It has been a struggle to find drugs that slow the progression of osteoarthritis, rather than just manage the symptoms. 

But a common drug used to treat type 2 diabetes, metformin, is showing promise, not just in pain reduction but in improving knee cartilage. 

Guest/s

• Professor Flavia Cicuttini, Head of Rheumatology at Alfred Hospital and Musculoskeletal Unit at Monash University

References

• Metformin for Knee Osteoarthritis in Patients With Overweight or ObesityA Randomized Clinical Trial
• Metformin as a potential disease-modifying drug in osteoarthritis: a systematic review of pre-clinical and human studies