Biopedia

10- The Lamellipodium

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As discussed in previous episodes, the actin cytoskeleton is vital to allow cells to move. But what about the specifics? In this episode, we’re going to be dissecting the lamellipodium- a meshwork actin structure that some cells use to move.


Sources for this episode:

  • Alberts, Johnson, Lewis, Raff, Roberts, and Walter (2008), Molecular Biology of the Cell, Fifth Edition. Abingdon: Garland Science, Taylor and Francis Group LLC.
  • Berro, Michelot, Blanchoin, Kovar and Martiel (2007), Attachment Conditions Control Actin Filament Buckling and the Production of Forces. Biophysical Journal 92(7): 2546- 2558.
  • Kiuchi, Ohashi, Kurita and Mizuno (2007), Cofilin promotes stimulus-induced lamellipodium formation by generating an abundant supply of actin monomers. The Journal of Cell Biology 177(3): 465- 476
  • ‘Mechanobiology Institute, Singapore’, YouTube (2013), Arp2/3 complex mediated actin nucleation (online) [Accessed 23/11/2020].
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