Today, we’re sharing an episode of a show we love: Not Past It. ​​Did you know there was almost an AIDS vaccine? On June 3, 1998, AIDSVAX VAX004 reached the final stage of trials before widespread approval. Not Past It host Simone Polanen gets the facts on the vax and why it never made it to the masses.
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Presenting Not Past It: The Vax That Got Axed

There are a lot of fads, blogs and strong opinions, but then there’s SCIENCE. Science Vs is the show from Gimlet that finds out what’s fact, what’s not, and what’s somewhere in between. We do the hard work of sifting through all the science so you don't have to and cover everything from 5G and Pandemics, to Vaping and Fasting Diets.

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It’s 1849, and a gruesome murder has just happened at Harvard. As body parts turn up, the science of the day is put to the ultimate test to find out: who committed this brutal killing? Prof. Paul Collins tells us how this morbid mystery unfolds.  

﻿Find our transcript here: https://bit.ly/ScienceVsMurderInTheIvoryTower

In this episode, we cover:
(00:00) The murder that shocked Harvard
(02:35) A very rich man disappears
(06:08) The tea chest of horrors
(07:34) The professor
(09:33) The janitor
(12:00) The case against the professor 
(14:25) The trial
(17:48) 1800s forensics enter the picture
(25:29) The verdict

This episode was produced by Kaitlyn Sawrey with help from Wendy Zukerman, Rose Rimler, Meryl Horn and Odelia Rubin. Editing by Blythe Terrell, with help from Caitlin Kenney. Fact checking by Michelle Harris. Mix and sound design by Emma Munger. Music by Emma Munger and Bobby Lord. A huge thanks to Jessica Murphy and the team at the Harvard University Archives, plus Lars Trembly and Matthew Nelson, Frank Lopez, Joseph Lavelle Wilson and the Zukerman Family.

Science Vs is a Spotify Studios Original. Listen for free on Spotify or wherever you get your podcasts. Follow us and tap the bell for episode notifications. 

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Murder in the Ivory Tower

Weed has gone mainstream, and it's been rebranded as a wellness drug that you can customize to fit your needs. Want to feel relaxed? Well, you'll need a kind of pot called Indica. Want to get pepped up? Go for Sativa. But what can weed really do for us? We’re going to pack a bowl full of science facts, sit back, put our feet up and find out: Can cannabis really improve your mental health? Does it matter what strain you take? And how safe is it – can it mess with your memory? To find out, we talk to agricultural scientist Dr. Sean Myles, psychopharmacologist Dr. Amir Englund, and psychologist Dr. Carrie Cuttler. 

Find our transcript here: https://bit.ly/ScienceVsCannabisTranscript 

In this episode, we cover:
(00:00) A New World of Weed
(05:32) Can Different Strains of Weed Do Different Things for You?
(13:18) Can CBD Give You a More Mellow High?
(22:46) Can Weed Help with Anxiety or Depression?
(24:55) What Are The Risks of Using Cannabis?
(35:30) What’s the Safest Way to Use Cannabis?
(38:25) Can Weed Boost Your Creativity?

This episode was produced by Meryl Horn, with help from Wendy Zukerman, Rose Rimler, Michelle Dang, and Joel Werner. We’re edited by Blythe Terrell. Fact checking by Eva Dasher. Mix and sound design by Bobby Lord. Music written by Bobby Lord, Bumi Hidaka and Peter Leonard. Thanks to all the researchers we spoke to including Professor Ryan Vandrey, Professor Christopher Barnes, Dr. Siqi Xue, Professor Susan Tapert, Dr. Michael Dunn, Dr. Linda Parker, Professor Deepak D'Souza, Professor Vikaas Sohal, Professor Loren Frank, and Dr. Ethan Russo. Also thanks to Jill Conforti, the Zukerman Family, Joseph Lavelle Wilson, Bernadette Sciandra, and Chris Suter. 

Science Vs is a Spotify Studios Original. Listen for free on Spotify or wherever you get your podcasts. Follow us and tap the bell for episode notifications. 
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Cannabis: I Get High With a Little Help From … Science

Fasting diets are going bonkers right now — some tech bros are down to one meal a day! And health-fluencers claim that intermittent fasting can help you lose weight, live longer and even fight cancer. But meanwhile, recent headlines are screaming that these diets might actually be dangerous — and linked to death from heart disease. Can science sort this all out?? We speak to nutrition researchers Dr. Krista Varady and Dr. Courtney Peterson, as well as cancer researcher Professor Valter Longo. 

﻿Mental health and disordered eating resources are here: spotify.com/resources 

Find our transcript here: https://bit.ly/ScienceVsFasting

In this episode, we cover:
(00:00) Fasting: the fad and the fears
(03:07) Does fasting help you burn fat?
(07:40) How much weight do people lose with intermittent fasting?
(08:47) Is this just calorie restriction?
(13:17) Can fasting help you live longer?
(19:50) Can fasting fight cancer?

