What if the earliest chapters of lifelong health are written in the gut — before a child even reaches preschool? Modern babies are often born without key microbes that train the immune system, leaving them more vulnerable to chronic conditions like allergies, asthma, and eczema.

This episode of The Russo Edge, Dr. Stephanie Culler, Co-founder and CEO of Persephone Biosciences, explains what makes the infant gut unique, why nine out of ten U.S. babies are born with microbiome deficiencies, and how her team is developing a synbiotic designed to replenish what’s lost.

From cancer research to dirty diapers, this is an entrepreneur's story of resilience, humor, and groundbreaking science — and why the smallest organisms in our gut may hold the biggest key to lifelong wellness.