Dr. Denver Lough is President, Chief Executive Officer, and Chairman of PolarityTE, a biotech company developing methods for patients’ own cells to regenerate functionally-polarized tissues. Denver and the team at Polarity TE have developed novel methods to successfully induce regeneration across the full spectrum of tissue types including skin, muscle, and bone. They have accomplished this by understanding the environment, stimuli, and interactions needed for these tissues to orient, self-organize, and develop. With their technology, patients with a variety of diseases and injuries can regenerate fully functional tissues from their own cells. When he isn’t working at PolarityTE, Denver enjoys spending time with his wife and three young children. It is exciting to watch them learn and discover new things about the world, and it makes Denver appreciate all the incredible things in life that we sometimes overlook. Denver received his MD and PhD in Biochemistry and Molecular and Cell Biology from Georgetown University. He completed his residency in Plastic Surgery at Johns Hopkins University. Afterwards, Denver founded PolarityTE. In our interview Denver will tell us more about his life and science.

498: Researching Novel Methods to Regenerate Functionally-Polarized Tissues - Dr. Denver Lough

Are you searching for great stories to ignite your curiosity, teach you to perform better in life and career, inspire your mind, and make you laugh along the way? In this science podcast, Dr. Marie McNeely introduces you to the brilliant researchers behind the latest scientific discoveries. Join us as they share their greatest failures, most staggering successes, candid career advice, and what drives them forward in life and science.

<![CDATA[<a href="http://www.peoplebehindthescience.com/podcasts">Our website with show notes]]

Greetings science fans!

We’re elated to welcome you to People Behind the Science where we explore the lives and experiences of the people behind the research and scientific discoveries of today.

People Behind the Science’s mission is to inspire current and future scientists, share the different paths to a successful career in science, educate the general population on what scientists do,  and show the human side of science.

In each episode, a different scientist will guide us through their journey by sharing their successes, failures, and passions. We are excited to introduce you to these inspiring academic and industry experts from all fields of science to give you a variety of perspectives on the life and path of a scientist.

Our esteemed guests will tell you:

    what motivates them and how they balance their competing responsibilities
    how they worked through some of the most challenging times in their careers
    advice to help you through your own journey through life and science

 
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People Behind the Science is a podcast focused on the people doing fascinating research through interviews with top scientists. We are proud to have interviewed so many inspiring scientists, including U.S. National Academy scientists like Josh Sanes, Nick Spitzer, Lou Muglia, Jacob Israelachvili, Gene Robinson, Larry Squire, John Dowling, James Berger, and David Spergel, as well as popular scientists in the media like Donna Nelson (science advisor for the TV show Breaking Bad) and Jack Horner (science advisor for the Jurassic park movies). We are honored to have shared their amazing stories with people in all 50 states in the USA and in over 120 countries across the world.

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Dr. Lin Tian is a Scientific Director at the Max Planck Florida Institute for Neuroscience and Clinical Professor at the University of California, Davis. The main goal of Lin’s lab is to develop, leverage, and also share novel optical and molecular tools that can help us to characterize neural signaling and find new treatment targets for neuropsychiatric disorders. In addition to her scientific and leadership roles, Lin is a mom, wife, and daughter. She often spends her free time with her family, driving her two sons to different activities, cheering for them at their swim meets and baseball games, and helping them with homework. Lin also enjoys walking her dog and doing things around the house. She earned her B.S. in Neuroscience from the University of Science and Technology of China and her Ph.D. in Biochemistry, Molecular, and Cellular Biology from Northwestern University. She then completed postdoctoral training at Howard Hughes Medical Institute’s Janelia Research Campus. Lin remained at HHMI as a Research Specialist before joining the faculty at the University of California, Davis School of Medicine in 2012. She began her current position at Max Planck in 2023. Lin has received multiple awards and honors, including an NIH New Innovator Award, the W.M. Keck Foundation Award, the Human Frontier Science Program Young Investigator Award, and she has been named a Rita Allen Scholar and Hartwell Scholar. In our interview, she shares more about her life and science.

