Psychopharmacology and Psychiatry Updates

By Psychopharmacology Institute

Science & Medicine Medicine

What's Psychopharmacology and Psychiatry Updates about?

Practical psychopharmacology updates for mental health clinicians. Useful for psychiatry / mental health professionals. Expert interviews and soundbites from lectures. Practical and free of commercial bias. Not sponsored by any pharmaceutical company.

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Postpartum Bipolar Disorder...

11.24.2020

What is the role for lithium in postpartum psychosis? What do we know about mood stabilizers and breastfeeding? Is it possible for women who are using lithium to breastfeed in a safe manner? If your patient is already on a ...

Psychopharmacology and Psychiatry Updates episodes:

11.24.2020 Postpartum Bipolar Disorder and Psychosis: How to Treat? What is the role for lithium in postpartum psychosis? What do we know about mood stabilizers and breastfeeding? Is it possible for women who are using lithium to breastfeed in a safe manner? If your patient is already on a ...
11.19.2020 Lithium: How to Dose and Baseline Testing Specific tests that you need to order before prescribing lithium (baseline testing). How to start lithium. The best way to distribute dosing to prevent kidney damage. The most relevant drug interactions that may affect lithium levels.
11.14.2020 Antipsychotic-Induced Weight Gain: Practical Lessons From A Case Antipsychotic-induced weight gain is a huge problem. Today's episode will remind you of some important concepts from the general medicine perspective. This episode will help you be more systematic about the diagnosis of metabolic syndrome in your clinical practice. It ...
11.09.2020 Akathisia: Tips for Psychiatrists Why is akathisia important? For differential diagnosis, what are the most common conditions that can mimic akathisia? What is pseudoakathisia? What can you do to treat akathisia before adding any new medication? If you need to add a medication, which ...
11.04.2020 Postpartum Psychosis: What Every Clinician Must Know How common is postpartum psychosis? What underlying etiology should we always suspect? How do we differentiate postpartum psychosis from obsessive-compulsive disorder in the postpartum? Is postpartum psychosis an emergency, or can it be handled with outpatient treatment?
10.01.2020 Reducing Suicidal Ideation Through Insomnia Treatment: A Randomized Clinical Trial This episode explores a clinical trial on the use of hypnotics in insomnia associated with suicidal depression.
09.08.2020 The Clinician’s Algorithm To Managing COVID-19 Related Delirium In this podcast, we discuss behavioral and psychopharmacologic management strategies for COVID-19–related delirium.
08.19.2020 Does Samidorphan Reduce Olanzapine-Induced Weight Gain? We discuss a study on the use of the mu-opioid receptor antagonist, samidorphan for olanzapine-induced weight gain, compared to placebo and naltrexone.
07.25.2020 Managing Depression, Anxiety, and Psychosis in Parkinson’s Disease We discuss the prevalence and treatment of depression, psychosis in patients with Parkinson’s Disease.
06.24.2020 Management of Psychiatric Disturbances in Parkinson’s Disease and Other Hypokinetic Movement Disorders We review a study on the management of psychiatric disturbances in Parkinson’s Disease and atypical parkinsonisms.
06.03.2020 Case Discussion: Managing Agitation in Autism Spectrum Disorder A 14-year-old patient with autism spectrum disorder presents to the emergency room with aggressive and agitated behavior. We discuss possible etiologies and psychosocial and pharmacologic management.
05.15.2020 Pharmacotherapy of Autism Spectrum Disorder: Randomized BAART Clinical Trial We review the BAART trial on risperidone vs aripiprazole in irritability associated with autism spectrum disorder.
04.28.2020 Antidepressant Safety During Pregnancy: Autism, IQ and Teratogenicity We discuss studies on the safety of antidepressants in pregnancy regarding autism risk, IQ, cardiac malformations, miscarriage, and neonatal mortality.
03.31.2020 Does Prenatal Stress Predispose to Borderline Personality Disorder? We discuss a study that investigates the relationship between prenatal stress and a diagnosis of borderline personality disorder in offspring.
03.13.2020 Clinical Pearls in Perinatal Psychiatry We explore the case of Rosa, a 36 year old pregnant woman with a history of depression, we discuss how to adjust pharmacotherapy, psychotherapy and other factors to keep in mind.
02.27.2020 What Do You Know About Cognitive Enhancers in Depression? In this podcast episode with Dr. Jim Phelps, we review the evidence for several agents used to help patients with depression and cognitive dysfunction symptoms. We speak about modafinil, vortioxetine, duloxetine and amphetamines.
