We discuss transformative role of Artificial Intelligence (AI) and Machine Learning (ML) in predicting and responding to pandemics. We highlight how AI systems, like BlueDot, offer crucial early warnings by analyzing vast and diverse datasets, ultimately saving lives. We explain the underlying AI techniques, such as predictive analytics, deep learning, and natural language processing, that enable this foresight. Finally, we address the ethical considerations and challenges associated with AI's deployment in public health, emphasizing the need for responsible and equitable use.