Artists Molly Schulman, Brice Bischoff, and I discuss the hypothesis that by 2045 exponential progress in bioengineering, nanotechnology, and robotics will lead to an Artificial Super Intelligence with the ability to self-replicate and evolve. Some versions of this future imagine robots the size of atoms boosting immune systems and cleaning the environment, while others predict a scenario in which the same robots attack the biosphere and destroy all life in a matter of days. Will humans become extinct, or immortal by merging with machines?