01.16.2020 Can Lithium Prevent Dementia? In this podcast episode, we delve into the neuroprotective role of lithium in preventing dementia. We review a 2019 randomized controlled trial that administered low-dose lithium to patients with mild cognitive impairment.
12.27.2019 Psychopharm in 2019: Your Ultimate Guide In this podcast episode, we review the major FDA approvals in psychopharmacology for 2019. We explore brexanolone, bremelanotide, the asenapine skin patch, esketamine, cariprazine, and lumateperone.
12.20.2019 Clinical Storytime with Dr. Ken Gillman In this podcast episode, we discuss a case of a 65-year-old patient with first-episode MDD that is treatment resistant. With the expertise of Dr. Ken Gillman, we unpack how to manage this case with an MAOI.
11.27.2019 Do Antidepressants Increase Risk of Dementia? In this podcast episode, we discuss a 2019 study that addresses the question of whether antidepressants increase dementia risk and the possible underlying mechanisms.
11.15.2019 Behind the Scenes: Meet Our Team In this podcast episode, you get to meet some of the humans of Psychopharmacology Institute. We discuss what we enjoy, what we have to offer and how you can join our team.
10.31.2019 “New” Antidepressants? A Quick Takes Episode In this podcast episode, Dr. Jim Phelps shares the findings of a tantalizing study that found that agents like allopurinol, angiotensin agents, aspirin and non-steroidals may be effective for the treatment of depression.
10.17.2019 Why Don’t We Prescribe MAOIs? This episode is the starter pack for the use of monoamine oxidase inhibitors in psychiatry practice. We learn the mechanism of action, food-related instructions and MAOI drug interactions.
10.02.2019 Ketamine for Suicidal Ideation: A Quick Take Episode In this podcast episode, Dr. Jim Phelps reviews a meta-analysis about ketamine for suicidal ideation and how effective it is.
09.19.2019 The Psych Guide to Ketamine and Esketamine In this podcast episode we learn the core concepts surrounding ketamine and esketamine; a very hot topic in psychiatry today. We have Dr. Sam Wilkinson and Dr. Joseph Goldberg joining us.
08.28.2019 Your Psych Guide To Pharmacogenetic Testing In this podcast episode, we dig further into the practical use of pharmacogenetic testing in psychiatric practice. We address its limitations and the resources you can use to guide your decision making.
08.14.2019 Do You Order Pharmacogenetic Testing For Your Patients? In this podcast episode, we question whether pharmacogenetic testing is valuable in psychiatry practice. Joined by Dr. Simon Kung and Dr. Michael Thase, we find answers to this question!
07.31.2019 Podcast: Give Me Some Skin-Transdermal Patches in Psychiatry In this podcast interview with Dr. Leslie Citrome, we venture into the topic of transdermal delivery of psychotropics. We explore the challenge of creating patches and also peek into the latest antipsychotics in clinical trials for transdermal delivery.
07.17.2019 Podcast: Your Guide to Synthetic Opioids and Bath Salts This podcast episode covers the basics of diagnosing and managing novel synthetic opioids and synthetic cathinones.
07.03.2019 Designer Drugs: Can You Handle Spice? The use of designer drugs (novel psychoactive compounds) is rapidly-growing and dangerous, this podcast episode gives you exactly what you need to know to identify and manage these cases.
06.19.2019 What You Need To Know About Psychedelics In this podcast episode, we revisit psychedelics with Dr. David Nutt and Dr. Robin Carhart-Harris. We review how psychedelics work, their potential uses, and adverse effects in managing treatment-resistant depression. We also discuss the use of MDMA in PTSD.
05.31.2019 The Magic of the Serotonin Receptors In this podcast episode, we explore with Dr. David Nutt (Imperial College London) the serotonin receptors 5-HT1A and 5-HT2A and their links to clinical psychiatry. We particularly focus on their roles in mood, anxiety, psychosis, aggression, and learning.
05.16.2019 Generalized Anxiety Disorder: What if You Can’t Use An SSRI? In this podcast episode, we answer the question: What if you can’t use an SSRI for GAD? With expert commentary from Dr. David Osser (Harvard Medical School), we explore different options and also highlight what not to use.
05.03.2019 Approaching A Case of Generalized Anxiety Disorder: The Basics In this podcast episode, we cover the treatment algorithm of generalized anxiety disorder. Dr. David Osser (Harvard Medical School) shares practical tips and anecdotes for your practice.
