Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Real Life Pharmacology - Pharmacology Education for Health Care Professionals episodes:

• 04.18.2024

  Top 10 Anticoagulant Drug Interactions

  Today’s sponsor of the Top 10 Anticoagulant Drug Interactions podcast is FreedAI. Freed listens, transcribes, and writes medical documentation for you. FreedAI is offering a discount exclusive to RLP listeners! Users will get $50 off their first month with Freed! Use the discount...

  
• 04.11.2024

  Top 10 SSRI Drug Interactions Podcast

  Today's sponsor of the Top 10 SSRI Drug Interactions podcast is FreedAI. Freed listens, transcribes, and writes medical documentation for you. FreedAI is offering a discount exclusive to RLP listeners! Users will get $50 off their first month with Freed! Use...

  
• 04.04.2024

  Travoprost Pharmacology

  On this episode, I discuss travoprost pharmacology, adverse effects, administration, and much more on this podcast episode. Travoprost is used to reduce intraocular pressure in the management of glaucoma. I discuss the mechanism of action and adverse effects. Travoprost is...

  
• 03.28.2024

  Beers Criteria Podcast Part 2 or 2

  On this podcast episode, I finish up my breakdown of the Beers Criteria. I cover the use of sliding-scale insulin and sulfonylureas in geriatric patients. Hypoglycemia is a major concern with both of these diabetes management strategies. PPIs show up...

  
• 03.21.2024

  Beers Criteria Podcast Part 1 or 2

  In this podcast episode, I break down some of the most common medications that show up on the Beers criteria list. I discuss cardiovascular medications in this podcast episode, including rivaroxaban and warfarin, and why they show up on the...

  
• 03.14.2024

  Navigating QTc Prolongation and Drug Interactions

  On this episode, I discuss the pharmacology surrounding QTc prolongation and drug interactions. I discuss which medications are more likely to cause QTc prolongation and which patient populations we should be more concerned about. Antiarrhythmics are a common class of...

  
• 03.07.2024

  Risedronate Pharmacology Podcast

  On this podcast episode, I cover risedronate pharmacology, adverse effects, drug interactions, and much more. There is a strict administration procedure with risedronate which is designed to reduce adverse effects and enhance absorption. I discuss this in the podcast. Many...

  
• 02.29.2024

  Antihypertensive Drug Interactions Podcast – Episode 316

  On this podcast episode, I discuss some of the most common antihypertensive drug interactions you need to know. One major interaction I discuss is the trifecta of a diuretic, an ACE or ARB, and an NSAID. This combination significantly increases...

  
• 02.22.2024

  Teplizumab For Diabetes Episode 315 – Real Life Pharmacology Podcast

  Teplizumab is a relatively new agent that helps delay the progression of type 1 diabetes. It slows the rate of beta-cell destruction in the pancreas. Teplizumab is associated with cytokine release syndrome which can result in flu-like symptoms of fever,...

  
• 02.15.2024

  Captopril Pharmacology Podcast – Episode 314

  On this podcast episode, I discuss captopril pharmacology, kinetics, interactions, and much more! Captopril is an ACE Inhibitor. It can cause hyperkalemia, cough, and renal impairment. One of the notable issues with captopril is its relatively short half-life which requires it...

  
• 02.08.2024

  Mechanisms of Drug Interactions Episode 313

  On this episode of the Real Life Pharmacology podcast, I take a dive into the most common mechanisms of drug interactions. Below I list some of the common drug interactions seen in practice and how they work! Opposing Effects Many drugs will...

  
• 02.01.2024

  Insulin Aspart (Novolog) Pharmacology Podcast Episode 312

  On this podcast episode, I discuss insulin aspart pharmacology, adverse effects, drug interactions, and much more. Insulin apart is a rapid acting insulin product meant to bring down blood sugars quickly (most often after meals). It is important to remember...

  
• 01.25.2024

  Gentamicin Pharmacology Podcast Episode 311

  On this podcast episode, I discuss gentamicin pharmacology, adverse effects, monitoring, drug interactions and much more! Drug monitoring is critical with gentamicin. Trough and peak concentrations can guide therapy and identify someone at risk of toxicity. Nephrotoxicity is a major concern...