This episode was produced by Kaitlyn Sawrey, Nick DelRose and Wendy Zukerman with help from Michelle Dang, Rose  Rimler, Joel Werner and Meryl Horn. We’re edited by Blythe Terrell, with extra editing help from Caitlin Kenney and Annie-Rose Strasser. Fact checking by Eva Dasher and Michelle Dang. Mix and sound design by Peter Leonard and Bobby Lord. Music by Peter Leonard, Emma Munger, Bumi Hidaka and Bobby Lord. A huge thanks to all the researchers we got in touch with for this episode, including Dr Peter Chisnell, Dr Mikkel Holm Vendelbo, Dr Jiahong Lu, Dr Dorothy Sears, Prof. Mark Mattson, Dr James D Dvorak, Dr Calloway Scott, Professor Richard Billows, Professor Nancy Worman, Dr  Barbara Kowalzig  and the University of Alabama, Birmingham. Also thanks to Kimmie Regler, Helen Zaltman, Frank Lopez, the Zukerman Family, and Joseph Lavelle Wilson. 

Science Vs is a Spotify Studios Original. Listen for free on Spotify or wherever you get your podcasts. Follow us and tap the bell for episode notifications. 
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Intermittent Fasting: Hungry for Facts?

Dreaming might be the weirdest thing that our brains do. Out of thin air we may see ourselves battling a triceratops, or stressing for an exam that we don't have … so why do we do this?? What is going on in our brains to create these bonkers images? For years, the land of dreams was a place for mystics and philosophers, but with groundbreaking technology, we're getting closer to understanding the science of dreams than ever before. Comedians Toni and Ryan join us for a romp through the bizarre science of dreaming, along with neuroscientist Professor Francesca Siclari and dream/sleep researcher Professor Bob Stickgold.

Find our transcript here: https://bit.ly/ScienceVsDreams

In this episode, we cover:
(00:00) Welcome to the Nodcast
(05:11) How our dreams change all night
(08:50) The myth of REM dreams
(14:30) Why do dreams feel so real? 
(22:02) What are we really dreaming about? 
(30:45) Why do we dream? 
(34:46) Could dreams help us process emotions?

This episode was produced by Wendy Zukerman, with help from Joel Werner, Rose Rimler, Meryl Horn, and Michelle Dang. We’re edited by Blythe Terrell. Fact checking by Erica Akiko Howard. Mix and sound design by Bobby Lord. Music written by Bobby Lord, Bumi Hidaka and Peter Leonard. Thanks to all the researchers we spoke to including Dr Dylan Selterman, Dr Nirit Soffer, Professor Caroline Watt, Pr Pilleriin Sikka, Professor Drew Dawson, Dr Başak Türker, Dr Katja Valli, Dr Delphine Oudiette, Dr Sarah Schoch and Dr Dan Rubin. Also thanks to Lauren Silverman, Stupid Old Studios, Andrew Paquette, the Zukerman Family and Joseph Lavelle Wilson.

Science Vs is a Spotify Studios Original. Listen for free on Spotify or wherever you get your podcasts. Follow us and tap the bell for episode notifications. 
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Dreams: What Could They Mean?

We looked at this class of weight loss drugs a year ago, and they've only gotten more popular — and more controversial. We’re hearing that these kinds of drugs can be tough on your stomach, and that the weight loss comes with worrisome loss of muscle. We’ve also heard claims that they might increase your risk of suicide. So — should we be freaking out here?? We talk to endocrinologist Dr. Vibha Singhal, neuroscientist Dr. Nora Volkow, and gastroenterologist Dr. Michael Camilleri.  

This episode does deal with depression and suicidal thoughts. Here are some crisis hotlines: 
United States: US National Suicide Prevention Lifeline Dial 988 (Online chat available); US Crisis Text Line Text “HOME” to 741741
Australia: Lifeline 13 11 14 (Online chat available)
Canada: Canadian Association for Suicide Prevention (See link for phone numbers listed by province)
United Kingdom: Samaritans 116 123 (UK and ROI)
Full list of international hotlines here 

Find our transcript here: https://bit.ly/ScienceVsOzempic2Scarier 

Chapters:
In this episode, we cover:

(00:00) What are the fears around these weight loss drugs? 
(04:46) Do these drugs melt your muscles?
(11:49) Do these drugs increase the risk of suicidal thoughts? 
(16:15) Can they really paralyze your stomach?
(30:25) Some good news!
(33:36) How Did You Find the Bezoar?

CREDITS
This episode was produced by Rose Rimler, with help from Wendy Zukerman, Meryl Horn, Michelle Dang, and Joel Werner. We’re edited by Blythe Terrell. Fact checking by Erica Akiko Howard. Recording assistance from Selena Seay-Reynolds. Mix and sound design by Bobby Lord and Peter Leonard. Music written by Bumi Hidaka, Emma Munger, Peter Leonard, So Wylie and Bobby Lord. Thanks to all of the researchers we spoke to for this episode, including Dr. Kristen Beavers, Dr. Ellen Fallows, Dr. Joseph Henson, Dr. Dimitrios Papamargaritis, Prof. Roger McIntyre, Prof. Russ Waitman, Dr. Sahib Khalsa,, Dr. Travis Masterson, and Dr. Etienne Wang. Thanks also to Bryant Smith and Lori Segal. And special thanks to the listeners on these medications who checked back in with us.   

A special thanks to the Zukerman Family and Joseph Lavelle Wilson.

Science Vs is a Spotify Studios Original. Listen for free on Spotify or wherever you get your podcasts. Follow us and tap the bell for episode notifications. 

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Presenting Not Past It: The Vax That Got Axed

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