Osteosarcoma is a relatively rare but feared disease. What exactly is an osteosarcoma and how should it be worked up and treated? Host Dr. Lee Freedman discusses this diagnosis with Dr. Kristy Weber, Abramson Family Professor in Sarcoma Care Excellence and Professor, Vice-Chair of Faculty Affairs, Department of Orthopaedic Surgery; Director of the Sarcoma Program, Abramson Cancer Center; Chief, Orthopaedic Oncology.