In today’s show we continue our monthly Therapeutics Today (TT) newsletter discussion with Mary Teeling and MaryJo McAvin, Medical Advisors with The National Medicines Information Centre (NMIC) and co-authors of the TT newsletter.

Today we discuss papers on benzodiazepine and z-drug prescribing in Ireland, the impact of the HPV vaccine on prevalence of type-specific HPV, polypharmacy, and the effect of long term PPI use on pneumonia incidence.

You can receive the newsletter online at nmic.ie, or by post, by sending your details to [email protected]. You’ll get the most out of these discussions if you have the 2 page newsletter to hand. And as a reminder, I include lots of useful resources in the show notes, including hotlinks to the July NMIC newsletter discusses today, links to the original journal abstracts, and time stamps so you can jump to the section that interests you.

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NMIC Therapeutics Today July 2018 Newsletter:

http://www.stjames.ie/GPsHealthcareProfessionals/Newsletters/TherapeuticsToday/TherapeuticsToday2018/Therapeutics%20Today%20July%202018.pdf

NMIC Management Bulletins:

http://www.stjames.ie/GPsHealthcareProfessionals/Newsletters/NMICBulletins/

Chapters:

00:00:00 Intro "TT Jun 2018 Newsletter Link"

00:01:39 BZD and Z Drugs in Ireland (BJCP)

00:04:03 Medicines Management Programme

00:05:21 HPV Vaccination UK (JID)

00:10:46 Polypharmacy Guidance 2018 (Scotland)

00:15:13 PPI Use and Pneumonia Risk (J Am Geriatr Soc)

Links to Abstracts:

1) BJCP Feb 2018: Cadogan et al “Benzodiazepine and Z‐drug prescribing in Ireland: analysis of national prescribing trends from 2005 to 2015”

https://www.ncbi.nlm.nih.gov/pubmed/29488252

2) JID Jun 2018: Mesher et al “The Impact of the National HPV Vaccination Program in England Using the Bivalent HPV Vaccine: Surveillance of Type-Specific HPV in Young Females, 2010–2016”

https://www.ncbi.nlm.nih.gov/pubmed/?term=The+Impact+of+the+National+HPV+Vaccination+Program+in+England+Using+the+Bivalent+HPV+Vaccine%3A+Surveillance+of+Type-Specific+HPV+in+Young+Females%2C+2010%E2%80%932016

3) Polypharmacy Guidance – Realistic Prescribing 3rd Ed 2018

https://www.therapeutics.scot.nhs.uk/wp-content/uploads/2018/04/Polypharmacy-Guidance-2018.pdf

4) J Am Geriatr Soc July 2018: Zirk-Sadowski et al “Proton-Pump Inhibitors and Long-Term Risk of Community-Acquired Pneumonia in Older Adults”

https://www.ncbi.nlm.nih.gov/pubmed/29676433

Other Links:

MMP (Medicines Management Programme) Tips and Tools:

https://www.hse.ie/yourmedicines

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