This article explores how Artificial Intelligence (AI) transforms four key industries—healthcare, finance, manufacturing, and transportation—by enabling automation, data-driven decision-making, and increased efficiency. In healthcare, AI enhances diagnostics, drug discovery, and personalized medicine. In finance, it improves fraud detection, risk assessment, and algorithmic trading—manufacturing benefits from AI-driven predictive maintenance, production optimization, and quality control. In transportation, AI optimizes traffic management, enables autonomous vehicles, and enhances logistics planning. As AI continues to evolve, its integration into these industries drives innovation, improves productivity, and shapes the future of global economies.