Psychopharmacology and Psychiatry Updates

By Psychopharmacology Institute

Science & Medicine Medicine

What's Psychopharmacology and Psychiatry Updates about?

Practical psychopharmacology updates for mental health clinicians. Useful for psychiatry / mental health professionals. Expert interviews and soundbites from lectures. Practical and free of commercial bias. Not sponsored by any pharmaceutical company.

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LAST EPISODE

How to Treat Hair Pulling a...

04.17.2021

What is the role of N-Acetylcysteine (NAC) for hair-pulling and skin-picking Disorders? Should NAC be used as a first-line treatment?

Psychopharmacology and Psychiatry Updates episodes:

04.17.2021 How to Treat Hair Pulling and Skin-Picking Disorders What is the role of N-Acetylcysteine (NAC) for hair-pulling and skin-picking Disorders? Should NAC be used as a first-line treatment?
04.12.2021 Clozapine and Risk of COVID-19 Infection Can clozapine increase the risk of COVID-19 infection? What is the role of hypersalivation?
04.07.2021 How to Treat Body Dysmorphic Disorder What is the role of SSRIs for body dysmorphic disorder? Should you prescribe antipsychotics? What are the most powerful medications for patients with delusional insight?
04.01.2021 Should Psychotherapy Alone Be First-Line For Depression? What's an optimal treatment of depression according to a network meta-analysis? Should psychotherapy alone be a default first option?
03.27.2021 Body Dysmorphic Disorder: Tips for Diagnosis What are the clinical features of body dysmorphic disorder? How can you body dysmorphic disorder? Tips for screening.
03.19.2021 Oral Contraceptives in Psychiatry: Potential Effects You Should Know Oral contraceptives can have an impact on mood in women with a history of depression. Can they also mimic the effects of chronic psychological stress?
03.14.2021 Hoarding Disorder: Tips for Diagnosis What are the clinical features of hoarding disorder? How can you assess hoarding disorder? Tips for screening. What other comorbidities should you consider?
03.09.2021 Are Long-Acting Injectable Antipsychotics Better Than Orals? Are long-acting injectable antipsychotics better than oral antipsychotics for preventing relapse and re-hospitalization in schizophrenia?
03.04.2021 Antiepileptics in Pregnancy How bad are valproic acid effects in the newborn? Is there a role for carbamazepine and oxcarbazepine? How to prescribe lamotrigine during pregnancy?
02.27.2021 tDCS for Schizophrenia Is transcranial direct current stimulation for negative symptoms of schizophrenia a good idea?
02.22.2021 Antipsychotics in Pregnancy: Are They Safe? How safe are first-generation antipsychotics in pregnancy? What's their teratogenicity risk? How safe are second-generation antipsychotics? Are risks dose-dependent? What glucose test should you order and when?
02.17.2021 Should you prescribe omega-3 fatty acids? Omega-3 fatty acids have been shown in some randomized trials to be more effective than placebo in the treatment of depression, but a Cochrane review concluded that they are no better than placebo. Should you suggest omega-3 fatty acids for ...
02.12.2021 Prescribing Lithium During Pregnancy How does pregnancy affect lithium pharmacokinetics? How do lithium levels fluctuate across the first, second, and third trimesters? How often should you monitor lithium blood levels? Should you stop lithium prior to labor?
02.07.2021 Using E-Cigarettes: What Clinicians Must Know Can e-cigarettes help in smoking cessation? What are the main disadvantages of e-cigarettes? What is a dual user?
02.02.2021 Premenstrual Mood Syndromes: Oral Contraceptives in Psychiatry? Should psychiatrists prescribe oral contraceptives? What is the role of oral contraceptives in the treatment of PMDD? How do oral contraceptives work in premenstrual syndromes?
01.28.2021 Antidepressants for Bipolar Depression What can we conclude from 9 international guidelines addressing the role of antidepressants in the treatment of bipolar depression? Can antidepressants induce treatment resistance? Some authoritative authors say, maybe.
01.23.2021 PMS and PMDD: Intermittent Antidepressant Dosing? Which antidepressant class is effective for the premenstrual syndromes PMS and PMDD? How can you use antidepressants intermittently to relieve PMS symptoms (luteal-phase and symptom-onset dosing)? Should you prescribe only antidepressants that have been approved by the FDA for PMDD?
