2021
140 - The Ultimate Guide to SSRIs: An In-Depth Drug Class Review
In this episode, we review the pharmacology, indications, adverse effects, and unique drug characteristics of the most common SSRIs on the market. Key Concepts SSRIs (selective serotonin reuptake inhibitors) are the drug of choice for depression, anxiety, and a...
11.16.2021
139 - They Did What?! FDA Approval of Aducanumab for Alzheimer’s Disease
In this episode, we discuss the recent accelerated approval of the new monoclonal antibody-based treatment agent, aducanumab (Aduhelm), by the FDA. We dive into the drug approval process, the efficacy and safety data, and the behind-the-scenes story of the FDA...
10.26.2021
138 - Hidden Pharmaceutics: The Fascinating Science Behind Dosage Formulations
In this episode, we discuss the fascinating science of pharmaceutics with Dr. Kristen Ahlschwede and Dr. Rahul Deshmukh. We explore how dosage forms and excipients play an important role in how a drug product behaves in the human body with...
10.05.2021
137 - It’s Time for PBM Reform: How PBMs Have Hurt Pharmacies and Increased Drug Costs
In this episode, we reveal what goes on behind the scenes for drug pricing and pharmacy reimbursement with Dr. Benjamin Jolley. Our discussion covers important concepts like PBMs, DIR fees, MAC pricing, and even possible upcoming changes at the federal...
09.14.2021
136 - Major Recommendations from the 2021 CHEST Anticoagulation for VTE Disease Guideline Updates
In this episode, we discuss the recently published major updates in the 9th edition of the anticoagulation guidelines from CHEST. These new recommendations range from initiation of therapy, secondary prevention, and management of post-thrombotic syndrome. Key Concepts Among patients...
08.24.2021
135 - Top Four Medications Myths: BUSTED!
In this episode, we debunk four medication myths that have persisted for decades: metronidazole and alcohol; statins and hepatotoxicity; cidal vs. static antibiotics; and "sulfa" allergies. Key concepts Metronidazole does not interact with alcohol (ethanol) and does not cause...
08.03.2021
134 - Hypertensive Emergencies Demystified: A Brief Clinical Review
In this episode, we provide a concise review of the diagnostic criteria and general treatment approach to patients with hypertensive emergencies. Key Concepts Hypertensive “urgency” is a misnomer - patients do not require immediate therapy and definitely should not...
07.13.2021
133 - Tell Me More: Exploring Covid 19 Vaccine Hesitancy and Solutions!
In this episode, we will explore depths of COVID 19 vaccine hesitancy - what it is, how to identify and address it, and some helpful resources. Key Concepts When a patient seems hesitant to consider the COVID-19 vaccine, explore...
06.22.2021
132 - The Warp Speed of Covid-19 Vaccine Authorizations: Timeline and Discussion with Dr. Archana Chatterjee
In this episode, we will explore the history of COVID vaccine development and have a heart-to-heart conversation with Dr. Archana Chatterjee regarding her role as a dean of the RFUMS Chicago Medical School, her career path, and her position and...

What's HelixTalk - Rosalind Franklin University's College of Pharmacy Podcast about?

Download our free app to listen on your phone

HelixTalk - Rosalind Franklin University's College of Pharmacy Podcast episodes:

181 - From Meds to Machine Learning: How AI is (and will) Revolutionizing Pharmacy Practice

180 - The Ultimate Guide to Statins: An In-Depth Drug Class Review

179 - Annual Dose of Sweetness: 2024 Updates from the American Diabetes Association Guidelines

178 - Law & Order: Pharmacy Edition. A Concise Review of High-Yield Pharmacy Law Topics for the MPJE

177 - The Antidote Arsenal: Exploring the Emergency Toolbox for Anticoagulant Reversals

176 - Hormonal Harmony: A Pharmacist’s Guide to Hormonal Contraceptives (Part 2)

175 - Hormonal Harmony: A Pharmacist’s Guide to Hormonal Contraceptives (Part 1)

174 - Finding Your Mount Rushmore: The Journey of an Industry Pharmacist

173 - Balancing Access and Safety: The FDA's Prescription Drug Risk Mitigation Strategy (REMS)

172 - Battle of the Clot Busters: Alteplase vs. Tenecteplase for Acute Ischemic Stroke

171 - Two Vax’s and a MAB: What’s New in RSV Prevention

170 - Hope and Healing: Overcoming Opioid Use Disorder Through Evidence-Based Therapies

169 - Introducing HelixTalk’s 2023 Drug Superlative Awards!

