This week we tackle the topic of tucatinib in HER2-positive breast cancer with brain metastases. We also interview Dr. Cailin O'Connor of the University of California Irvine on her research on misinformation and disinformation. We discuss her recent article in the Boston Review, titled "Hydroxychloroquine and the Political Polarization of Science", as well as her extensive body of work.

HER2CLIMB: doi.org/10.1200/JCO.20.00775
Hydroxychloroquine: http://bostonreview.net/science-nature-politics/cailin-oconnor-james-owen-weatherall-hydroxychloroquine-and-political
The Dynamics of Retraction in Epistemic Networks: http://philsci-archive.pitt.edu/17088/
How Misinformation Spreads: https://www.scientificamerican.com/article/how-misinformation-spreads-and-why-we-trust-it/

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2.56 HER2CLIMB & Misinformation and Disinformation with Dr. Cailin O'Connor

A podcast on medicine, oncology, & health policy. 
Host: Vinay Prasad, MD MPH from University of California San Francisco.
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Science & Medicine

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Medicine

Patient advocates, Pharma funding, and is MRD a suitable endpoint

Patient advocates funded by Pharma

FDA makes MRD the basis for AA

Another flawed quality metric. Reviewing the NEJM paper "Beta-Blockers After Myocardial Infarction and Preserved Ejection Fraction".

2.56 HER2CLIMB & Misinformation and Disinformation with Dr. Cailin O'Connor

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