01.18.2021 Atomoxetine for Adult ADHD Its most common and not-so-common side effects. What other non-stimulants you can use.
01.13.2021 Premenstrual Mood Syndromes: How to Assess? What is the most helpful and accurate way of understanding premenstrual mood symptoms? What is the preferred scale available? Does it have any limitations? Are period tracking apps useful for diagnosing PMDD?
01.08.2021 Adult ADHD: Using Psychostimulans What is preferred: Long-acting or short-acting formulations? What are the general prescribing principles for all psychostimulants? What are their most common side effects? What side effects you should monitor?
01.03.2021 Smoking and Psychotropic Use: Effects on Blood Levels Can smoking affect psychotropic levels? What are the two antipsychotics most commonly affected by smoking? Which is the antidepressant most commonly affected by smoking?
12.29.2020 Lithium: Sexual Side Effects and Cognitive Impairment How should you discuss cognitive complaints with your patients? What does neuropsychological testing tell us about cognitive impairment with lithium? What strategies can you use to mitigate the sexual side effects of lithium?
12.24.2020 Top 10 Drug Combinations in Major Depressive Disorder: Interview with Dr. Michael Thase PART 2 This interview discusses the use of lithium, thyroid hormone, second-generation antipsychotics, newer antidepressants, and ketamine/esketamine as adjunctive agents in managing major depressive disorder.
12.19.2020 Top 10 Drug Combinations in Major Depressive Disorder: Interview with Dr. Michael Thase PART 1 This interview discusses the use of MAOIs and tricyclic antidepressant combinations, adjunctive benzodiazepines and trazodone, and the use of psychostimulants as adjunctive agents in managing major depressive disorder.
12.14.2020 Managing Tardive Dyskinesia: Clinical Pointers What is the best way to approach tardive dyskinesia? This episode will discuss an algorithm with levels of evidence for each treatment option. What is the evidence level for second-generation VMAT-2 inhibitors, such as deutetrabenazine and valbenazine? Is there evidence ...
12.09.2020 Lithium: How to Manage Weight Gain and GI Side Effects What are the causes of weight gain from lithium? How should you help patients manage their weight gain? What are the most common gastrointestinal side effects? How should you manage patients’ gastrointestinal side effects?
12.04.2020 Liver Function Tests in Psychiatry: Practical Interpretation Tips This episode will offer practical guidance and answer questions about how to interpret abnormal liver function tests in a patient taking psychotropic medications.
11.29.2020 Managing Extrapyramidal Symptoms: Clinical Pointers Are there any biomarkers or neuroimaging studies that help us differentiate drug-induced EPS from Parkinson’s disease? What can you do after you identify extrapyramidal symptoms? What should be your first step? Is it okay to use anticholinergic agents prophylactically? What ...
11.24.2020 Postpartum Bipolar Disorder and Psychosis: How to Treat? What is the role for lithium in postpartum psychosis? What do we know about mood stabilizers and breastfeeding? Is it possible for women who are using lithium to breastfeed in a safe manner? If your patient is already on a ...
11.19.2020 Lithium: How to Dose and Baseline Testing Specific tests that you need to order before prescribing lithium (baseline testing). How to start lithium. The best way to distribute dosing to prevent kidney damage. The most relevant drug interactions that may affect lithium levels.
11.14.2020 Antipsychotic-Induced Weight Gain: Practical Lessons From A Case Antipsychotic-induced weight gain is a huge problem. Today's episode will remind you of some important concepts from the general medicine perspective. This episode will help you be more systematic about the diagnosis of metabolic syndrome in your clinical practice. It ...
11.09.2020 Akathisia: Tips for Psychiatrists Why is akathisia important? For differential diagnosis, what are the most common conditions that can mimic akathisia? What is pseudoakathisia? What can you do to treat akathisia before adding any new medication? If you need to add a medication, which ...