757: Developing Molecular Biotechnology Tools for Neural Dynamics Research and Novel Therapeutics - Dr. Lin Tian

Dr. Maureen Murphy is a Professor and Program Leader in the Molecular and Cellular Oncogenesis Program of the Wistar Institute Cancer Center in Philadelphia. She is also the Associate Vice president for Faculty Affairs and Associate Director For Education and Career Development there. Maureen’s research is aimed at understanding and developing cures for cancer. Specifically, they focus on the p53 tumor suppressor protein that is responsible for stopping tumors from forming. When she’s not in the lab, you can find Maureen hiking outside with her dogs. She loves nature and thinks dogs are wonderful for reminding us to take a break from our hectic schedules to enjoy life. Maureen is also a fan of traveling, cycling, and yoga. Maureen received her B.S. in biochemistry from Rutgers University and a Ph.D. in molecular biology from the University of Pennsylvania School of Medicine. After graduate school, she completed postdoctoral research at Princeton University. Maureen served on the faculty at the Fox Chase Cancer Center before accepting her current position at the Wistar Institute. Maureen is with us today to tell us all about her journey through life and science.

756: Passionately Pursuing Projects on the P53 Tumor Suppressor Protein - Dr. Maureen Murphy

Dr. Carlos Portela is the Brit and Alex d'Arbeloff Career Development Professor in Mechanical Engineering at MIT. Carlos’s research involves designing, making, and testing new types of materials that have unconventional properties. To do this, they rearrange the components of existing materials in three dimensions at the micro or nano scale to create new architected materials. The new materials may absorb a lot of energy upon impact, or be extremely lightweight, but also very stiff. When he’s not working, Carlos likes to stay active by running, playing golf, and playing a variety of team sports. He also enjoys exploring new restaurants in Boston, particularly places that serve Asian-Spanish fusion food. He received his bachelor's degrees in aerospace engineering and physics from the University of Southern California, his M.S. and Ph.D. degrees in mechanical engineering from the California Institute of Technology (Caltech). Carlos remained at Caltech to conduct postdoctoral research before joining the faculty at MIT. He was the recipient of an NSF Faculty Early Career Development (CAREER) Award, and he has also been named among MIT Tech Review’s 35 Innovators Under 35. In this interview, he shares more about his life and research.

755: Designing, Creating, and Testing Novel Materials with Unique Properties - Dr. Carlos Portela

Dr. Joel Fodrie is an Assistant Professor in the Institute of Marine Sciences and Department of Marine Sciences at the University of North Carolina at Chapel Hill. Joel studies estuaries which are habitats where freshwater from rivers and streams mixes with the salt water of the ocean. He acts as a sort of detective to investigate how things like salt marshes, sea grasses, and oyster reefs keep this habitat healthy and to determine what may be driving observed changes in fish abundance in these areas. Joel has always loved going out on the water for activities like fishing, surfing, and boating. He got his first boat when he was only 13 years old! In addition, Joel is also an enthusiastic basketball player and reader of Revolutionary Era history books and biographies. He received his undergraduate training in Biology and History from the University of North Carolina at Chapel Hill and went on to receive his Ph.D. in Biological Oceanography from the Scripps Institution of Oceanography at the University of California, San Diego. Afterward, Joel conducted postdoctoral research with the Marine Sciences Consortium at the Dauphin Island Sea Lab. Joel served on the faculty at the University of South Alabama before joining the faculty at the University of North Carolina at Chapel Hill where he is today. Joel is here with us today to tell us all about his journey through life and science.

754: Hooked on Researching Marine Coastal Ecosystems and Fish Abundance - Dr. Joel Fodrie

Dr. Taylor Hutchison is an astrophysicist and a Postdoctoral Fellow at the NASA Goddard Space Flight Center. Taylor uses large telescopes like the James Webb Space Telescope to study the most distant galaxies that we can detect in the universe. Her goal is to answer questions like what kinds of stars are inside these galaxies, how massive the galaxies are, and what elements are present. When she’s not working, Taylor engages in a variety of hobbies, crafts, and opportunities to learn new skills. She particularly enjoys reading, hiking, sewing her own clothing, and creatively reusing items that may have otherwise been thrown away. For example, she uses recycled cardboard and newspapers to make baskets and other tools. She received her bachelor’s degree in physics from Southwestern University and her Master’s and PhD degrees in Astronomy from Texas A&M; University. She was the recipient of the Dr. Joseph Newton Graduate Service Award, a University Prestigious Fellowship Scholarship, the Leadership in Equity and Diversity (LEAD) Award, and the Graduate Diversity Excellence Award from Texas A&M; University, and she also received a National Science Foundation Graduate Research Fellowship as well. In this interview, Taylor shares more about her life and science.

498: Researching Novel Methods to Regenerate Functionally-Polarized Tissues - Dr. Denver Lough

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