Immune checkpoint inhibitors have been a major breakthrough in cancer treatment but can have many serious adverse effects. Pankti Reid, MD, MPH, assistant professor of medicine in rheumatology at the University of Chicago, discusses the pathogenesis, diagnosis, and treatment of toxicities from immune checkpoint inhibitors as outlined by the 2019 NCCN guidelines. Related Article:  Management of Immunotherapy-Related Toxicities in Patients Treated With Immune Checkpoint Inhibitor Therapy

Management of Immunotherapy-Related Toxicities

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Dislocated hips in newborns can lead to complex surgery, interruption to family life, and premature osteoarthritis. Daniel Perry, MBChb(Hons), PhD, of Alder Hey Children's Hospital, University of Liverpool, discusses the clinical diagnosis of dislocated hips in newborns with JAMA Associate Editor David Simel, MD, MHS.  Related Content:  Does This Infant Have a Dislocated Hip? 

Clinical Diagnosis of Dislocated Hips in Newborns

Systemic lupus erythematosus (SLE) can present at any age and is associated with immune-mediated damage to multiple organs and increased rates of cardiovascular disease, cancer, and disability. New treatments have been FDA approved. Caroline H. Siegel, MD, MS, discusses this and more with JAMA Deputy Editor Mary McGrae McDermott, MD.  Related Content:  Systemic Lupus Erythematosus 

Diagnosis and Treatment of Systemic Lupus Erythematosus

Falls are common in adults older than 65 years and can cause substantial morbidity and mortality. JAMA Associate Editor David Simel, MD, MHS, discusses risk assessment and prevention of falls in older adults with Karin E. Ouchida, MD, of Weill-Cornell Medical University, and author Cathleen Colon-Emeric, MD, of Duke University.  Related Content:  Risk Assessment and Prevention of Falls in Older Community-Dwelling Adults Falls Prevention for Older Adults 

Falls in Community-Dwelling Older Adults

Dry mouth, oral candidiasis, and recurrent aphthous ulcers are common oral conditions that may be associated with patient discomfort, decreased quality of life, and in some cases, morbidity. Author Eric T. Stoopler, DMD, of Penn Dental Medicine, discusses these 3 common oral conditions with JAMA Associate Editor David L. Simel, MD, MHS.  Related Content:  Common Oral Conditions 

Diagnoses and Treatment of Common Oral Conditions

Interview with James Stevermer, MD, MSPH, USPSTF member and coauthor of Primary Care Interventions to Prevent Child Maltreatment: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.  Related Content:  Primary Care Interventions to Prevent Child Maltreatment Primary Care Interventions to Prevent Child Maltreatment Interventions to Prevent Child Maltreatment Struggling to Stem the Tide of Child Maltreatment 

Management of Immunotherapy-Related Toxicities

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