168 - Beyond the Controversy: Exploring Efficacy and Safety of Medication Abortion

167 - Beyond One-Size-Fits-All: Unraveling the Genetic Tapestry of CYP2D6 Drug Metabolism

166 - Thiazide Throwdown: Hydrochlorothiazide vs. Chlorthalidone - The Ultimate Showdown for Hypertension Management

165 - QT and the Beast: Managing Medications That Prolong the QT Interval

164 - Breaking Down the Updates: Key Changes and Implications of the 2023 American Diabetes Association Guidelines

163 - The Two-Drug Tango: A Concise Guide to Tacrolimus and Mycophenolate in Organ Transplantation

162 - A1C You Later: A Concise Review of Continuous Glucose Monitors for the Practicing Pharmacist

161 - My Loss Is Your Gain! How Drug Repository Programs Are Helping Patients Afford High-cost Medications

160 - Dextromethorphan for Depression? Analyzing Data for Auvelity® in Major Depressive Disorder

159 - A Breath of Fresh Air: Big Changes to the 2023 GOLD Guidelines for COPD

158 - PADing Your Understanding of Peripheral Arterial Disease: A Brief Treatment Overview

157 - Everything Will Be ao-K+: Potassium Formulations and Dosing for Hypokalemia

156 - There Is an App for That: Digital Health Advancements and More!

155 - Oncology 911: Tumor Lysis Syndrome as an Oncologic Emergency

154 - What’s New With Paxlovid: Drug Interactions, Pharmacist Prescribing, “Paxlovid Mouth”, and a Brief Drug Review

153 - Buy One Get One Free: Learning All about the Dual Acting GIP and GLP-1 Receptor Agonist

152 - Strain-ger Things: Pneumococcal Vaccine Updates

151 - Deep Dive into Diltiazem: Pharmaceutics, Medicinal Chemistry, the FDA Orange Book, and More!

150 - Keep on Going Strong: A Reflection of 150 HelixTalk Episodes Through the Years

149 - Replenishing the Missing Element: A Complete Review of Iron Deficiency Anemia

148 - Grit, Determination, and Entrepreneurship: A Pharmacist’s Career Path to Starting an Independent Pharmacy

147 - Key Recommendations from the 2022 AHA/ACC/HFSA Heart Failure Guidelines

146 - New Drugs for Bad Bugs: Six Newer Antibiotics for Multidrug Resistant Pathogens

145 - Advancing the Profession: Contraceptive Prescribing by Pharmacists in Illinois

144 - mRNA Technologies and their Implications in Therapeutics: Q&A with Dr. Martin

143 - The Low Down on Hypothyroidism: The Essentials of What Healthcare Providers Need to Know

142 - New Gains in Weight Loss Pharmacotherapy

141 - What You Need to Know about Hepatorenal Syndrome: New Definitions, Treatments, and Clinical Pearls

140 - The Ultimate Guide to SSRIs: An In-Depth Drug Class Review

139 - They Did What?! FDA Approval of Aducanumab for Alzheimer’s Disease

138 - Hidden Pharmaceutics: The Fascinating Science Behind Dosage Formulations

137 - It’s Time for PBM Reform: How PBMs Have Hurt Pharmacies and Increased Drug Costs

136 - Major Recommendations from the 2021 CHEST Anticoagulation for VTE Disease Guideline Updates

135 - Top Four Medications Myths: BUSTED!

134 - Hypertensive Emergencies Demystified: A Brief Clinical Review

133 - Tell Me More: Exploring Covid 19 Vaccine Hesitancy and Solutions!

132 - The Warp Speed of Covid-19 Vaccine Authorizations: Timeline and Discussion with Dr. Archana Chatterjee