  
• 01.18.2024

  Fenofibrate Pharmacology Podcast Episode 310

  On this podcast episode, I discuss fenofibrate pharmacology, adverse effects, kinetics, drug interactions, and much more! Fenofibrate is typically only used for hypertriglyceridemia. The primary risk of hypertriglyceridemia is pancreatitis so we treat these levels because of this risk. LFTs elevation...

  
• 01.11.2024

  Levofloxacin Pharmacology Podcast Episode 309

  On this podcast episode, I discuss levofloxacin pharmacology, adverse effects, boxed warnings, interactions, and much more. Levofloxacin is well known to cause QTc prolongation and many drugs can increase this risk such as antiarrhythmics, citalopram, antipsychotics, and many more. Binding...

  
• 01.04.2024

  Darifenacin Pharmacology Podcast – Episode 308

  On this podcast episode, I discuss darifenacin pharmacology, adverse effects, drug interactions and much more. CYP3A4 and CYP2D6 are important enzymes in relation to darifenacin. I breakdown the importance of these enzymes and how they can impact drug therapy. Darifenacin...

  
• 12.28.2023

  Naltrexone Pharmacology Podcast – Episode 307

  In this podcast episode, I discuss naltrexone pharmacology, adverse effects, drug interactions, and much more. Naltrexone is an opioid antagonist and can blunt the effects of opioid agonists. Because of this, the medication can be used to manage opioid use...

  
• 12.21.2023

  Acamprosate Pharmacology Podcast – Episode 306

  On this podcast episode, I discuss acamprosate pharmacology, adverse effects, drug interactions, and much more! Acamprosate's most common adverse effect is diarrhea. It is a primary reason why patients will ask to stop taking this medication. It is critical to assess...

  
• 12.14.2023

  Alfuzosin Pharmacology Podcast

  On this podcast episode, I discuss alfuzosin pharmacology, adverse effects, drug interactions, and much more! Alfuzosin is an alpha blocker used to help relieve the symptoms of BPH. Low blood pressure is a possible adverse effect of alfuzosin and is more...

  
• 12.07.2023

  Methadone Pharmacology Podcast

  In this podcast episode, I discuss methadone pharmacology, adverse effects, drug interactions, and pharmacokinetics. Methadone is a full opioid agonist that may be used for pain management and opioid use disorder. Transitioning from methadone to another opioid is complicated. I...

  
• 11.30.2023

  Meperidine Pharmacology Podcast

  On this podcast episode, I discuss meperidine pharmacology, adverse effects, pharmacokinetics, drug interactions, and much more! Meperidine is an opioid that is seldom used due to neurotoxicity. I describe how this can happen in this podcast episode. Meperidine has numerous drug interactions...

  
• 11.23.2023

  Guanfacine Pharmacology Podcast

  On this episode of the podcast, I cover guanfacine pharmacology, adverse effects, drug interactions, and much more. Guanfacine is a central acting alpha-2 agonist that has the brand names of Tenex and Intuniv. Because of guanfacine's mechanism of action, it...

  
• 11.16.2023

  Fluvastatin Pharmacolgy Podcast

  On this podcast episode, I discuss fluvastatin pharmacology, adverse effects, pharmacokinetics, and much more. Fluvastatin is only a low to moderate-intensity statin which explains its limited use compared to rosuvastatin or atorvastatin. I discuss drug interactions in the podcast but...

  
• 11.09.2023

  Oxymorphone Pharmacology Podcast

  In this episode, I discuss oxymorphone pharmacology, adverse effects, drug interactions, and more! Oxymorphone is approximately 3 times more potent than morphine. I break down some common opioid comparisons in this episode. Oxymorphone avoids many of the CYP interactions. I discuss...

  
• 11.02.2023

  Diclofenac Pharmacology Podcast

  On this podcast episode, I discuss diclofenac pharmacology, adverse effects, drug interactions, and much more. Diclofenac is one of the highest-risk NSAIDs when it comes to cardiovascular risk. You can find more information on this in the Meded101 NSAID comparison...

  
• 10.26.2023

  Aliskiren Pharmacology Podcast

  On this episode, I discuss aliskiren pharmacology, adverse effects, drug interactions, and much more. Aliskiren should not be used with ACE Inhibitors or ARBs. I discuss why that is in this episode. Aliskiren has a long enough half-life at approximately...