04.17.2019 How Helpful are Antipsychotic Plasma Levels? In this podcast episode, we investigate the effectiveness of using antipsychotic plasma levels in clinical practice with Dr. Jonathan Meyer (University of California San Diego).
04.08.2019 Should You Prescribe Natural Medications? Part 2 In this podcast episode, we learn about prescribing natural medications in psychiatry with Dr. David Mischoulon (Harvard Medical School). We explore the use of melatonin, Valerian and Ginkgo biloba.
03.21.2019 How to Prescribe Natural Medications? Part 1 In this podcast episode, we learn about prescribing natural medications in psychiatry with Dr. David Mischoulon (Harvard Medical School). We explore St. John’s wort, SAM-e, Omega 3 fatty acids and Rhodiola rosea.
03.08.2019 How to Manage Adverse Effects of Clozapine – Part 2 In this episode, we cover practical tips on the management of fever, cardiovascular and cardiometabolic adverse effects related to clozapine use. Dr. Jonathan Meyer provides evidence-based pearls as well as clinical anecdotes.
02.21.2019 How to Manage Adverse Effects of Clozapine – Part 1 In this episode, we cover practical tips on the management of sialorrhea, constipation, sedation, and seizures related to clozapine use. Dr. Jonathan Meyer provides evidence-based pearls as well as clinical anecdotes.
02.06.2019 Do SSRIs Increase Bleeding Risk? In this episode we answer the question: Do SSRIs increase the risk of bleeding? We do this with Dr. James Levenson (Virginia Commonwealth University) and we explore GIT, perioperative, CNS and postpartum bleeding with SSRIs.
01.25.2019 Your Guide to Treating PTSD Comorbidities In this episode, we explore the management of common PTSD comorbidities with Prof. David Osser (Harvard Medical School). We cover substance use disorder, depression, psychosis and prescribing in women of childbearing potential.
01.09.2019 How to Treat PTSD-Related Sleep Disturbances? In this episode, we discuss part of Dr. David Osser’s (Harvard Medical School) PTSD algorithm about treating sleep symptoms of PTSD. We cover the evidence on prazosin’s efficacy and trazodone use. The rationale behind certain drugs to avoid is also ...
12.28.2018 Prescribing Psychotropics in the Medically Ill In this episode, we review principles of prescribing psychotropics in patients with liver, kidney and lung diseases with Dr. James Levenson (Virginia Commonwealth University).
12.14.2018 Psychotropics and Gastrointestinal Conditions: Prescribe with the Gut in Mind In this episode, we learn to prescribe with the gut in mind. Dr. James Levenson (Virginia Commonwealth University) joins us with to-the-point tips on prescribing psychotropics in patients with GI disease as well as exploring how psychotropics can affect the ...
11.29.2018 Clinical Pearls in Geriatric Psychopharmacology In this episode, we uncover clinical pearls of geriatric psychopharmacology. We are joined by Dr. Sandra Jacobson of the University of Arizona giving practical tips on prescribing for this special group of patients.
11.15.2018 Treatment-Resistant Depression: Clinical Conundrum In this podcast episode, we take on the challenge of treatment-resistant depression and its therapeutic options. Dr. Philip Cowen (University of Oxford) provided insights for this clinical conundrum with a simple algorithm.
10.30.2018 How to Manage an Agitated Patient? In this episode, we venture into the psychopharmacology of agitation, with a special focus on psychotic agitation. Dr. Michael Jibson (University of Michigan) and Dr. David Osser (Harvard Medical School) shared clinical pearls to treat this challenging situation.
10.02.2018 When to Discontinue Antipsychotics? Reviewing the Evidence When is the right time to discontinue an antipsychotic in the treatment of schizophrenia? We reviewed the evidence as well as consulting Dr. Ira Glick to help us answer this question.
08.27.2018 Are Drug Interaction Warnings Influenced by Drug Company Promotion? An Interview with Dr. Jeffery Mattes Dr. Jeffrey Mattes, psychiatrist in Princeton, New Jersey speaks about drug interaction warnings that appear during electronic prescribing and how these warnings may be influenced by drug company promotion. This interview is part of a series covering the 2018 ASCP ...
07.29.2018 Psilocybin for Treatment-Resistant Depression - Dr. Robin Carhart-Harris Dr. Robin Carhart-Harris speaks about the use of psilocybin for treatment-resistant depression. - Psilocybin, a psychedelic, is a 5-HT2A agonist. Stimulation of the 5-HT2A receptor promotes neural plasticity -A potential mechanism of action of psilocybin in treatment-resistant depression involves “brain ...

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