How to think about when and how to do RCTs? What are the limitations to observational studies?  Smoking. Parachutes. Dostarlimab. Guarantee Time Bias.  Confounding. Multiple Hypothesis testing and more

5.03 - VPs Grand Rounds Lecture - Evidence Based Medicine - Will it Survive?

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Patient advocates, Pharma funding, and is MRD a suitable endpoint

Patient advocates funded by Pharma

FDA makes MRD the basis for AA

Another flawed quality metric. Reviewing the NEJM paper "Beta-Blockers After Myocardial Infarction and Preserved Ejection Fraction".

Beta Blockers After Heart Attacks Don't Work

Blood based and Stool DNA colon cancer screening - Two NEJM papers

Another flawed study Keynote 564. Pembro in adjuvant RCC

5.03 - VPs Grand Rounds Lecture - Evidence Based Medicine - Will it Survive?

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