  
• 10.19.2023

  Buprenorphine/Naloxone Pharmacology Podcast

  On this episode, I discuss the use of buprenorphine/naloxone in managing opioid use disorder. I cover the kinetics, dosage forms, adverse effect, interactions and much more. Buprenorphine/naloxone has numerous dosage form and they are not interchangeable. I discuss this further...

  
• 10.12.2023

  Spironolactone Pharmacology Podcast

  On this episode, I discuss spironolactone pharmacology, adverse effects, drug interactions and much more. Spironolactone has numerous indications including hypertension, CHF, ascites, and acne. I break them all down in this podcast episode. Hyperkalemia is a major concern with spironolactone. Patients...

  
• 10.05.2023

  Meloxicam Pharmacology Podcast

  I discuss meloxicam pharmacology, adverse effects, drug interactions, and much more on this episode of the Real Life Pharmacology Podcast. Meloxicam tends to have a greater affinity to COX-2 versus COX-1. I discuss what this means clinically on this episode....

  
• 09.28.2023

  Enalapril Pharmacology Podcast

  On this episode, I discuss enalapril pharmacology, adverse effects, drug interactions, and much more! Enalapril has a shorter half-life compared to some of the other ACE inhibitors so it may need to be dosed twice daily in patients with adequate renal...

  
• 09.21.2023

  Asthma Pharmacotherapy Q&A With Beth Zerr, PharmD, BCACP

  On this very special episode of the Real Life Pharmacology podcast, we tackle asthma pharmacotherapy and some of the things that Beth sees in her everyday practice as an ambulatory care pharmacist. When discussing asthma pharmacotherapy with pediatric patients and...

  
• 09.14.2023

  Lisdexamfetamine Pharmacology Podcast

  On this podcast episode, I discuss lisdexamfetamine (Vyvanse) pharmacology, adverse effects, drug interactions, and much more. Lisdexamfetamine is a stimulant medication that is used in the management of ADHD. Stimulants like lisdexamfetamine can increase heart rate, raise blood pressure, and...

  
• 09.07.2023

  Etanercept Pharmacology Podcast

  On this podcast episode, I cover etanercept pharmacology, adverse effects, drug interactions and much more. Etanercept is classified as a DMARD but is different from older DMARDs in that it is a biologic agent and needs to be injected. Vaccination...

  
• 08.31.2023

  Insulin Lispro (Humalog) Pharmacology Podcast

  On this podcast episode, I discuss the pharmacology, adverse effects, and drug interactions of insulin lispro (Humalog). I spend some time on this podcast episode discussing carb ratios and sliding scale insulin when using insulin lispro. Potassium is critical to monitor...

  
• 08.24.2023

  Pregabalin Pharmacology Podcast

  On this podcast episode, I discuss (Lyrica) pregabalin pharmacology, adverse effects, drug interactions, and much more. I compare pregabalin and gabapentin in this episode and one important difference is the percent absorption of gabapentin compared to pregabalin. Pregabalin can exacerbate...

  
• 08.17.2023

  Tamoxifen Pharmacology Podcast

  On this podcast episode, I discuss tamoxifen pharmacology, adverse effects, drug interaction, and much more. Tamoxifen is converted to a more active compound in the body by CYP2D6. CYP2D6 inhibitors such as paroxetine, fluoxetine, or bupropion can essentially reduce the effectiveness...

  
• 08.10.2023

  Phenobarbital Pharmacology Podcast

  On this episode of the Real Life Pharmacology Podcast, I cover phenobarbital pharmacology, adverse effects, important drug interactions and much more. Phenobarbital is an enzyme inducer. It is an inducer at CYP3A4 so this can lead to numerous drug interactions. Phenobarbital...

  
• 08.03.2023

  Isotretinoin Pharmacology Podcast

  On this episode, I discuss isotretinoin pharmacology, side effects, drug interactions, and much more. The iPLEDGE program is in place to ensure that pregnant patients do not receive this medication. I discuss this in more detail on this episode. Sun...

