A discussion with Drs. Nancy Everds, Nianyu Li and Katherine Sprugel from Amgen in Seattle, Washington about the article “Unexpected thrombocytopenia and anemia in cynomolgus monkeys induced by a therapeutic human monoclonal antibody”.  This manuscript won the journal’s best paper award in 2013 and describes a study that is a cautionary tale for those investigating/testing monoclonal antibodies.
 
Click here to read the full article.  

TPX: Unexpected Thrombocytopenia and Anemia in Cynomolgus Monkeys Induced by a Therapeutic Human Monoclonal Antibody

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Podcast Editor, Liz McInnes, interviews author Armelle Grevot regarding their article, "Toxicologic Pathology Forum Opinion Piece: Use of Virtual Control Groups in Nonclinical Toxicity Studies: The Anatomic Pathology Perspective" which can currently be found in Volume 51, Issue 6 of Toxicologic Pathology. Click here to read the article

TPX 2023 Series - EP6: Toxicologic Pathology Forum Opinion Piece: Use of Virtual Control Groups in Nonclinical Toxicity Studies: The Anatomic Pathology Perspective

Podcast Editor, Tracy Carlson, interviews authors Sundeep Chandra and Brian Long regarding their article, "Safety Findings of Dosing Gene Therapy Vectors in NHP With Pre-existing or Treatment-Emergent Anti-capsid Antibodies" which can currently be found in Volume 51, Issue 5 of Toxicologic Pathology. Click here to read the article

TPX 2023 Series - EP5: Safety Findings of Dosing Gene Therapy Vectors in NHP With Pre-existing or Treatment-Emergent Anti-capsid Antibodies

In this new episode of Veterinary Dentistry Matters, John Lewis, former Editor-in-Chief of the Journal of Veterinary Dentistry, interviews Bonnie Shope. The official podcast of the Journal of Veterinary Dentistry, “Veterinary Dentistry Matters,” provides interviews with those who influenced the specialty during its inception and with those who continue to affect its trajectory. In addition to interviews with our specialist colleagues, the podcast will be an opportunity to discuss specific authors’ manuscripts in further detail and popular topics as they arise.

JOVD: Veterinary Dentistry Matters with Bonnie Shope

 Podcast Editor, Liz McInnes, interviews author Diethilde Theil regarding the article, "Neurofilament Light Chain: A Translational Safety Biomarker for Drug-Induced Peripheral Neurotoxicity" which can currently be found in Volume 51, Issue 3 of Toxicologic Pathology.     Click here to read the article

TPX 2023 Series - EP4: Neurofilament Light Chain: A Translational Safety Biomarker for Drug-Induced Peripheral Neurotoxicity

 Podcast Editor, Erin Quist, interviews authors Brad Bolon, Ingrid Pardo, and LaTasha Crowford regarding the article, "Scientific and Regulatory Policy Committee Points to Consider: Sampling, Processing, Evaluation, Interpretation, and Reporting of Test Article-Related Ganglion Pathology for Nonclinical Toxicity Studies" which can currently be found in Volume 51, Issue 4 of Toxicologic Pathology.     Click here to read the article

TPX 2023 Series - EP3: Scientific and Regulatory Policy Committee Points to Consider: Sampling, Processing, Evaluation, Interpretation, and Reporting of Test Article-Related Ganglion Pathology for Non

TPX: Unexpected Thrombocytopenia and Anemia in Cynomolgus Monkeys Induced by a Therapeutic Human Monoclonal Antibody

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