Dr. Chapa’s OBGYN Clinical Pearls

Treat Non-Severe PreE with BP Meds?


Listen Later

Welcome back, everyone. Today we're diving into one of the most hotly debated topics in obstetrics- should we be treating preeclampsia without severe features with antihypertensive medications during expectant management? Now, if you've been following the literature- and our show, you know that the landmark CHAP trial changed the game for chronic hypertension in pregnancy. It showed us that targeting a blood pressure below 140 over 90 reduces serious maternal complications, without harming the baby. That was a big deal. But here's the thing, CHAP studied chronic hypertension. Then there was the CHIP trial- that also found that tight control of gestational hypertension and nonproteinuric chronic hypertension was also beneficial. These did not address preeclampsia without severe features, and yet, the ripple effects of that trial have sparked a global conversation about whether we should be extending those same treatment principles to women with preeclampsia who don't yet have severe features. And this is where it gets really interesting, because the guidelines don't agree. In the United States, ACOG and the Society for Maternal-Fetal Medicine still say: hold off on antihypertensives unless blood pressures hit the severe range at 160/110. But step outside the US, and you'll find the World Health Organization, the International Society for the Study of Hypertension in Pregnancy, FIGO, NICE, and Hypertension Canada all recommending treatment at 140 over 90, regardless of whether the diagnosis is chronic hypertension, gestational hypertension, or preeclampsia. So who's right? And more importantly what does this mean for the patient sitting in front of you right now, at 34 weeks, with a blood pressure of 150 over 95, some proteinuria, but no severe features? Today, we're going to break this down. We'll review the controversy, walk through the divergent guidelines, and most importantly talk about the real, practical implications that favor treating these patients during expectant management. Because when you're watching someone with preeclampsia, waiting for the right time to deliver, there's a strong argument that controlling their blood pressure isn't just reasonable…may be protective. So grab your coffee, settle in, and let's get into it.

1. Society for Maternal-Fetal Medicine Statement: Antihypertensive Therapy For mild chronic Hypertension in Pregnancy-The Chronic Hypertension And Pregnancy Trial. American Journal of Obstetrics and Gynecology. 2022. Society for Maternal-Fetal Medicine; Publications Committee.

2. Preeclampsia. The New England Journal of Medicine. 2022. Magee LA, Nicolaides KH, von Dadelszen P.


3. Antihypertensive Drug Therapy for Mild to Moderate Hypertension During Pregnancy.The Cochrane Database of Systematic Reviews. 2018. Abalos E, Duley L, Steyn DW, C.

4. Prevention and Treatment of Maternal Stroke in Pregnancy and Postpartum: A Scientific Statement From the American Heart Association. Stroke. 2026. Miller EC, Bello NA, Chen PR, et al.

5.Hypertension in Pregnancy: Diagnosis, Blood Pressure Goals, and Pharmacotherapy: A Scientific Statement From the American Heart Association. Hypertension. 2022. Garovic VD, Dechend R, Easterling T, et al.


...more
View all episodesView all episodes
Download on the App Store

Dr. Chapa’s OBGYN Clinical PearlsBy Dr. Chapa’s Clinical Pearls

  • 4.1
  • 4.1
  • 4.1
  • 4.1
  • 4.1

4.1

447 ratings


More shows like Dr. Chapa’s OBGYN Clinical Pearls

View all
The Green Room: A Podcast from Obstetrics & Gynecology by Obstetrics & Gynecology (Green Journal)

The Green Room: A Podcast from Obstetrics & Gynecology

65 Listeners

White Coat Investor Podcast by Dr. Jim Dahle of the White Coat Investor

White Coat Investor Podcast

2,450 Listeners

The Curbsiders Internal Medicine Podcast by The Curbsiders Internal Medicine Podcast

The Curbsiders Internal Medicine Podcast

3,378 Listeners

Evidence Based Birth® by Rebecca Dekker, PhD, RN

Evidence Based Birth®

1,032 Listeners

Health By Heather Hirsch by Heather Hirsch

Health By Heather Hirsch

229 Listeners

CREOGs Over Coffee by CREOGs Over Coffee

CREOGs Over Coffee

558 Listeners

As a Woman by Natalie Crawford, MD

As a Woman

1,110 Listeners

You Are Not Broken by Kelly Casperson, MD

You Are Not Broken

1,163 Listeners

Fertility Docs Uncensored by Various

Fertility Docs Uncensored

285 Listeners

The Critical Care Obstetrics Podcast by Clinical Concepts in Obstetrics

The Critical Care Obstetrics Podcast

231 Listeners

All the Hacks: Money, Points & Life by Chris Hutchins

All the Hacks: Money, Points & Life

1,617 Listeners

Dr. Streicher’s Inside Information: Menopause, Midlife, and More by Lauren Streicher, MD

Dr. Streicher’s Inside Information: Menopause, Midlife, and More

355 Listeners

OvaryActive by Dr Rebecca Dunsmoor-Su, Dr Amy Voedisch

OvaryActive

88 Listeners

Dr. Chapa's OBGYN No Spin Podcast by Hector Chapa

Dr. Chapa's OBGYN No Spin Podcast

22 Listeners

unPAUSED with Dr. Mary Claire Haver by Audacy | Mary Claire Haver, MD

unPAUSED with Dr. Mary Claire Haver

1,233 Listeners