Stay Current in Pediatric Surgery

Intestinal Rehabilitation Episode 5: Literature Review


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We’re back with a new episode from the intestinal rehabilitation center at Cincinnati Children’s Hospital.
This time we’re talking about peptides that enteroendocrine cells secretes with Drs. Helmrath and Wales.
Hosts: Ellen Encisco, Cecilia Gigena
Articles for further reading:
Safety and Efficacy of Teduglutide in Pediatric Patients with Intestinal Failure due to Short Bowel Syndrome: A 24-Week, Phase III Study.
https://aspenjournals.onlinelibrary.wiley.com/doi/full/10.1002/jpen.1690
Outcomes from a 12-Week, Open-Label, Multicenter Clinical Trial of Teduglutide in Pediatric Short Bowel Syndrome.
https://pubmed.ncbi.nlm.nih.gov/27855998/
Experience With Teduglutide in Pediatric Short Bowel Syndrome: First Real-life Data
https://pubmed.ncbi.nlm.nih.gov/32804906/
Enteroendocrine cells couple nutrient sensing to nutrient absorption by regulating ion transport. https://www.nature.com/articles/s41467-020-18536-z
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