11.04.2020 Postpartum Psychosis: What Every Clinician Must Know How common is postpartum psychosis? What underlying etiology should we always suspect? How do we differentiate postpartum psychosis from obsessive-compulsive disorder in the postpartum? Is postpartum psychosis an emergency, or can it be handled with outpatient treatment?
10.01.2020 Reducing Suicidal Ideation Through Insomnia Treatment: A Randomized Clinical Trial This episode explores a clinical trial on the use of hypnotics in insomnia associated with suicidal depression.
09.08.2020 The Clinician’s Algorithm To Managing COVID-19 Related Delirium In this podcast, we discuss behavioral and psychopharmacologic management strategies for COVID-19–related delirium.
08.19.2020 Does Samidorphan Reduce Olanzapine-Induced Weight Gain? We discuss a study on the use of the mu-opioid receptor antagonist, samidorphan for olanzapine-induced weight gain, compared to placebo and naltrexone.
07.25.2020 Managing Depression, Anxiety, and Psychosis in Parkinson’s Disease We discuss the prevalence and treatment of depression, psychosis in patients with Parkinson’s Disease.
06.24.2020 Management of Psychiatric Disturbances in Parkinson’s Disease and Other Hypokinetic Movement Disorders We review a study on the management of psychiatric disturbances in Parkinson’s Disease and atypical parkinsonisms.
06.03.2020 Case Discussion: Managing Agitation in Autism Spectrum Disorder A 14-year-old patient with autism spectrum disorder presents to the emergency room with aggressive and agitated behavior. We discuss possible etiologies and psychosocial and pharmacologic management.
05.15.2020 Pharmacotherapy of Autism Spectrum Disorder: Randomized BAART Clinical Trial We review the BAART trial on risperidone vs aripiprazole in irritability associated with autism spectrum disorder.
04.28.2020 Antidepressant Safety During Pregnancy: Autism, IQ and Teratogenicity We discuss studies on the safety of antidepressants in pregnancy regarding autism risk, IQ, cardiac malformations, miscarriage, and neonatal mortality.
03.31.2020 Does Prenatal Stress Predispose to Borderline Personality Disorder? We discuss a study that investigates the relationship between prenatal stress and a diagnosis of borderline personality disorder in offspring.
03.13.2020 Clinical Pearls in Perinatal Psychiatry We explore the case of Rosa, a 36 year old pregnant woman with a history of depression, we discuss how to adjust pharmacotherapy, psychotherapy and other factors to keep in mind.
02.27.2020 What Do You Know About Cognitive Enhancers in Depression? In this podcast episode with Dr. Jim Phelps, we review the evidence for several agents used to help patients with depression and cognitive dysfunction symptoms. We speak about modafinil, vortioxetine, duloxetine and amphetamines.
01.16.2020 Can Lithium Prevent Dementia? In this podcast episode, we delve into the neuroprotective role of lithium in preventing dementia. We review a 2019 randomized controlled trial that administered low-dose lithium to patients with mild cognitive impairment.
12.27.2019 Psychopharm in 2019: Your Ultimate Guide In this podcast episode, we review the major FDA approvals in psychopharmacology for 2019. We explore brexanolone, bremelanotide, the asenapine skin patch, esketamine, cariprazine, and lumateperone.
12.20.2019 Clinical Storytime with Dr. Ken Gillman In this podcast episode, we discuss a case of a 65-year-old patient with first-episode MDD that is treatment resistant. With the expertise of Dr. Ken Gillman, we unpack how to manage this case with an MAOI.
11.27.2019 Do Antidepressants Increase Risk of Dementia? In this podcast episode, we discuss a 2019 study that addresses the question of whether antidepressants increase dementia risk and the possible underlying mechanisms.
11.15.2019 Behind the Scenes: Meet Our Team In this podcast episode, you get to meet some of the humans of Psychopharmacology Institute. We discuss what we enjoy, what we have to offer and how you can join our team.
10.31.2019 “New” Antidepressants? A Quick Takes Episode In this podcast episode, Dr. Jim Phelps shares the findings of a tantalizing study that found that agents like allopurinol, angiotensin agents, aspirin and non-steroidals may be effective for the treatment of depression.

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