  
• 07.27.2023

  Lovastatin Pharmacology Podcast

  On this episode of the Real Life Pharmacology Podcast, I discuss lovastatin pharmacology, adverse effect, drug interactions, and more! Lovastatin is broken down by CYP3A4 so drugs like clarithromycin, diltiazem, and others may increase concentrations. Lovastatin is a lipophilic statin and...

  
• 07.20.2023

  Clindamycin Pharmacology Podcast

  On this podcast episode, I discuss clindamycin pharmacology, adverse effects, drug interactions, and much more! Clindamycin (oral administration) can cause esophageal irritation and it is recommended to take this medication with a full glass of water. C. Diff risk and frequent...

  
• 07.13.2023

  Dextroamphetamine Pharmacology Podcast

  On this podcast episode, I discuss dextroamphetamine's pharmacology, adverse effects, drug interactions, and much more! Dextroamphetamine is a stimulant medication. Weight loss, insomnia, tachycardia, and hypertension are all possible complications. There is a patch dosage form of dextroamphetamine available called Xelstrym....

  
• 07.06.2023

  Vardenafil Pharmacology Podcast

  On this podcast episode, I discuss vardenafil pharmacology, adverse effects, drug interactions, and much more. Vardenafil is a PDE-5 inhibitor used primarily for erectile dysfunction in males. Using nitrates with vardenafil is contraindicated due to the risk of profound hypotension....

  
• 06.29.2023

  Niacin Pharmacology Podcast

  On this podcast episode, I discuss niacin pharmacology, adverse effects, drug interactions, and much more. Niacin has historically been used to manage lipids but has fallen out of favor due to adverse effects, and newer, more effective therapies being developed. Niacin...

  
• 06.22.2023

  Dextromethorphan Pharmacology Podcast

  I discuss dextromethorphan pharmacology, adverse effects, drug interactions, and more on this podcast episode. CYP2D6 metabolizes Dextromethorphan. A commonly used antidepressant is a CYP2D6 inhibitor. I discuss this on the podcast. Dextromethorphan is a commonly used OTC cough suppressant. There...

  
• 06.15.2023

  Bexagliflozin Pharmacology Podcast

  On this podcast episode, I discuss bexagliflozin pharmacology, adverse effects, drug interactions, and much more. I wasn't wowed by the A1C reduction of this medication. I get into the specifics on bexagliflozin in the podcast episode. SGLT2 inhibitors like bexagliflozin...

  
• 06.08.2023

  Cefuroxime Pharmacology Podcast

  On this episode, I discuss cefuroxime pharmacology, adverse effects, drug interaction, pharmacokinetics, and much more. Cefuroxime is a 2nd generation cephalosporin that binds Penicillin-binding proteins and prevents bacterial cell wall synthesis. Medications that create a higher pH in the stomach...

  
• 06.01.2023

  Risperidone Pharmacology Podcast

  On this episode, I discuss risperidone pharmacology, adverse effects, monitoring, and common indications. There are numerous drug interactions that I discuss in this podcast episode. CYP2D6 inhibitors may increase drug concentrations. Risperidone increases prolactin more than most 2nd generation antipsychotics....

  
• 05.25.2023

  Vortioxetine Pharmacology Podcast

  On this podcast episode, I discuss vortioxetine pharmacology, adverse effects, drug interactions, and much more. Because of vortioxetine's long half-life, antidepressant discontinuation syndrome is going to be less prominent compared to ADPs with shorter half-lives. Vortioxetine is metabolized by CYP2D6. Drugs...

  
• 05.18.2023

  Isosorbide Mononitrate Pharmacology Podcast

  On this episode, I discuss isosorbide mononitrate pharmacology, adverse effects, and important drug interactions. Isosorbide mononitrate is a vasodilator that works by relaxing and widening the blood vessels (primarily veins) through nitric oxide action. This reduces the preload and oxygen...

  
• 05.11.2023

  Azelastine Nasal Spray Pharmacology Podcast

  On this episode of the RLP podcast, I discuss azelastine nasal spray pharmacology, adverse effects, administration, and much more! While most nasal sprays for allergic rhinitis are corticosteroids, azelastine is classified as an antihistamine. Systemic absorption of azelastine is about 40%, so...