Activating Hope

Mission, Momentum, and Meaning: The Realities of Leading a Nonprofit Today with DeVone Holt


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In this episode of Activating HOPE, we take an honest and hopeful look at what it truly means to lead a nonprofit in today’s complex world. This conversation explores the passion that fuels nonprofit leaders—and the pressures that come with the job.

Our guest, DeVon Holt, brings a wealth of experience and insight to the table as we unpack both the inspiring opportunities and tough challenges of mission-driven leadership. From navigating resource constraints and stakeholder expectations to staying anchored in purpose amid constant change, we’ll explore what it takes to lead with clarity, resilience, and heart.

DeVone Holt is a powerhouse of purpose-driven leadership. With nearly 30 years of experience as a brand builder, culture shaper, strategic communicator, and people convener, DeVone brings a rare combination of vision and execution to everything he touches.

In 2024, he was named President and CEO of the Muhammad Ali Center in Louisville, a 96,000-square-foot cultural institution dedicated to preserving and advancing the legacy of "The Greatest"—a legacy rooted in service, justice, and courage.

Before stepping into this role, DeVone served as Chief External Affairs Officer at Goodwill Industries of Kentucky, where he led the transformation of a 20-acre brownfield site into a $120 million Opportunity Campus—complete with the area's first full-service hospital in over a century and Kentucky’s first high school for adults, a bold initiative he personally championed.

His career spans leadership roles in education, workforce development, and economic revitalization. From attracting $400 million in urban business investments to co-founding a consulting firm that helped companies invest in inner-city communities, DeVone’s impact is far-reaching. He’s also the author of the best-selling book Hip-Hop Slop, a former radio host, and a recipient of an honorary doctorate from Simmons College of Kentucky for his work revitalizing underserved neighborhoods.

DeVone is a proud husband and father of two future leaders—and today, he joins us to talk about legacy, leadership, and what it truly means to activate hope.

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